Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells Y Wang, KI Liu, NAB Sutrisnoh, H Srinivasan, J Zhang, J Li, F Zhang, ... Genome biology 19, 1-16, 2018 | 97 | 2018 |
Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer M Pek, S Yatim, Y Chen, J Li, M Gong, X Jiang, F Zhang, J Zheng, X Wu, ... Oncogene 36 (35), 4975-4986, 2017 | 83 | 2017 |
Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator H Liu, PA Lorenzini, F Zhang, S Xu, MSM Wong, J Zheng, X Roca Nucleic acids research 46 (12), 6069-6086, 2018 | 69 | 2018 |
Comparison of radiomics tools for image analyses and clinical prediction in nasopharyngeal carcinoma ZG Liang, HQ Tan, F Zhang, LK Rui Tan, L Lin, J Lenkowicz, H Wang, ... The British Journal of Radiology 92 (1102), 20190271, 2019 | 53 | 2019 |
In Silico Prediction of Synthetic Lethality by Meta-Analysis of Genetic Interactions, Functions, and Pathways in Yeast and Human Cancer M Wu, X Li, F Zhang, X Li, CK Kwoh, J Zheng Cancer informatics 13 (Suppl 3), 71-80, 2014 | 42 | 2014 |
Syn‐lethality: an integrative knowledge base of synthetic lethality towards discovery of selective anticancer therapies X Li, SK Mishra, M Wu, F Zhang, J Zheng BioMed research international 2014 (1), 196034, 2014 | 40 | 2014 |
Predicting essential genes and synthetic lethality via influence propagation in signaling pathways of cancer cell fates F Zhang, M Wu, X Li, X Li, CK Kwoh, J Zheng Journal of bioinformatics and computational biology 13, 1541002, 2015 | 31 | 2015 |
SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates R Shanmugam, F Zhang, H Srinivasan, JL Charles Richard, KI Liu, ... Nucleic acids research 46 (14), 7379-7395, 2018 | 28 | 2018 |
The use of targeted exome sequencing in genetic diagnosis of young patients with severe hypercholesterolemia L Jiang, WF Wu, LY Sun, PP Chen, W Wang, A Benito-Vicente, F Zhang, ... Scientific reports 6 (1), 36823, 2016 | 23 | 2016 |
Human PRPF40B regulates hundreds of alternative splicing targets and represses a hypoxia expression signature PA Lorenzini, RSE Chew, CW Tan, JY Yong, F Zhang, J Zheng, X Roca Rna 25 (8), 905-920, 2019 | 19 | 2019 |
Integrated analysis of transcriptomes of cancer cell lines and patient samples reveals STK11/LKB1–driven regulation of cAMP phosphodiesterase-4D N He, N Kim, M Song, C Park, S Kim, EY Park, HY Yim, K Kim, JH Park, ... Molecular cancer therapeutics 13 (10), 2463-2473, 2014 | 19 | 2014 |
Knowledge-guided fuzzy logic modeling to infer cellular signaling networks from proteomic data H Liu, F Zhang, SK Mishra, S Zhou, J Zheng Scientific reports 6 (1), 35652, 2016 | 18 | 2016 |
Computational cell fate modelling for discovery of rewiring in apoptotic network for enhanced cancer drug sensitivity SK Mishra, SS Bhowmick, HE Chua, F Zhang, J Zheng BMC Systems Biology 9 (Suppl 1), S4, 2015 | 11 | 2015 |
Polypharmacy with high Drug Burden Index (DBI) alters the gut microbiome overriding aging effects and is reversible with deprescribing G Gemikonakli, J Mach, F Zhang, M Bullock, T Tran, E El-Omar, SN Hilmer The Journals of Gerontology: Series A 78 (2), 213-222, 2023 | 10 | 2023 |
Fecal DNA virome is associated with the development of colorectal neoplasia in a murine model of colorectal cancer Y Li, F Zhang, H Zheng, S Kalasabail, C Hicks, KY Fung, A Preaudet, ... Pathogens 11 (4), 457, 2022 | 9 | 2022 |
Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7 J Chen, Y Zhao, F Zhang, J Li, JA Boland, NC Cheng, K Liu, JC Tiffen, ... Cellular and Molecular Life Sciences 79 (8), 443, 2022 | 8 | 2022 |
Meta-analysis of genomic and proteomic features to predict synthetic lethality of yeast and human cancer M Wu, X Li, F Zhang, X Li, CK Kwoh, J Zheng Proceedings of the International Conference on Bioinformatics, Computational …, 2013 | 8 | 2013 |
Dysbiosis in head and neck cancer: determining optimal sampling site for oral microbiome collection D Pandey, M Szczesniak, J Maclean, HCH Yim, F Zhang, P Graham, ... Pathogens 11 (12), 1550, 2022 | 6 | 2022 |
Sig2GRN: a software tool linking signaling pathway with gene regulatory network for dynamic simulation F Zhang, R Liu, J Zheng BMC Systems Biology 10, 541-548, 2016 | 5 | 2016 |
Data-driven prediction of cancer cell fates with a nonlinear model of signaling pathways F Zhang, CK Kwoh, M Wu, J Zheng Proceedings of the 5th ACM Conference on Bioinformatics, Computational …, 2014 | 5 | 2014 |