Kuglae Kim
Kuglae Kim
Assistant Professor of Pharmacy, Yonsei University
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Structure of a hallucinogen-activated Gq-coupled 5-HT2A serotonin receptor
K Kim, T Che, O Panova, JF DiBerto, J Lyu, BE Krumm, D Wacker, ...
Cell 182 (6), 1574-1588. e19, 2020
Nanobody-enabled monitoring of kappa opioid receptor states
T Che, J English, BE Krumm, K Kim, E Pardon, RHJ Olsen, S Wang, ...
Nature communications 11 (1), 1145, 2020
Structure, function and pharmacology of human itch GPCRs
C Cao, HJ Kang, I Singh, H Chen, C Zhang, W Ye, BW Hayes, J Liu, ...
Nature 600 (7887), 170-175, 2021
Monomerization and ER relocalization of GRASP is a requisite for unconventional secretion of CFTR
J Kim, SH Noh, H Piao, DH Kim, K Kim, JS Cha, WY Chung, HS Cho, ...
Traffic 17 (7), 733-753, 2016
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity
AL Kaplan, DN Confair, K Kim, X Barros-┴lvarez, RM Rodriguiz, Y Yang, ...
Nature 610 (7932), 582-591, 2022
Crystal structure and functional characterization of a light-driven chloride pump having an NTQ motif
K Kim, SK Kwon, SH Jun, JS Cha, H Kim, W Lee, JF Kim, HS Cho
Nature communications 7 (1), 12677, 2016
Akt-mediated phosphorylation increases the binding affinity of hTERT for importin α to promote nuclear translocation
SA Jeong, K Kim, JH Lee, JS Cha, P Khadka, HS Cho, IK Chung
Journal of cell science 128 (12), 2287-2301, 2015
Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD
C Cao, X Barros-┴lvarez, S Zhang, K Kim, MA Dńmgen, O Panova, ...
Neuron 110 (19), 3154-3167. e7, 2022
GC1118, an anti-EGFR antibody with a distinct binding epitope and superior inhibitory activity against high-affinity EGFR ligands
Y Lim, J Yoo, MS Kim, M Hur, EH Lee, HS Hur, JC Lee, SN Lee, TW Park, ...
Molecular cancer therapeutics 15 (2), 251-263, 2016
The crystal structure of MPK38 in complex with OTSSP167, an orally administrative MELK selective inhibitor
YS Cho, YJ Kang, K Kim, Y Cha, HS Cho
Biochemical and biophysical research communications 447 (1), 7-11, 2014
A missense allele of KARRIKIN-INSENSITIVE2 impairs ligand-binding and downstream signaling in Arabidopsis thaliana
I Lee, K Kim, S Lee, S Lee, E Hwang, K Shin, D Kim, J Choi, H Choi, ...
Journal of experimental botany 69 (15), 3609-3623, 2018
Structural Basis for the Inhibition of Human Lysozyme by PliC from Brucella abortus
SH Um, JS Kim, K Kim, N Kim, HS Cho, NC Ha
Biochemistry 52 (51), 9385-9393, 2013
In Vitro and In Vivo Investigation of the Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates
G Yang, W Zhu, K Kim, SY Byun, G Choi, K Wang, JS Cha, HS Cho, ...
Antimicrobial agents and chemotherapy 59 (12), 7530-7539, 2015
Crystal structure of GSK3β in complex with the flavonoid, morin
K Kim, JS Cha, JS Kim, J Ahn, NC Ha, HS Cho
Biochemical and biophysical research communications 504 (2), 519-524, 2018
Crystal structure of human dual-specificity tyrosine-regulated kinase 3 reveals new structural features and insights into its auto-phosphorylation
K Kim, JS Cha, YS Cho, H Kim, N Chang, HJ Kim, HS Cho
Journal of Molecular Biology 430 (10), 1521-1530, 2018
Solution structure of the transmembrane 2 domain of the human melanocortin-4 receptor in sodium dodecyl sulfate (SDS) micelles and the functional implication of the D90N mutant
JH Yun, M Kim, K Kim, D Lee, Y Jung, D Oh, YJ Ko, AE Cho, HS Cho, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (6), 1294-1302, 2015
Inactive and active state structures template selective tools for the human 5-HT5A receptor
S Zhang, H Chen, C Zhang, Y Yang, P Popov, J Liu, BE Krumm, C Cao, ...
Nature structural & molecular biology 29 (7), 677-687, 2022
Molecular mechanism of biased signaling at the kappa opioid receptor
A El Daibani, JM Paggi, K Kim, YD Laloudakis, P Popov, SM Bernhard, ...
Nature communications 14 (1), 1338, 2023
Nanobody-enabled monitoring of kappa opioid receptor states. Nat Commun 11: 1145
T Che, J English, BE Krumm, K Kim, E Pardon, RHJ Olsen, S Wang, ...
Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4
EK Kwon, CK Min, Y Kim, JW Lee, A Aigerim, S Schmidt, HJ Nam, SK Han, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (1), 1-11, 2017
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