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Thomas Jepps
Thomas Jepps
Associate Professor
Verificeret mail på sund.ku.dk - Startside
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Downregulation of Kv7. 4 channel activity in primary and secondary hypertension
TA Jepps, PS Chadha, AJ Davis, MI Harhun, GW Cockerill, SP Olesen, ...
Circulation 124 (5), 602-611, 2011
1722011
Expression and function of the K+ channel KCNQ genes in human arteries
FL Ng, AJ Davis, TA Jepps, MI Harhun, SY Yeung, A Wan, M Reddy, ...
British journal of pharmacology 162 (1), 42-53, 2011
1502011
Expression profile and protein translation of TMEM16A in murine smooth muscle
AJ Davis, AS Forrest, TA Jepps, ML Valencik, M Wiwchar, CA Singer, ...
American Journal of Physiology-Cell Physiology 299 (5), C948-C959, 2010
1402010
Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired β-adrenoceptor–mediated relaxation of renal arteries in hypertension
PS Chadha, F Zunke, HL Zhu, AJ Davis, TA Jepps, SP Olesen, WC Cole, ...
Hypertension 59 (4), 877-884, 2012
1252012
KV7 potassium channels: a new therapeutic target in smooth muscle disorders
JB Stott, TA Jepps, IA Greenwood
Drug discovery today 19 (4), 413-424, 2014
1172014
Contribution of Kv7. 4/Kv7. 5 heteromers to intrinsic and calcitonin gene-related peptide–induced cerebral reactivity
PS Chadha, TA Jepps, G Carr, JB Stott, HL Zhu, WC Cole, IA Greenwood
Arteriosclerosis, thrombosis, and vascular biology 34 (4), 887-893, 2014
1002014
Contribution of Kv7 Channels to Basal Coronary Flow and Active Response to Ischemia
S Khanamiri, E Soltysinska, TA Jepps, BH Bentzen, PS Chadha, ...
Hypertension 62 (6), 1090-1097, 2013
912013
Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles
TA Jepps, IA Greenwood, JD Moffatt, KM Sanders, S Ohya
American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (1 …, 2009
832009
Fundamental role for the KCNE4 ancillary subunit in Kv7. 4 regulation of arterial tone
TA Jepps, G Carr, PR Lundegaard, SP Olesen, IA Greenwood
The Journal of physiology 593 (24), 5325-5340, 2015
772015
Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats
JB Stott, V Barrese, TA Jepps, EV Leighton, IA Greenwood
Hypertension 65 (3), 676-682, 2015
692015
Pharmacological dissection of Kv7.1 channels in systemic and pulmonary arteries
PS Chadha, F Zunke, AJ Davis, TA Jepps, JTM Linders, M Schwake, ...
British journal of pharmacology 166 (4), 1377-1387, 2012
662012
One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders
TA Jepps, SP Olesen, IA Greenwood
British journal of pharmacology 168 (1), 19-27, 2013
602013
MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension
G Carr, V Barrese, JB Stott, OV Povstyan, TA Jepps, HB Figueiredo, ...
Cardiovascular research 112 (2), 581-589, 2016
562016
Vasorelaxant effects of novel Kv7.4 channel enhancers ML213 and NS15370
TA Jepps, BH Bentzen, JB Stott, OV Povstyan, K Sivaloganathan, ...
British journal of pharmacology 171 (19), 4413-4424, 2014
482014
Kcne4 deletion sex-dependently alters vascular reactivity
GW Abbott, TA Jepps
Journal of vascular research 53 (3-4), 138-148, 2016
392016
KCNQ5 activation is a unifying molecular mechanism shared by genetically and culturally diverse botanical hypotensive folk medicines
RW Manville, J Van Der Horst, KE Redford, BB Katz, TA Jepps, GW Abbott
Proceedings of the National Academy of Sciences 116 (42), 21236-21245, 2019
382019
TMEM16A is implicated in the regulation of coronary flow and is altered in hypertension
HR Askew Page, T Dalsgaard, SN Baldwin, TA Jepps, O Povstyan, ...
British Journal of Pharmacology 176 (11), 1635-1648, 2019
382019
Cyclic AMP-dependent regulation of Kv7 voltage-gated potassium channels
J Van der Horst, IA Greenwood, TA Jepps
Frontiers in physiology 11, 559456, 2020
342020
Molecular and functional characterization of Kv7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats
TA Jepps, SP Olesen, IA Greenwood, T Dalsgaard
British journal of pharmacology 173 (9), 1478-1490, 2016
292016
4‐aminopyridine: a pan Kv channel inhibitor that enhances Kv7. 4 currents and inhibits noradrenaline‐mediated contraction of rat mesenteric small arteries
MM Khammy, S Kim, BH Bentzen, S Lee, I Choi, C Aalkjær, TA Jepps
British Journal of Pharmacology, 2017
28*2017
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Artikler 1–20