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Jakob Fuhrmann
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Chemical biology of protein arginine modifications in epigenetic regulation
J Fuhrmann, KW Clancy, PR Thompson
Chemical reviews 115 (11), 5413-5461, 2015
2812015
McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR
J Fuhrmann, A Schmidt, S Spiess, A Lehner, K Turgay, K Mechtler, ...
Science 324 (5932), 1323-1327, 2009
1842009
Modulation of ADAMTS13 secretion and specific activity by a combination of common amino acid polymorphisms and a missense mutation
B Plaimauer, J Fuhrmann, G Mohr, W Wernhart, K Bruno, S Ferrari, ...
Blood 107 (1), 118-125, 2006
1232006
Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response
A Schmidt, DB Trentini, S Spiess, J Fuhrmann, G Ammerer, K Mechtler, ...
Molecular & Cellular Proteomics 13 (2), 537-550, 2014
1122014
Ebselen, a small-molecule capsid inhibitor of HIV-1 replication
S Thenin-Houssier, IMS De Vera, L Pedro-Rosa, A Brady, A Richard, ...
Antimicrobial agents and chemotherapy 60 (4), 2195-2208, 2016
1112016
Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design
DJ Slade, P Fang, CJ Dreyton, Y Zhang, J Fuhrmann, D Rempel, BD Bax, ...
ACS chemical biology 10 (4), 1043-1053, 2015
1082015
Protein arginine methylation and citrullination in epigenetic regulation
J Fuhrmann, PR Thompson
ACS chemical biology 11 (3), 654-668, 2016
1072016
S-nitrosylation of microtubule-associated protein 1B mediates nitric-oxide-induced axon retraction
H Stroissnigg, A Trančíková, L Descovich, J Fuhrmann, W Kutschera, ...
Nature cell biology 9 (9), 1035-1045, 2007
862007
Chemical and biological methods to detect post‐translational modifications of arginine
DJ Slade, V Subramanian, J Fuhrmann, PR Thompson
Biopolymers 101 (2), 133-143, 2014
762014
Identification of a binding site for unsaturated fatty acids in the orphan nuclear receptor Nurr1
IMS de Vera, PK Giri, P Munoz-Tello, R Brust, J Fuhrmann, ...
ACS chemical biology 11 (7), 1795-1799, 2016
642016
Defining a conformational ensemble that directs activation of PPARγ
IM Chrisman, MD Nemetchek, IMS De Vera, J Shang, Z Heidari, Y Long, ...
Nature communications 9 (1), 1794, 2018
622018
A structural mechanism for directing corepressor-selective inverse agonism of PPARγ
R Brust, J Shang, J Fuhrmann, SA Mosure, J Bass, A Cano, Z Heidari, ...
Nature communications 9 (1), 4687, 2018
552018
Chasing phosphoarginine proteins: development of a selective enrichment method using a phosphatase trap
DB Trentini, J Fuhrmann, K Mechtler, T Clausen
Molecular & Cellular Proteomics 13 (8), 1953-1964, 2014
522014
Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion
M Wang, J Fuhrmann, PR Thompson
Biochemistry 53 (50), 7884-7892, 2014
502014
Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria
J Fuhrmann, B Mierzwa, DB Trentini, S Spiess, A Lehner, E Charpentier, ...
Cell reports 3 (6), 1832-1839, 2013
492013
Modification of the orthosteric PPARγ covalent antagonist scaffold yields an improved dual-site allosteric inhibitor
R Brust, H Lin, J Fuhrmann, A Asteian, TM Kamenecka, DJ Kojetin
ACS chemical biology 12 (4), 969-978, 2017
422017
Synthesis and Use of a Phosphonate Amidine to Generate an Anti‐Phosphoarginine‐Specific Antibody
J Fuhrmann, V Subramanian, PR Thompson
Angewandte Chemie 127 (49), 14928-14931, 2015
422015
Activity-based profiling reveals a regulatory link between oxidative stress and protein arginine phosphorylation
J Fuhrmann, V Subramanian, DJ Kojetin, PR Thompson
Cell chemical biology 23 (8), 967-977, 2016
402016
Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl …
TS Hughes, J Shang, R Brust, IMS de Vera, J Fuhrmann, C Ruiz, ...
Journal of medicinal chemistry 59 (22), 10335-10341, 2016
232016
Cyanopyrrolidine inhibitors of ubiquitin specific protease 7 mediate desulfhydration of the active-site cysteine
C Bashore, P Jaishankar, NJ Skelton, J Fuhrmann, BR Hearn, PS Liu, ...
ACS Chemical Biology 15 (6), 1392-1400, 2020
222020
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