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michael milsom
michael milsom
German Cancer Research Center (DKFZ) & Heidelberg Institute for Stem Cell Technology and
Verificeret mail på hi-stem.de - Startside
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Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
D Walter, A Lier, A Geiselhart, FB Thalheimer, S Huntscha, MC Sobotta, ...
Nature 520 (7548), 549-552, 2015
6212015
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ...
Cell stem cell 15 (4), 507-522, 2014
5552014
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ...
Cell stem cell 17 (4), 422-434, 2015
4242015
Causes and consequences of hematopoietic stem cell heterogeneity
S Haas, A Trumpp, MD Milsom
Cell stem cell 22 (5), 627-638, 2018
3182018
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
M Malehmir, D Pfister, S Gallage, M Szydlowska, D Inverso, E Kotsiliti, ...
Nature medicine 25 (4), 641-655, 2019
3072019
Somatic mutation rates scale with lifespan across mammals
A Cagan, A Baez-Ortega, N Brzozowska, F Abascal, THH Coorens, ...
Nature 604 (7906), 517-524, 2022
2482022
Requirement for CDK6 in MLL-rearranged acute myeloid leukemia
T Placke, K Faber, A Nonami, SL Putwain, HR Salih, FH Heidel, A Krämer, ...
Blood, The Journal of the American Society of Hematology 124 (1), 13-23, 2014
2102014
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype
C Brendel, S Guda, R Renella, DE Bauer, MC Canver, YJ Kim, ...
The Journal of clinical investigation 126 (10), 3868-3878, 2016
1652016
Overcoming reprogramming resistance of Fanconi anemia cells
LUW Müller, MD Milsom, CE Harris, R Vyas, KM Brumme, K Parmar, ...
Blood, The Journal of the American Society of Hematology 119 (23), 5449-5457, 2012
1592012
Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI
D Chinnasamy, MD Milsom, J Shaffer, J Neuenfeldt, AF Shaaban, ...
Virology Journal 3 (1), 1-16, 2006
1412006
miRNA-embedded shRNAs for lineage-specific BCL11A knockdown and hemoglobin F induction
S Guda, C Brendel, R Renella, P Du, DE Bauer, MC Canver, JK Grenier, ...
Molecular Therapy 23 (9), 1465-1474, 2015
1332015
Haematopoietic stem cells in perisinusoidal niches are protected from ageing
M Saçma, J Pospiech, R Bogeska, W de Back, JP Mallm, V Sakk, K Soller, ...
Nature cell biology 21 (11), 1309-1320, 2019
1012019
The European hematology association roadmap for European hematology research: a consensus document
A Engert, C Balduini, A Brand, B Coiffier, C Cordonnier, H Döhner, ...
haematologica 101 (2), 115, 2016
902016
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging
R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ...
Cell Stem Cell 29 (8), 1273-1284. e8, 2022
832022
Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells
G Ghiaur, MJ Ferkowicz, MD Milsom, J Bailey, D Witte, JA Cancelas, ...
Blood, The Journal of the American Society of Hematology 111 (7), 3313-3321, 2008
692008
RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia
S Rudat, A Pfaus, YY Cheng, J Holtmann, JM Ellegast, C Buehler, ...
Leukemia 32 (10), 2189-2202, 2018
642018
Stem cell-specific mechanisms ensure genomic fidelity within HSCs and upon aging of HSCs
BM Moehrle, K Nattamai, A Brown, MC Florian, M Ryan, M Vogel, ...
Cell reports 13 (11), 2412-2424, 2015
592015
Rapid lentiviral transduction preserves the engraftment potential of Fanca−/− hematopoietic stem cells
LUW Müller, MD Milsom, MO Kim, A Schambach, T Schuesler, ...
Molecular Therapy 16 (6), 1154-1160, 2008
562008
EDA-fibronectin originating from osteoblasts inhibits the immune response against cancer
S Rossnagl, E Altrock, C Sens, S Kraft, K Rau, MD Milsom, T Giese, ...
PLoS biology 14 (9), e1002562, 2016
472016
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia
M Sonnet, R Claus, N Becker, M Zucknick, J Petersen, DB Lipka, ...
Genome medicine 6 (4), 1-16, 2014
462014
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Artikler 1–20