Holger Grohganz
Holger Grohganz
Associate Professor, University of Copenhagen
Bekræftet mail på sund.ku.dk - Startside
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Emerging trends in the stabilization of amorphous drugs
R Laitinen, K Löbmann, CJ Strachan, H Grohganz, T Rades
International journal of pharmaceutics 453 (1), 65-79, 2013
3542013
Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen
K Löbmann, R Laitinen, H Grohganz, KC Gordon, C Strachan, T Rades
Molecular pharmaceutics 8 (5), 1919-1928, 2011
2852011
Recent advances in co-amorphous drug formulations
SJ Dengale, H Grohganz, T Rades, K Löbmann
Advanced drug delivery reviews 100, 116-125, 2016
2592016
Amino acids as co-amorphous stabilizers for poorly water soluble drugs–Part 1: Preparation, stability and dissolution enhancement
K Löbmann, H Grohganz, R Laitinen, C Strachan, T Rades
European journal of pharmaceutics and biopharmaceutics 85 (3), 873-881, 2013
2272013
Co-amorphous simvastatin and glipizide combinations show improved physical stability without evidence of intermolecular interactions
K Löbmann, C Strachan, H Grohganz, T Rades, O Korhonen, R Laitinen
European Journal of Pharmaceutics and Biopharmaceutics 81 (1), 159-169, 2012
1772012
Amino acids as co-amorphous stabilizers for poorly water-soluble drugs–Part 2: Molecular interactions
K Löbmann, R Laitinen, C Strachan, T Rades, H Grohganz
European Journal of Pharmaceutics and Biopharmaceutics 85 (3), 882-888, 2013
1332013
Design space approach in the optimization of the spray-drying process
P Lebrun, F Krier, J Mantanus, H Grohganz, M Yang, E Rozet, ...
European Journal of Pharmaceutics and Biopharmaceutics 80 (1), 226-234, 2012
1242012
Recent trends in stabilising peptides and proteins in pharmaceutical formulation–considerations in the choice of excipients
L Jorgensen, S Hostrup, EH Moeller, H Grohganz
Expert opinion on drug delivery 6 (11), 1219-1230, 2009
1182009
Refining stability and dissolution rate of amorphous drug formulations
H Grohganz, PA Priemel, K Löbmann, LH Nielsen, R Laitinen, A Mullertz, ...
Expert opinion on drug delivery 11 (6), 977-989, 2014
1122014
A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin
K Löbmann, R Laitinen, H Grohganz, C Strachan, T Rades, KC Gordon
International journal of pharmaceutics 453 (1), 80-87, 2013
1012013
Improving co-amorphous drug formulations by the addition of the highly water soluble amino acid, proline
KT Jensen, K Löbmann, T Rades, H Grohganz
Pharmaceutics 6 (3), 416-435, 2014
892014
Preparation and characterization of spray‐dried co‐amorphous drug–amino acid salts
KT Jensen, LI Blaabjerg, E Lenz, A Bohr, H Grohganz, P Kleinebudde, ...
Journal of Pharmacy and Pharmacology 68 (5), 615-624, 2016
882016
Amino acids as co-amorphous excipients for simvastatin and glibenclamide: physical properties and stability
R Laitinen, K Lobmann, H Grohganz, C Strachan, T Rades
Molecular pharmaceutics 11 (7), 2381-2389, 2014
842014
Formation mechanism of coamorphous drug–amino acid mixtures
KT Jensen, FH Larsen, C Cornett, K Löbmann, H Grohganz, T Rades
Molecular pharmaceutics 12 (7), 2484-2492, 2015
692015
Supersaturating drug delivery systems: the potential of co-amorphous drug formulations
R Laitinen, K Löbmann, H Grohganz, P Priemel, CJ Strachan, T Rades
International journal of pharmaceutics 532 (1), 1-12, 2017
642017
Glass-transition temperature of the β-relaxation as the major predictive parameter for recrystallization of neat amorphous drugs
EO Kissi, H Grohganz, K Löbmann, MT Ruggiero, JA Zeitler, T Rades
The Journal of Physical Chemistry B 122 (10), 2803-2808, 2018
632018
Solid-state properties and dissolution behaviour of tablets containing co-amorphous indomethacin–arginine
E Lenz, KT Jensen, LI Blaabjerg, K Knop, H Grohganz, K Löbmann, ...
European Journal of Pharmaceutics and Biopharmaceutics 96, 44-52, 2015
622015
Amorphous drugs and dosage forms
H Grohganz, K Löbmann, P Priemel, KT Jensen, K Graeser, C Strachan, ...
Journal of Drug Delivery Science and Technology 23 (4), 403-408, 2013
552013
Development of a screening method for co-amorphous formulations of drugs and amino acids
G Kasten, H Grohganz, T Rades, K Löbmann
European Journal of Pharmaceutical Sciences 95, 28-35, 2016
542016
Theoretical considerations in developing amorphous solid dispersions
R Laitinen, PA Priemel, S Surwase, K Graeser, CJ Strachan, H Grohganz, ...
Amorphous solid dispersions, 35-90, 2014
522014
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