Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers. S Meri, BP Morgan, A Davies, RH Daniels, MG Olavesen, H Waldmann, ... Immunology 71 (1), 1, 1990 | 600 | 1990 |
Discrimination between activators and nonactivators of the alternative pathway of complement: regulation via a sialic acid/polyanion binding site on factor H. S Meri, MK Pangburn Proceedings of the National Academy of Sciences 87 (10), 3982-3986, 1990 | 468 | 1990 |
Membranoproliferative glomerulonephritis type II (dense deposit disease): an update GB Appel, HT Cook, G Hageman, JC Jennette, M Kashgarian, ... Journal of the American Society of Nephrology 16 (5), 1392-1403, 2005 | 446 | 2005 |
The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi J Hellwage, T Meri, T Heikkilä, A Alitalo, J Panelius, P Lahdenne, ... Journal of Biological Chemistry 276 (11), 8427-8435, 2001 | 415 | 2001 |
Complement activation after oxidative stress: role of the lectin complement pathway CD Collard, A Väkevä, MA Morrissey, A Agah, SA Rollins, WR Reenstra, ... The American journal of pathology 156 (5), 1549-1556, 2000 | 404 | 2000 |
Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome T Manuelian, J Hellwage, S Meri, J Caprioli, M Noris, S Heinen, M Jozsi, ... The Journal of clinical investigation 111 (8), 1181-1190, 2003 | 376 | 2003 |
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation MK Liszewski, M Kolev, G Le Friec, M Leung, PG Bertram, AF Fara, ... Immunity 39 (6), 1143-1157, 2013 | 310 | 2013 |
Rituximab (anti-CD20) therapy of B-cell lymphomas: direct complement killing is superior to cellular effector mechanisms. A Harjunpää, S Junnikkala, S Meri Scandinavian journal of immunology 51 (6), 634-641, 2000 | 309 | 2000 |
Molecular genetic characterization of the Fennoscandian cervid strain, a new genotypic group (G10) of Echinococcus granulosus A Lavikainen, MJ Lehtinen, T Meri, V Hirvelä-Koski, S Meri Parasitology 127 (3), 207-215, 2003 | 282 | 2003 |
Colloquium: Structure-Function Studies of the Complement System-Factor H family proteins: on complement, microbes and human diseases PF Zipfiel, C Skerka, J Hellwage, ST Jokiranta, S Meri, V Brade, P Kraiczy, ... Biochemical Society Transactions 30 (6), 971-977, 2002 | 277 | 2002 |
Membrane proteins that protect against complement lysis BP Morgan, S Meri Springer seminars in immunopathology 15 (4), 369-396, 1994 | 276 | 1994 |
Immune evasion of tumor cells using membrane-bound complement regulatory proteins A Gorter, S Meri Immunology today 20 (12), 576-582, 1999 | 271 | 1999 |
Each of the three binding sites on complement factor H interacts with a distinct site on C3b TS Jokiranta, J Hellwage, V Koistinen, PF Zipfel, S Meri Journal of Biological Chemistry 275 (36), 27657-27662, 2000 | 269 | 2000 |
New approaches to the treatment of dense deposit disease RJH Smith, J Alexander, PN Barlow, M Botto, TL Cassavant, HT Cook, ... Journal of the American Society of Nephrology 18 (9), 2447-2456, 2007 | 267 | 2007 |
Factor H family proteins: on complement, microbes and human diseases PF Zipfel, C Skerka, J Hellwage, ST Jokiranta, S Meri, V Brade, P Kraiczy, ... Biochemical Society Transactions 30 (6), 971-978, 2002 | 260 | 2002 |
Y402H polymorphism of complement factor H affects binding affinity to C-reactive protein M Laine, H Jarva, S Seitsonen, K Haapasalo, MJ Lehtinen, N Lindeman, ... The Journal of Immunology 178 (6), 3831-3836, 2007 | 249 | 2007 |
The factor H protein family PF Zipfel, TS Jokiranta, J Hellwage, V Koistinen, S Meri Immunopharmacology 42 (1-3), 53-60, 1999 | 233 | 1999 |
Extended haplotypes in the complement factor H (CFH) and CFH‐related (CFHR) family of genes protect against age‐related macular degeneration … GS Hageman, LS Hancox, AJ Taiber, KM Gehrs, DH Anderson, ... Annals of medicine 38 (8), 592-604, 2006 | 227 | 2006 |
Localization of the heparin-binding site on complement factor H. MK Pangburn, MA Atkinson, S Meri Journal of Biological Chemistry 266 (25), 16847-16853, 1991 | 223 | 1991 |
IFN-α enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression J Tissari, J Sirén, S Meri, I Julkunen, S Matikainen The Journal of Immunology 174 (7), 4289-4294, 2005 | 218 | 2005 |