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michael milsom
michael milsom
German Cancer Research Center (DKFZ) & Heidelberg Institute for Stem Cell Technology and
Verificeret mail på hi-stem.de - Startside
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Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells
D Walter, A Lier, A Geiselhart, FB Thalheimer, S Huntscha, MC Sobotta, ...
Nature 520 (7548), 549-552, 2015
6762015
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ...
Cell stem cell 15 (4), 507-522, 2014
6032014
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ...
Cell stem cell 17 (4), 422-434, 2015
4702015
Causes and consequences of hematopoietic stem cell heterogeneity
S Haas, A Trumpp, MD Milsom
Cell stem cell 22 (5), 627-638, 2018
3682018
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
M Malehmir, D Pfister, S Gallage, M Szydlowska, D Inverso, E Kotsiliti, ...
Nature medicine 25 (4), 641-655, 2019
3462019
Somatic mutation rates scale with lifespan across mammals
A Cagan, A Baez-Ortega, N Brzozowska, F Abascal, THH Coorens, ...
Nature 604 (7906), 517-524, 2022
3312022
Requirement for CDK6 in MLL-rearranged acute myeloid leukemia
T Placke, K Faber, A Nonami, SL Putwain, HR Salih, FH Heidel, A Krämer, ...
Blood, The Journal of the American Society of Hematology 124 (1), 13-23, 2014
2212014
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype
C Brendel, S Guda, R Renella, DE Bauer, MC Canver, YJ Kim, ...
The Journal of clinical investigation 126 (10), 3868-3878, 2016
1832016
Overcoming reprogramming resistance of Fanconi anemia cells
LUW Müller, MD Milsom, CE Harris, R Vyas, KM Brumme, K Parmar, ...
Blood, The Journal of the American Society of Hematology 119 (23), 5449-5457, 2012
1632012
Multicistronic lentiviral vectors containing the FMDV 2A cleavage factor demonstrate robust expression of encoded genes at limiting MOI
D Chinnasamy, MD Milsom, J Shaffer, J Neuenfeldt, AF Shaaban, ...
Virology Journal 3, 1-16, 2006
1432006
miRNA-embedded shRNAs for lineage-specific BCL11A knockdown and hemoglobin F induction
S Guda, C Brendel, R Renella, P Du, DE Bauer, MC Canver, JK Grenier, ...
Molecular Therapy 23 (9), 1465-1474, 2015
1382015
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging
R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ...
Cell stem cell 29 (8), 1273-1284. e8, 2022
1342022
Haematopoietic stem cells in perisinusoidal niches are protected from ageing
M Saçma, J Pospiech, R Bogeska, W de Back, JP Mallm, V Sakk, K Soller, ...
Nature cell biology 21 (11), 1309-1320, 2019
1262019
The European hematology association roadmap for European hematology research: a consensus document
A Engert, C Balduini, A Brand, B Coiffier, C Cordonnier, H Döhner, ...
haematologica 101 (2), 115, 2016
952016
Rac1 is essential for intraembryonic hematopoiesis and for the initial seeding of fetal liver with definitive hematopoietic progenitor cells
G Ghiaur, MJ Ferkowicz, MD Milsom, J Bailey, D Witte, JA Cancelas, ...
Blood, The Journal of the American Society of Hematology 111 (7), 3313-3321, 2008
732008
RET-mediated autophagy suppression as targetable co-dependence in acute myeloid leukemia
S Rudat, A Pfaus, YY Cheng, J Holtmann, JM Ellegast, C Buehler, ...
Leukemia 32 (10), 2189-2202, 2018
692018
Stem cell-specific mechanisms ensure genomic fidelity within HSCs and upon aging of HSCs
BM Moehrle, K Nattamai, A Brown, MC Florian, M Ryan, M Vogel, ...
Cell reports 13 (11), 2412-2424, 2015
652015
Rapid lentiviral transduction preserves the engraftment potential of Fanca−/− hematopoietic stem cells
LUW Müller, MD Milsom, MO Kim, A Schambach, T Schuesler, ...
Molecular Therapy 16 (6), 1154-1160, 2008
552008
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
P Hernández-Malmierca, D Vonficht, A Schnell, HJ Uckelmann, ...
Cell Stem Cell 29 (5), 760-775. e10, 2022
512022
Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response
M Scheller, AK Ludwig, S Göllner, C Rohde, S Krämer, S Stäble, ...
Nature Cancer 2 (5), 527-544, 2021
502021
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