|Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization|
DW Roberts, G Patlewicz, PS Kern, F Gerberick, I Kimber, RJ Dearman, ...
Chemical research in toxicology 20 (7), 1019-1030, 2007
|Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships: The report and recommendations of ecvam workshop 52|
TI Netzeva, AP Worth, T Aldenberg, R Benigni, MTD Cronin, P Gramatica, ...
Alternatives to Laboratory Animals 33 (2), 155-173, 2005
|The CompTox Chemistry Dashboard: a community data resource for environmental chemistry|
AJ Williams, CM Grulke, J Edwards, AD McEachran, K Mansouri, ...
Journal of cheminformatics 9, 1-27, 2017
|Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods|
FG Gerberick, CA Ryan, PS Kern, H Schlatter, RJ Dearman, I Kimber, ...
Derm 16 (4), 157-202, 2005
|ToxCast chemical landscape: paving the road to 21st century toxicology|
AM Richard, RS Judson, KA Houck, CM Grulke, P Volarath, ...
Chemical research in toxicology 29 (8), 1225-1251, 2016
|An evaluation of the implementation of the Cramer classification scheme in the Toxtree software|
G Patlewicz, N Jeliazkova, RJ Safford, AP Worth, B Aleksiev
SAR and QSAR in Environmental Research 19 (5-6), 495-524, 2008
|Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA)|
KE Tollefsen, S Scholz, MT Cronin, SW Edwards, J de Knecht, K Crofton, ...
Regulatory Toxicology and Pharmacology 70 (3), 629-640, 2014
|A stepwise approach for defining the applicability domain of SAR and QSAR models|
S Dimitrov, G Dimitrova, T Pavlov, N Dimitrova, G Patlewicz, J Niemela, ...
Journal of chemical information and modeling 45 (4), 839-849, 2005
|A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing|
D Basketter, H Clewell, I Kimber, A Rossi, B Blaauboer, R Burrier, ...
|Skin sensitization: reaction mechanistic applicability domains for structure− activity relationships|
AO Aptula, G Patlewicz, DW Roberts
Chemical Research in Toxicology 18 (9), 1420-1426, 2005
|The next generation blueprint of computational toxicology at the US Environmental Protection Agency|
RS Thomas, T Bahadori, TJ Buckley, J Cowden, C Deisenroth, ...
Toxicological Sciences 169 (2), 317-332, 2019
|The role of the European Chemicals Bureau in promoting the regulatory use of (Q) SAR methods|
AP Worth, A Bassan, J De Bruijn, A Gallegos Saliner, T Netzeva, M Pavan, ...
SAR and QSAR in Environmental Research 18 (1-2), 111-125, 2007
|T4 report: Toward good read-across practice (GRAP) guidance|
N Ball, MTD Cronin, J Shen, K Blackburn, ED Booth, M Bouhifd, E Donley, ...
Altex 33 (2), 149, 2016
|Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse …|
DW Roberts, AO Aptula, G Patlewicz
Chemical Research in Toxicology 20 (1), 44-60, 2007
|In silico toxicology protocols|
GJ Myatt, E Ahlberg, Y Akahori, D Allen, A Amberg, LT Anger, A Aptula, ...
Regulatory Toxicology and Pharmacology 96, 1-17, 2018
|A chemical dataset for evaluation of alternative approaches to skin‐sensitization testing|
GF Gerberick, CA Ryan, PS Kern, RJ Dearman, I Kimber, GY Patlewicz, ...
Contact dermatitis 50 (5), 274-288, 2004
|Ranking of hair dye substances according to predicted sensitization potency: quantitative structure–activity relationships|
H Søsted, DA Basketter, E Estrada, JD Johansen, GY Patlewicz
Contact Dermatitis 51 (5‐6), 241-254, 2004
|Mechanistic applicability domains for non-animal based prediction of toxicological endpoints. QSAR analysis of the Schiff base applicability domain for skin sensitization|
DW Roberts, AO Aptula, G Patlewicz
Chemical research in toxicology 19 (9), 1228-1233, 2006
|Use of category approaches, read-across and (Q) SAR: general considerations|
G Patlewicz, N Ball, ED Booth, E Hulzebos, E Zvinavashe, C Hennes
Regulatory Toxicology and Pharmacology 67 (1), 1-12, 2013
|Non-enzymatic glutathione reactivity and in vitro toxicity: a non-animal approach to skin sensitization|
AO Aptula, G Patlewicz, DW Roberts, TW Schultz
Toxicology in vitro 20 (2), 239-247, 2006