| Structure of a hallucinogen-activated Gq-coupled 5-HT2A serotonin receptor K Kim, T Che, O Panova, JF DiBerto, J Lyu, BE Krumm, D Wacker, ... Cell 182 (6), 1574-1588. e19, 2020 | 378 | 2020 |
| Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity AL Kaplan, DN Confair, K Kim, X Barros-Álvarez, RM Rodriguiz, Y Yang, ... Nature 610 (7932), 582-591, 2022 | 162 | 2022 |
| Structure, function and pharmacology of human itch GPCRs C Cao, HJ Kang, I Singh, H Chen, C Zhang, W Ye, BW Hayes, J Liu, ... Nature 600 (7887), 170-175, 2021 | 141 | 2021 |
| Nanobody-enabled monitoring of kappa opioid receptor states T Che, J English, BE Krumm, K Kim, E Pardon, RHJ Olsen, S Wang, ... Nature communications 11 (1), 1145, 2020 | 114 | 2020 |
| Monomerization and ER relocalization of GRASP is a requisite for unconventional secretion of CFTR J Kim, SH Noh, H Piao, DH Kim, K Kim, JS Cha, WY Chung, HS Cho, ... Traffic 17 (7), 733-753, 2016 | 81 | 2016 |
| Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD C Cao, X Barros-Álvarez, S Zhang, K Kim, MA Dämgen, O Panova, ... Neuron 110 (19), 3154-3167. e7, 2022 | 80 | 2022 |
| Crystal structure and functional characterization of a light-driven chloride pump having an NTQ motif K Kim, SK Kwon, SH Jun, JS Cha, H Kim, W Lee, JF Kim, HS Cho Nature communications 7 (1), 12677, 2016 | 67 | 2016 |
| Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation SA Jeong, K Kim, JH Lee, JS Cha, P Khadka, HS Cho, IK Chung Journal of cell science 128 (12), 2287-2301, 2015 | 53 | 2015 |
| Molecular mechanism of biased signaling at the kappa opioid receptor A El Daibani, JM Paggi, K Kim, YD Laloudakis, P Popov, SM Bernhard, ... Nature communications 14 (1), 1338, 2023 | 47 | 2023 |
| GC1118, an anti-EGFR antibody with a distinct binding epitope and superior inhibitory activity against high-affinity EGFR ligands Y Lim, J Yoo, MS Kim, M Hur, EH Lee, HS Hur, JC Lee, SN Lee, TW Park, ... Molecular cancer therapeutics 15 (2), 251-263, 2016 | 38 | 2016 |
| A missense allele of KARRIKIN-INSENSITIVE2 impairs ligand-binding and downstream signaling in Arabidopsis thaliana I Lee, K Kim, S Lee, S Lee, E Hwang, K Shin, D Kim, J Choi, H Choi, ... Journal of experimental botany 69 (15), 3609-3623, 2018 | 27 | 2018 |
| The crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inhibitor YS Cho, YJ Kang, K Kim, Y Cha, HS Cho Biochemical and biophysical research communications 447 (1), 7-11, 2014 | 27 | 2014 |
| Crystal structure of GSK3β in complex with the flavonoid, morin K Kim, JS Cha, JS Kim, J Ahn, NC Ha, HS Cho Biochemical and biophysical research communications 504 (2), 519-524, 2018 | 22 | 2018 |
| Structural Basis for the Inhibition of Human Lysozyme by PliC from Brucella abortus SH Um, JS Kim, K Kim, N Kim, HS Cho, NC Ha Biochemistry 52 (51), 9385-9393, 2013 | 22 | 2013 |
| AlphaFold2 structures guide prospective ligand discovery J Lyu, N Kapolka, R Gumpper, A Alon, L Wang, MK Jain, X Barros-Álvarez, ... Science, eadn6354, 2024 | 21 | 2024 |
| Inactive and active state structures template selective tools for the human 5-HT5A receptor S Zhang, H Chen, C Zhang, Y Yang, P Popov, J Liu, BE Krumm, C Cao, ... Nature structural & molecular biology 29 (7), 677-687, 2022 | 20 | 2022 |
| In Vitro and In Vivo Investigation of the Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates G Yang, W Zhu, K Kim, SY Byun, G Choi, K Wang, JS Cha, HS Cho, ... Antimicrobial agents and chemotherapy 59 (12), 7530-7539, 2015 | 20 | 2015 |
| Crystal structure of human dual-specificity tyrosine-regulated kinase 3 reveals new structural features and insights into its auto-phosphorylation K Kim, JS Cha, YS Cho, H Kim, N Chang, HJ Kim, HS Cho Journal of Molecular Biology 430 (10), 1521-1530, 2018 | 13 | 2018 |
| Solution structure of the transmembrane 2 domain of the human melanocortin-4 receptor in sodium dodecyl sulfate (SDS) micelles and the functional implication of the D90N mutant JH Yun, M Kim, K Kim, D Lee, Y Jung, D Oh, YJ Ko, AE Cho, HS Cho, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (6), 1294-1302, 2015 | 11 | 2015 |
| AlphaFold2 structures template ligand discovery J Lyu, N Kapolka, R Gumpper, A Alon, L Wang, MK Jain, X Barros-Álvarez, ... BioRxiv, 2023 | 8 | 2023 |
Hyun-Soo ChoProfessor, Dept. of Systems Biology, Yonsei UniversityVerified email at yonsei.ac.kr
