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Lynn Spruce
Lynn Spruce
Other namesLynn A. Spruce
Technical Director, CHOP-PENN Proteomics Core, Children's Hospital of Philadelphia
Verified email at chop.edu
Title
Cited by
Cited by
Year
Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
G Girardi, J Berman, P Redecha, L Spruce, JM Thurman, D Kraus, ...
The Journal of clinical investigation 112 (11), 1644-1654, 2003
8072003
The proinflammatory mediators C3a and C5a are essential for liver regeneration
CW Strey, M Markiewski, D Mastellos, R Tudoran, LA Spruce, ...
The Journal of experimental medicine 198 (6), 913-923, 2003
5202003
Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry
JC Whitbeck, C Peng, H Lou, R Xu, SH Willis, M Ponce de Leon, T Peng, ...
Journal of virology 71 (8), 6083-6093, 1997
3841997
Anti-NMDA receptor encephalitis antibody binding is dependent on amino acid identity of a small region within the GluN1 amino terminal domain
AJ Gleichman, LA Spruce, J Dalmau, SH Seeholzer, DR Lynch
Journal of Neuroscience 32 (32), 11082-11094, 2012
3012012
Ice-age endurance: DNA evidence of a white spruce refugium in Alaska
LL Anderson, FS Hu, DM Nelson, RJ Petit, KN Paige
Proceedings of the National Academy of Sciences 103 (33), 12447-12450, 2006
2952006
Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1
R Reca, D Mastellos, M Majka, L Marquez, J Ratajczak, S Franchini, ...
Blood, The Journal of the American Society of Hematology 101 (10), 3784-3793, 2003
2662003
Protection of innate immunity by C5aR antagonist in septic mice
MS Huber‐Lang, NC Riedeman, JV Sarma, EM Younkin, SR McGuire, ...
Wiley Periodicals, Inc., 2002
2112002
Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria
EN Genda, JG Jackson, AL Sheldon, SF Locke, TM Greco, JC O'Donnell, ...
Journal of Neuroscience 31 (50), 18275-18288, 2011
2042011
The diabetes susceptibility gene Clec16a regulates mitophagy
SA Soleimanpour, A Gupta, M Bakay, AM Ferrari, DN Groff, J Fadista, ...
Cell 157 (7), 1577-1590, 2014
1982014
Sustained release of endothelial progenitor cell-derived extracellular vesicles from shear-thinning hydrogels improves angiogenesis and promotes function after myocardial …
CW Chen, LL Wang, S Zaman, J Gordon, MF Arisi, CM Venkataraman, ...
Cardiovascular research 114 (7), 1029-1040, 2018
1802018
Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy
J Schessl, Y Zou, MJ McGrath, BS Cowling, B Maiti, SS Chin, C Sewry, ...
The Journal of clinical investigation 118 (3), 904-912, 2008
1632008
Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor compstatin
A Sahu, AM Soulika, D Morikis, L Spruce, WT Moore, JD Lambris
The Journal of Immunology 165 (5), 2491-2499, 2000
1522000
Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts
AE Fiane, TE Mollnes, V Videm, T Hovig, K Høgåsen, OJ Mellbye, ...
Xenotransplantation 6 (1), 52-65, 1999
1351999
Design and NMR characterization of active analogues of compstatin containing non-natural amino acids
B Mallik, M Katragadda, LA Spruce, C Carafides, CG Tsokos, D Morikis, ...
Journal of medicinal chemistry 48 (1), 274-286, 2005
1222005
Integrated computational and experimental approach for lead optimization and design of compstatin variants with improved activity
JL Klepeis, CA Floudas, D Morikis, CG Tsokos, E Argyropoulos, L Spruce, ...
Journal of the American Chemical Society 125 (28), 8422-8423, 2003
1172003
Quantitative mass spectrometry-based proteomics reveals the dynamic range of primary mouse astrocyte protein secretion
TM Greco, SH Seeholzer, A Mak, L Spruce, H Ischiropoulos
Journal of proteome research 9 (5), 2764-2774, 2010
1102010
The HtrA protease from Streptococcus pneumoniae digests both denatured proteins and the competence-stimulating peptide
M Cassone, AL Gagne, LA Spruce, SH Seeholzer, ME Sebert
Journal of Biological Chemistry 287 (46), 38449-38459, 2012
1062012
CiC3-1a-mediated chemotaxis in the deuterostome invertebrate Ciona intestinalis (Urochordata)
MR Pinto, CM Chinnici, Y Kimura, D Melillo, R Marino, LA Spruce, ...
The Journal of Immunology 171 (10), 5521-5528, 2003
942003
Studies of structure-activity relations of complement inhibitor compstatin
AM Soulika, D Morikis, MR Sarrias, M Roy, LA Spruce, A Sahu, ...
The Journal of Immunology 171 (4), 1881-1890, 2003
602003
Identifying host factors associated with DNA replicated during virus infection
ED Reyes, K Kulej, NJ Pancholi, LN Akhtar, DC Avgousti, ET Kim, ...
Molecular & cellular proteomics 16 (12), 2079-2097, 2017
592017
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