Annette Burkhart (Larsen)
Annette Burkhart (Larsen)
Associate Professor, Aalborg University
Verified email at
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Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma.
KB Johnsen, A Burkhart, T Moos
Scientific reports, 2007
Targeting the transferrin receptor for brain drug delivery
KB Johnsen, A Burkhart, LB Thomsen, TL Andresen, T Moos
Progress in neurobiology 181, 101665, 2019
A triple culture model of the blood-brain barrier using porcine brain endothelial cells, astrocytes and pericytes
LB Thomsen, A Burkhart, T Moos
PloS one 10 (8), e0134765, 2015
Divalent metal transporter 1 (DMT1) in the brain: implications for a role in iron transport at the blood-brain barrier, and neuronal and glial pathology
T Skjørringe, A Burkhart, KB Johnsen, T Moos
Frontiers in Molecular Neuroscience 8, 19, 2015
Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo
KB Johnsen, M Bak, F Melander, MS Thomsen, A Burkhart, PJ Kempen, ...
Journal of Controlled Release 295, 237-249, 2019
Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles
KB Johnsen, M Bak, PJ Kempen, F Melander, A Burkhart, MS Thomsen, ...
Theranostics 8 (12), 3416, 2018
Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier
A Burkhart, T Skjørringe, KB Johnsen, P Siupka, LB Thomsen, MS Nielsen, ...
Molecular neurobiology 53 (10), 7237-7253, 2016
Synthesis and deposition of basement membrane proteins by primary brain capillary endothelial cells in a murine model of the blood–brain barrier
MS Thomsen, S Birkelund, A Burkhart, A Stensballe, T Moos
Journal of neurochemistry 140 (5), 741-754, 2017
Transfection of brain capillary endothelial cells in primary culture with defined blood–brain barrier properties
A Burkhart, LB Thomsen, MS Thomsen, J Lichota, C Fazakas, I Krizbai, ...
Fluids and Barriers of the CNS 12 (1), 1-14, 2015
Accessing targeted nanoparticles to the brain: The vascular route
A Burkhart, M Azizi, MS Thomsen, LB Thomsen, T Moos
Current medicinal chemistry 21 (36), 4092-4099, 2014
Transfection of primary brain capillary endothelial cells for protein synthesis and secretion of recombinant erythropoietin: a strategy to enable protein delivery to the brain
A Burkhart, TL Andresen, A Aigner, LB Thomsen, T Moos
Cellular and Molecular Life Sciences 74 (13), 2467-2485, 2017
The blood-brain barrier studied in vitro across species
MS Thomsen, N Humle, E Hede, T Moos, A Burkhart, LB Thomsen
PloS one 16 (3), e0236770, 2021
Nanoparticle-derived non-viral genetic transfection at the blood-brain barrier to enable neuronal growth factor delivery by secretion from brain endothelium
L B Thomsen, A B Larsen, J Lichota, T Moos
Current medicinal chemistry 18 (22), 3330-3334, 2011
Gene therapy to the blood–brain barrier with resulting protein secretion as a strategy for treatment of Niemann Picks type C2 disease
E Hede, CB Christiansen, CW Heegaard, T Moos, A Burkhart
Journal of Neurochemistry 156 (3), 290-308, 2021
Epigenetic Regulation of Ferroportin in Primary Cultures of the Rat Blood-Brain Barrier
SS Helgudottir, LJ Routhe, A Burkhart, K Jønsson, IS Pedersen, J Lichota, ...
Molecular neurobiology 57 (8), 3526-3539, 2020
The blood-brain barrier in vitro using primary culture: implications for studies of therapeutic gene expression and iron transport
AB Larsen
River Publishers, 2014
Hepcidin mediates transcriptional changes in ferroportin mRNA in differentiated neuronal-like PC12 cells subjected to iron challenge
SS Helgudottir, J Lichota, A Burkhart, T Moos
Molecular Neurobiology 56 (4), 2362-2374, 2019
Correction to: Hepcidin Mediates Transcriptional Changes in Ferroportin mRNA in Differentiated Neuronal-like PC12 Cells Subjected to Iron Challenge
SS Helgudottir, J Lichota, A Burkhart, T Moos
Molecular Neurobiology 56 (4), 2375-2378, 2019
A novel strategy for delivering Niemann‐Pick type C2 proteins across the blood‐brain barrier using the brain endothelial‐specific AAV‐BR1 virus
CLM Rasmussen, E Hede, LJ Routhe, J Körbelin, SS Helgudottir, ...
Journal of Neurochemistry, 2022
Gene therapy to the blood-brain barrier with resulting protein secretion as a strategy for treatment of NPC2 disease
E Hede, C Heegaard, J Koerbelin, M Schwanninger, T Moos, A Burkhart
Human Gene Therapy 30 (11), A100-A101, 2019
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