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María Sánchez Osuna
María Sánchez Osuna
The hospital for Sick Children - SickKids
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Metabolic regulation of the epigenome drives lethal infantile ependymoma
KA Michealraj, SA Kumar, LJY Kim, FMG Cavalli, D Przelicki, JB Wojcik, ...
Cell 181 (6), 1329-1345. e24, 2020
902020
PRMT5 inhibition disrupts splicing and stemness in glioblastoma
P Sachamitr, JC Ho, FE Ciamponi, W Ba-Alawi, FJ Coutinho, ...
Nature communications 12 (1), 979, 2021
862021
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
MM Szewczyk, Y Ishikawa, S Organ, N Sakai, F Li, L Halabelian, S Ackloo, ...
Nature communications 11 (1), 2396, 2020
832020
Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease
V Iglesias-Guimarais, E Gil-Guiñon, G Gabernet, M García-Belinchón, ...
Journal of Biological Chemistry 287 (10), 7766-7779, 2012
452012
Chromatin collapse during caspase-dependent apoptotic cell death requires DNA fragmentation factor, 40-kDa subunit-/caspase-activated deoxyribonuclease-mediated 3′-OH single …
V Iglesias-Guimarais, E Gil-Guiñon, M Sánchez-Osuna, E Casanelles, ...
Journal of Biological Chemistry 288 (13), 9200-9215, 2013
382013
Genome-wide screens reveal that resveratrol induces replicative stress in human cells
Y Benslimane, T Bertomeu, J Coulombe-Huntington, M McQuaid, ...
Molecular Cell 79 (5), 846-856. e8, 2020
262020
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition
Y Benslimane, M Sánchez‐Osuna, J Coulombe‐Huntington, T Bertomeu, ...
Aging Cell 20 (4), e13331, 2021
242021
An early and robust activation of caspases heads cells for a regulated form of necrotic-like cell death
M Garcia-Belinchón, M Sánchez-Osuna, L Martínez-Escardó, ...
Journal of Biological Chemistry 290 (34), 20841-20855, 2015
222015
An intrinsic DFF40/CAD endonuclease deficiency impairs oligonucleosomal DNA hydrolysis during caspase-dependent cell death: a common trait in human glioblastoma cells
M Sanchez-Osuna, L Martinez-Escardo, C Granados-Colomina, ...
Neuro-oncology 18 (7), 950-961, 2016
212016
Caspase-activated DNase is necessary and sufficient for oligonucleosomal DNA breakdown, but not for chromatin disassembly during caspase-dependent apoptosis of LN-18 …
M Sánchez-Osuna, M Garcia-Belinchón, V Iglesias-Guimarais, ...
Journal of Biological Chemistry 289 (27), 18752-18769, 2014
202014
NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w
E Casanelles, R Gozzelino, F Marqués-Fernández, V Iglesias-Guimarais, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (5), 1085-1095, 2013
142013
Chemical genetics screen identifies COPB2 tool compounds that alters ER stress response and induces RTK dysregulation in lung cancer cells
P Saraon, J Snider, W Schormann, A Rai, N Radulovich, ...
Journal of Molecular Biology 433 (23), 167294, 2021
72021
AChE for DNA degradation
M Sánchez-Osuna, VJ Yuste
Cell Research 25 (6), 653-654, 2015
32015
Gossypol treatment restores insufficient apoptotic function of DFF40/CAD in human glioblastoma cells
L Martínez-Escardó, M Alemany, M Sánchez-Osuna, A Sánchez-Chardi, ...
Cancers 13 (21), 5579, 2021
22021
Induction of caspase-dependent chromatin disassembly in DFF40/CAD-deficient glioblastoma-derived cells
L Martinez-Escardo, M Sanchez-Osuna, S Besora, J Bruna, VJ Yuste
Cell Death Discovery 5 (Suppl 1), 54, 2019
2019
Identifican el primer marcador bioquímico y molecular del glioblastoma
M Sánchez-Osuna, VJ Yuste
Genética Médica News 3 (46), 22-23, 2016
2016
Study of the intracellular mechanism implicated in the resistance to apoptotic cell death in glioblastoma multiforme
M Sánchez Osuna
Universitat Pompeu Fabra, 2014
2014
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Artikler 1–17