| TGR5-mediated bile acid sensing controls glucose homeostasis C Thomas, A Gioiello, L Noriega, A Strehle, J Oury, G Rizzo, ... Cell metabolism 10 (3), 167-177, 2009 | 1866 | 2009 |
| The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis S Fiorucci, E Antonelli, A Mencarelli, S Orlandi, B Renga, G Rizzo, ... Hepatology 42 (3), 539-548, 2005 | 630 | 2005 |
| TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading TWH Pols, M Nomura, T Harach, GL Sasso, MH Oosterveer, C Thomas, ... Cell metabolism 14 (6), 747-757, 2011 | 553 | 2011 |
| Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs S Fiorucci, E Antonelli, E Distrutti, G Rizzo, A Mencarelli, S Orlandi, ... Gastroenterology 129 (4), 1210-1224, 2005 | 531 | 2005 |
| The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis S Fiorucci, E Antonelli, G Rizzo, B Renga, A Mencarelli, L Riccardi, ... Gastroenterology 127 (5), 1497-1512, 2004 | 499 | 2004 |
| Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane: retention of caveolin-2 at the level of the golgi complex I Parolini, M Sargiacomo, F Galbiati, G Rizzo, F Grignani, JA Engelman, ... Journal of Biological Chemistry 274 (36), 25718-25725, 1999 | 278 | 1999 |
| Targeting farnesoid X receptor for liver and metabolic disorders S Fiorucci, G Rizzo, A Donini, E Distrutti, L Santucci Trends in molecular medicine 13 (7), 298-309, 2007 | 236 | 2007 |
| Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor γ contributes to the antifibrotic activity of FXR ligands in rodent models of liver … S Fiorucci, G Rizzo, E Antonelli, B Renga, A Mencarelli, L Riccardi, ... Journal of Pharmacology and Experimental Therapeutics 315 (1), 58-68, 2005 | 220 | 2005 |
| A farnesoid x receptor-small heterodimer partner regulatory cascade modulates tissue metalloproteinase inhibitor-1 and matrix metalloprotease expression in hepatic stellate … S Fiorucci, G Rizzo, E Antonelli, B Renga, A Mencarelli, L Riccardi, ... Journal of Pharmacology and Experimental Therapeutics 314 (2), 584-595, 2005 | 220 | 2005 |
| Functional characterization of the semisynthetic bile acid derivative INT-767, a dual farnesoid X receptor and TGR5 agonist G Rizzo, D Passeri, F De Franco, G Ciaccioli, L Donadio, G Rizzo, ... Molecular pharmacology 78 (4), 617-630, 2010 | 209 | 2010 |
| The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo G Rizzo, M Disante, A Mencarelli, B Renga, A Gioiello, R Pellicciari, ... Molecular pharmacology 70 (4), 1164-1173, 2006 | 201 | 2006 |
| A β-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction S Fiorucci, JL Wallace, A Mencarelli, E Distrutti, G Rizzo, S Farneti, ... Proceedings of the National Academy of Sciences 101 (44), 15736-15741, 2004 | 194 | 2004 |
| PPARs and other nuclear receptors in inflammation G Rizzo, S Fiorucci Current opinion in pharmacology 6 (4), 421-427, 2006 | 174 | 2006 |
| Role of FXR in regulating bile acid homeostasis and relevance for human diseases G Rizzo, B Renga, A Mencarelli, R Pellicciari, S Fiorucci Current Drug Targets-Immune, Endocrine & Metabolic Disorders 5 (3), 289-303, 2005 | 148 | 2005 |
| A role for proteinase-activated receptor–1 in inflammatory bowel diseases N Vergnolle, L Cellars, A Mencarelli, G Rizzo, S Swaminathan, P Beck, ... The Journal of clinical investigation 114 (10), 1444-1456, 2004 | 122 | 2004 |
| The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes G Rizzo, B Renga, E Antonelli, D Passeri, R Pellicciari, S Fiorucci Molecular pharmacology 68 (2), 551-558, 2005 | 105 | 2005 |
| DNA hypomethylation and histone variant macroH2A1 synergistically attenuate chemotherapy-induced senescence to promote hepatocellular carcinoma progression M Borghesan, C Fusilli, F Rappa, C Panebianco, G Rizzo, JA Oben, ... Cancer research 76 (3), 594-606, 2016 | 78 | 2016 |
| Btg2 enhances retinoic acid-induced differentiation by modulating histone H4 methylation and acetylation D Passeri, A Marcucci, G Rizzo, M Billi, M Panigada, L Leonardi, F Tirone, ... Molecular and cellular biology 26 (13), 5023-5032, 2006 | 73 | 2006 |
| Back door modulation of the farnesoid X receptor: design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives R Pellicciari, A Gioiello, G Costantino, BM Sadeghpour, G Rizzo, U Meyer, ... Journal of medicinal chemistry 49 (14), 4208-4215, 2006 | 67 | 2006 |
| Extending SAR of bile acids as FXR ligands: Discovery of 23-N-(carbocinnamyloxy)-3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-amine A Gioiello, A Macchiarulo, A Carotti, P Filipponi, G Costantino, G Rizzo, ... Bioorganic & medicinal chemistry 19 (8), 2650-2658, 2011 | 66 | 2011 |
