| An overview of inhibitors of Na+/H+ exchanger B Masereel, L Pochet, D Laeckmann European journal of medicinal chemistry 38 (6), 547-554, 2003 | 588 | 2003 |
| Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins A Maresca, C Temperini, L Pochet, B Masereel, A Scozzafava, ... Journal of medicinal chemistry 53 (1), 335-344, 2010 | 440 | 2010 |
| Tryptophan 2, 3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl) ethenyl) indoles as potential anticancer immunomodulators E Dolušić, P Larrieu, L Moineaux, V Stroobant, L Pilotte, D Colau, ... Journal of medicinal chemistry 54 (15), 5320-5334, 2011 | 209 | 2011 |
| 3-Bromophenyl 6-acetoxymethyl-2-oxo-2H-1-benzopyran-3-carboxylate inhibits cancer cell invasion in vitro and tumour growth in vivo I Kempen, D Papapostolou, N Thierry, L Pochet, S Counerotte, ... British Journal of Cancer 88 (7), 1111-1118, 2003 | 140 | 2003 |
| Coumarin and isocoumarin as serine protease inhibitors L Pochet, R Frédérick, B Masereel Current pharmaceutical design 10 (30), 3781-3796, 2004 | 124 | 2004 |
| Esters and amides of 6-(chloromethyl)-2-oxo-2 H-1-benzopyran-3-carboxylic acid as inhibitors of α-chymotrypsin: significance of the “aromatic” nature of the novel ester-type … L Pochet, C Doucet, M Schynts, N Thierry, N Boggetto, B Pirotte, KY Jiang, ... Journal of medicinal chemistry 39 (13), 2579-2585, 1996 | 122 | 1996 |
| Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors S Robert, C Bertolla, B Masereel, JM Dogné, L Pochet Journal of medicinal chemistry 51 (11), 3077-3080, 2008 | 108 | 2008 |
| Novel trisubstituted harmine derivatives with original in vitro anticancer activity R Frédérick, C Bruyère, C Vancraeynest, J Reniers, C Meinguet, L Pochet, ... Journal of medicinal chemistry 55 (14), 6489-6501, 2012 | 96 | 2012 |
| 3, 6-Disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa R Frédérick, S Robert, C Charlier, J de Ruyck, J Wouters, B Pirotte, ... Journal of medicinal chemistry 48 (24), 7592-7603, 2005 | 84 | 2005 |
| 6-Substituted 2-Oxo-2H-1-benzopyran-3-carboxylic Acid as a Core Structure for Specific Inhibitors of Human Leukocyte Elastase C Doucet, L Pochet, N Thierry, B Pirotte, J Delarge, M Reboud-Ravaux Journal of medicinal chemistry 42 (20), 4161-4171, 1999 | 83 | 1999 |
| Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs? S Robert, J Ghiotto, B Pirotte, JL David, B Masereel, L Pochet, JM Dogné Pharmacological research 59 (3), 160-166, 2009 | 68 | 2009 |
| 6-Substituted 2-oxo-2H-1-benzopyran-3-carboxylic acid derivatives in a new approach of the treatment of cancer cell invasion and metastasis I Kempen, M Hemmer, S Counerotte, L Pochet, P De Tullio, JM Foidart, ... European journal of medicinal chemistry 43 (12), 2735-2750, 2008 | 64 | 2008 |
| Coumarinic derivatives as mechanism-based inhibitors of α-chymotrypsin and human leukocyte elastase L Pochet, C Doucet, G Dive, J Wouters, B Masereel, M Reboud-Ravaux, ... Bioorganic & medicinal chemistry 8 (6), 1489-1501, 2000 | 58 | 2000 |
| Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors C Bouckaert, S Serra, G Rondelet, E Dolušić, J Wouters, JM Dogné, ... European Journal of Medicinal Chemistry 110, 181-194, 2016 | 50 | 2016 |
| Modulators of the coagulation cascade: focus and recent advances in inhibitors of tissue factor, factor VIIa and their complex R Frédérick, L Pochet, C Charlier, B Masereel Current medicinal chemistry 12 (4), 397-417, 2005 | 47 | 2005 |
| Enhancing action of positive allosteric modulators through the design of dimeric compounds T Drapier, P Geubelle, C Bouckaert, L Nielsen, S Laulumaa, E Goffin, ... Journal of Medicinal Chemistry 61 (12), 5279-5291, 2018 | 46 | 2018 |
| Factor XII/XIIa inhibitors: Their discovery, development, and potential indications C Davoine, C Bouckaert, M Fillet, L Pochet European Journal of Medicinal Chemistry 208, 112753, 2020 | 44 | 2020 |
| Thiosemicarbazide, a fragment with promising indolamine-2, 3-dioxygenase (IDO) inhibition properties S Serra, L Moineaux, C Vancraeynest, B Masereel, J Wouters, L Pochet, ... European Journal of Medicinal Chemistry 82, 96-105, 2014 | 44 | 2014 |
| Mechanism-Based Thrombin Inhibitors: Design, Synthesis, and Molecular Docking of a New Selective 2-Oxo-2H-1-benzopyran Derivative R Frédérick, S Robert, C Charlier, J Wouters, B Masereel, L Pochet Journal of medicinal chemistry 50 (15), 3645-3650, 2007 | 42 | 2007 |
| Investigation of mechanism-based thrombin inhibitors: Implications of a highly conserved water molecule for the binding of coumarins within the S pocket R Frédérick, C Charlier, S Robert, J Wouters, B Masereel, L Pochet Bioorganic & medicinal chemistry letters 16 (7), 2017-2021, 2006 | 38 | 2006 |
