Metabolic regulation of the epigenome drives lethal infantile ependymoma KA Michealraj, SA Kumar, LJY Kim, FMG Cavalli, D Przelicki, JB Wojcik, ... Cell 181 (6), 1329-1345. e24, 2020 | 90 | 2020 |
PRMT5 inhibition disrupts splicing and stemness in glioblastoma P Sachamitr, JC Ho, FE Ciamponi, W Ba-Alawi, FJ Coutinho, ... Nature communications 12 (1), 979, 2021 | 86 | 2021 |
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response MM Szewczyk, Y Ishikawa, S Organ, N Sakai, F Li, L Halabelian, S Ackloo, ... Nature communications 11 (1), 2396, 2020 | 83 | 2020 |
Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease V Iglesias-Guimarais, E Gil-Guiñon, G Gabernet, M García-Belinchón, ... Journal of Biological Chemistry 287 (10), 7766-7779, 2012 | 45 | 2012 |
Chromatin collapse during caspase-dependent apoptotic cell death requires DNA fragmentation factor, 40-kDa subunit-/caspase-activated deoxyribonuclease-mediated 3′-OH single … V Iglesias-Guimarais, E Gil-Guiñon, M Sánchez-Osuna, E Casanelles, ... Journal of Biological Chemistry 288 (13), 9200-9215, 2013 | 38 | 2013 |
Genome-wide screens reveal that resveratrol induces replicative stress in human cells Y Benslimane, T Bertomeu, J Coulombe-Huntington, M McQuaid, ... Molecular Cell 79 (5), 846-856. e8, 2020 | 26 | 2020 |
A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition Y Benslimane, M Sánchez‐Osuna, J Coulombe‐Huntington, T Bertomeu, ... Aging Cell 20 (4), e13331, 2021 | 24 | 2021 |
An early and robust activation of caspases heads cells for a regulated form of necrotic-like cell death M Garcia-Belinchón, M Sánchez-Osuna, L Martínez-Escardó, ... Journal of Biological Chemistry 290 (34), 20841-20855, 2015 | 22 | 2015 |
An intrinsic DFF40/CAD endonuclease deficiency impairs oligonucleosomal DNA hydrolysis during caspase-dependent cell death: a common trait in human glioblastoma cells M Sanchez-Osuna, L Martinez-Escardo, C Granados-Colomina, ... Neuro-oncology 18 (7), 950-961, 2016 | 21 | 2016 |
Caspase-activated DNase is necessary and sufficient for oligonucleosomal DNA breakdown, but not for chromatin disassembly during caspase-dependent apoptosis of LN-18 … M Sánchez-Osuna, M Garcia-Belinchón, V Iglesias-Guimarais, ... Journal of Biological Chemistry 289 (27), 18752-18769, 2014 | 20 | 2014 |
NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w E Casanelles, R Gozzelino, F Marqués-Fernández, V Iglesias-Guimarais, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (5), 1085-1095, 2013 | 14 | 2013 |
Chemical genetics screen identifies COPB2 tool compounds that alters ER stress response and induces RTK dysregulation in lung cancer cells P Saraon, J Snider, W Schormann, A Rai, N Radulovich, ... Journal of Molecular Biology 433 (23), 167294, 2021 | 7 | 2021 |
AChE for DNA degradation M Sánchez-Osuna, VJ Yuste Cell Research 25 (6), 653-654, 2015 | 3 | 2015 |
Gossypol treatment restores insufficient apoptotic function of DFF40/CAD in human glioblastoma cells L Martínez-Escardó, M Alemany, M Sánchez-Osuna, A Sánchez-Chardi, ... Cancers 13 (21), 5579, 2021 | 2 | 2021 |
Induction of caspase-dependent chromatin disassembly in DFF40/CAD-deficient glioblastoma-derived cells L Martinez-Escardo, M Sanchez-Osuna, S Besora, J Bruna, VJ Yuste Cell Death Discovery 5 (Suppl 1), 54, 2019 | | 2019 |
Identifican el primer marcador bioquímico y molecular del glioblastoma M Sánchez-Osuna, VJ Yuste Genética Médica News 3 (46), 22-23, 2016 | | 2016 |
Study of the intracellular mechanism implicated in the resistance to apoptotic cell death in glioblastoma multiforme M Sánchez Osuna Universitat Pompeu Fabra, 2014 | | 2014 |