Urko M. Marigorta
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Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study
S Kugathasan, LA Denson, TD Walters, MO Kim, UM Marigorta, ...
The Lancet 389 (10080), 1710-1718, 2017
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European
I Olalde, ME Allentoft, F Sánchez-Quinto, G Santpere, CWK Chiang, ...
Nature 507 (7491), 225-228, 2014
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
A Xue, Y Wu, Z Zhu, F Zhang, KE Kemper, Z Zheng, L Yengo, ...
Nature communications 9 (1), 1-14, 2018
Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus
SA Jenks, KS Cashman, E Zumaquero, UM Marigorta, AV Patel, X Wang, ...
Immunity 49 (4), 725-739. e6, 2018
High trans-ethnic replicability of GWAS results implies common causal variants
UM Marigorta, A Navarro
PLoS Genetics 9 (6), e1003566, 2013
Reconstructing the population history of European Romani from genome-wide data
I Mendizabal, O Lao, UM Marigorta, A Wollstein, L Gusmão, V Ferak, ...
Current Biology 22 (24), 2342-2349, 2012
Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease
UM Marigorta, LA Denson, JS Hyams, K Mondal, J Prince, TD Walters, ...
Nature genetics 49 (10), 1517-1521, 2017
Replicability and prediction: lessons and challenges from GWAS
UM Marigorta, JA Rodríguez, G Gibson, A Navarro
Trends in Genetics 34 (7), 504-517, 2018
Copy number variation analysis in the great apes reveals species-specific patterns of structural variation
E Gazave, F Darré, C Morcillo-Suarez, N Petit-Marty, A Carreño, ...
Genome research 21 (10), 1626-1639, 2011
A burden of rare variants associated with extremes of gene expression in human peripheral blood
J Zhao, I Akinsanmi, D Arafat, TJ Cradick, CM Lee, S Banskota, ...
The American Journal of Human Genetics 98 (2), 299-309, 2016
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
E Porcu, S Rüeger, K Lepik, FA Santoni, A Reymond, Z Kutalik
Nature communications 10 (1), 1-12, 2019
Antagonistic pleiotropy and mutation accumulation influence human senescence and disease
JA Rodríguez, UM Marigorta, DA Hughes, N Spataro, E Bosch, A Navarro
Nature Ecology & Evolution 1 (3), 1-5, 2017
Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study
JS Hyams, SD Thomas, N Gotman, Y Haberman, R Karns, M Schirmer, ...
The Lancet 393 (10182), 1708-1720, 2019
Expression quantitative trait locus analysis for translational medicine
G Gibson, JE Powell, UM Marigorta
Genome medicine 7 (1), 1-14, 2015
A simulation study of gene-by-environment interactions in GWAS implies ample hidden effects
UM Marigorta, G Gibson
Frontiers in Genetics, 2014
Combining multiple hypothesis testing with machine learning increases the statistical power of genome-wide association studies
B Mieth, M Kloft, JA Rodríguez, S Sonnenburg, R Vobruba, ...
Scientific reports 6 (1), 1-14, 2016
Blood-derived DNA methylation signatures of Crohn's disease and severity of intestinal inflammation
HK Somineni, S Venkateswaran, V Kilaru, UM Marigorta, A Mo, DT Okou, ...
Gastroenterology 156 (8), 2254-2265. e3, 2019
Adaptive evolution of loci covarying with the human African Pygmy phenotype
I Mendizabal, UM Marigorta, O Lao, D Comas
Human genetics 131 (8), 1305-1317, 2012
Recent human evolution has shaped geographical differences in susceptibility to disease
UM Marigorta, O Lao, F Casals, F Calafell, C Morcillo-Suárez, R Faria, ...
BMC genomics 12 (1), 1-14, 2011
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Articles 1–20