Steven Whitebread
Steven Whitebread
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A receptor subtype involved in neuropeptide-Y-induced food intake
C Gerald, MW Walker, L Criscione, EL Gustafson, C Batzl-Hartmann, ...
Nature 382 (6587), 168-171, 1996
Preliminary biochemical characterization of two angiotensin II receptor subtypes
S Whitebread, M Mele, B Kamber, M de Gasparo
Biochemical and biophysical research communications 163 (1), 284-291, 1989
Large-scale prediction and testing of drug activity on side-effect targets
E Lounkine, MJ Keiser, S Whitebread, D Mikhailov, J Hamon, JL Jenkins, ...
Nature 486 (7403), 361-367, 2012
Reducing safety-related drug attrition: the use of in vitro pharmacological profiling
J Bowes, AJ Brown, J Hamon, W Jarolimek, A Sridhar, G Waldron, ...
Nature reviews Drug discovery 11 (12), 909-922, 2012
Three new epoxy-spirolactone derivatives: characterization in vivo and in vitro.
M De Gasparo, U Joss, HP Ramjoue, SE Whitebread, H Haenni, ...
Journal of Pharmacology and Experimental Therapeutics 240 (2), 650-656, 1987
Analysis of pharmacology data and the prediction of adverse drug reactions and off‐target effects from chemical structure
A Bender, J Scheiber, M Glick, JW Davies, K Azzaoui, J Hamon, L Urban, ...
ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 861-873, 2007
Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development
S Whitebread, J Hamon, D Bojanic, L Urban
Drug discovery today 10 (21), 1421-1433, 2005
Pharmacological profile of valsartan: a potent, orally active, nonpeptide antagonist of the angiotensin II AT1‐receptor subtype
L Criscione, M de Gasparo, P Bühlmayer, S Whitebread, HR Ramjoué, ...
British journal of pharmacology 110 (2), 761-771, 1993
Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor.
L Criscione, P Rigollier, C Batzl-Hartmann, H Rüeger, A Stricker-Krongrad, ...
The Journal of clinical investigation 102 (12), 2136-2145, 1998
Inhibition of food intake by neuropeptide Y Y5 receptor antisense oligodeoxynucleotides
AO Schaffhauser, A Stricker-Krongrad, L Brunner, F Cumin, C Gerald, ...
Diabetes 46 (11), 1792-1798, 1997
Mapping adverse drug reactions in chemical space
J Scheiber, JL Jenkins, SCK Sukuru, A Bender, D Mikhailov, M Milik, ...
Journal of medicinal chemistry 52 (9), 3103-3107, 2009
Modeling promiscuity based on in vitro safety pharmacology profiling data
K Azzaoui, J Hamon, B Faller, S Whitebread, E Jacoby, A Bender, ...
ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 874-880, 2007
Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis
J Scheiber, B Chen, M Milik, SCK Sukuru, A Bender, D Mikhailov, ...
Journal of chemical information and modeling 49 (2), 308-317, 2009
Angiotensin II AT2 receptors do not interact with guanine nucleotide binding proteins
SP Bottari, V Taylor, IN King, Y Bogdal, S Whitebread, M de Gasparo
European Journal of Pharmacology: Molecular Pharmacology 207 (2), 157-163, 1991
Ghrelin acts on leptin‐responsive neurones in the rat arcuate nucleus
M Traebert, T Riediger, S Whitebread, E Scharrer, HA Schmid
Journal of neuroendocrinology 14 (7), 580-586, 2002
Valsartan, a potent, orally active angiotensin II antagonist developed from the structurally new amino acid series
P Bühlmayer, P Furet, L Criscione, M de Gasparo, S Whitebread, ...
Bioorganic & Medicinal Chemistry Letters 4 (1), 29-34, 1994
Binding of valsartan to mammalian angiotensin AT1 receptors
M de Gasparo, S Whitebread
Regulatory peptides 59 (3), 303-311, 1995
Biochemical characterization of two angiotensin II receptor subtypes in the rat.
M de Gasparo, S Whitebread, M Mele, AS Motani, PJ Whitcombe, ...
Journal of cardiovascular pharmacology 16, S31-5, 1990
Radioiodinated cgp 42111A: a novel high affinity and highly selective ligand for the characterization of angiotensin AT2 receptors
SE Whitebread, V Taylor, SP Bottari, B Kamber, M de Gasparo
Biochemical and biophysical research communications 181 (3), 1365-1371, 1991
Antialdosterones: incidence and prevention of sexual side effects
M De Gasparo, SE Whitebread, G Preiswerk, X Jeunemaitre, P Corvol, ...
Journal of steroid biochemistry 32 (1), 223-227, 1989
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