| Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture CK Savile, JM Janey, EC Mundorff, JC Moore, S Tam, WR Jarvis, ... Science 329 (5989), 305-309, 2010 | 1869 | 2010 |
| Improving catalytic function by ProSAR-driven enzyme evolution RJ Fox, SC Davis, EC Mundorff, LM Newman, V Gavrilovic, SK Ma, ... Nature biotechnology 25 (3), 338-344, 2007 | 666 | 2007 |
| Synthetic shuffling expands functional protein diversity by allowing amino acids to recombine independently JE Ness, S Kim, A Gottman, R Pak, A Krebber, TV Borchert, ... Nature biotechnology 20 (12), 1251-1255, 2002 | 288 | 2002 |
| Development of a biocatalytic process as an alternative to the (−)-DIP-Cl-mediated asymmetric reduction of a key intermediate of montelukast J Liang, J Lalonde, B Borup, V Mitchell, E Mundorff, N Trinh, ... Organic Process Research & Development 14 (1), 193-198, 2010 | 260 | 2010 |
| Evolutionary potential of (β/α) 8-barrels: functional promiscuity produced by single substitutions in the enolase superfamily DMZ Schmidt, EC Mundorff, M Dojka, E Bermudez, JE Ness, ... Biochemistry 42 (28), 8387-8393, 2003 | 229 | 2003 |
| Highly Enantioselective Reduction of a Small Heterocyclic Ketone: Biocatalytic Reduction of Tetrahydrothiophene-3-one to the Corresponding (R)-Alcohol J Liang, E Mundorff, R Voladri, S Jenne, L Gilson, A Conway, A Krebber, ... Organic Process Research & Development 14 (1), 188-192, 2010 | 140 | 2010 |
| Optimization of crossover points for directed evolution EC Mundorff, S Govindarajan, C Gustafsson, JS Minshull US Patent 7,620,500, 2009 | 115 | 2009 |
| The interplay between binding energy and catalysis in the evolution of a catalytic antibody HD Ulrich, E Mundorff, BD Santarsiero, EM Driggers, RC Stevens, ... Nature 389 (6648), 271-275, 1997 | 114 | 1997 |
| Ketoreductase polypeptides for the production of azetidinone O Campopiano, E Mundorff, B Borup, R Voladri US Patent 7,883,879, 2011 | 99 | 2011 |
| Ketoreductase polypeptides for the reduction of acetophenones J Liang, SJ Jenne, E Mundorff, C Ching, JM Gruber, A Krebber, ... US Patent 8,748,143, 2014 | 93 | 2014 |
| Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane J Liang, SJ Jenne, E Mundorff, R Voladri, J Lalonde, G Huisman US Patent 7,977,078, 2011 | 93* | 2011 |
| Ketoreductase polypeptides for the production of (R)-3-hydroxythiolane J Liang, SJ Jenne, E Mundorff, R Voladri, J Lalonde, G Huisman US Patent 7,977,078, 2011 | 93 | 2011 |
| Ketoreductases and uses thereof C Ching, JM Gruber, GW Huisman, E Mundorff, LM Newman US Patent 7,820,421, 2010 | 90 | 2010 |
| A comparative analysis of the immunological evolution of antibody 28B4 J Yin, EC Mundorff, PL Yang, KU Wendt, D Hanway, RC Stevens, ... Biochemistry 40 (36), 10764-10773, 2001 | 90 | 2001 |
| Ketoreductase enzymes and uses thereof LJ Giver, LM Newman, E Mundorff, GW Huisman, SJ Jenne, J Zhu, ... US Patent 7,879,585, 2011 | 88 | 2011 |
| Ketoreductase enzymes and uses thereof LJ Giver, LM Newman, E Mundorff, GW Huisman, SJ Jenne, J Zhu, ... US Patent 7,879,585, 2011 | 88 | 2011 |
| Ketoreductase enzymes and uses thereof LJ Giver, LM Newman, E Mundorff, GW Huisman, SJ Jenne, J Zhu, ... US Patent 7,879,585, 2011 | 88 | 2011 |
| Ketoreductases for the production of (S, E)-methyl 2-(3-(3-(2-(7-chloroquinolin-2-yl) vinyl) phenyl)-3-hroxypropyl) benzoate J Liang, B Borup, V Mitchell, E Mundorff, J Lalonde, GW Huisman US Patent 8,088,610, 2012 | 82 | 2012 |
| Ketoreductase polypeptides for the stereoselective production of (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1, 3-oxazolidin-2-one E Mundorff, E De Vries US Patent 8,273,554, 2012 | 80 | 2012 |
| Development of a Practical Biocatalytic Process for (R)-2-Methylpentanol OW Gooding, R Voladri, A Bautista, T Hopkins, G Huisman, S Jenne, ... Organic Process Research & Development 14 (1), 119-126, 2010 | 66 | 2010 |
