| Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation T Afroz, EM Hock, P Ernst, C Foglieni, M Jambeau, LAB Gilhespy, ... Nature communications 8 (1), 45, 2017 | 270 | 2017 |
| TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates F Laferrière, Z Maniecka, M Pérez-Berlanga, M Hruska-Plochan, ... Nature neuroscience 22 (1), 65-77, 2019 | 149 | 2019 |
| Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics F Laferrière, P Tixador, M Moudjou, J Chapuis, P Sibille, L Herzog, ... PLoS pathogens 9 (10), e1003702, 2013 | 68 | 2013 |
| Targeting α-Synuclein for PD Therapeutics: A Pursuit on All Fronts M Teil, ML Arotcarena, E Faggiani, F Laferriere, E Bezard, B Dehay Biomolecules 10 (3), 391, 2020 | 56 | 2020 |
| Advances and challenges in understanding the multifaceted pathogenesis of amyotrophic lateral sclerosis F Laferriere, M Polymenidou Swiss medical weekly, 2015 | 56 | 2015 |
| Hypertonic stress causes cytoplasmic translocation of neuronal, but not astrocytic, FUS due to impaired transportin function EM Hock, Z Maniecka, M Hruska-Plochan, S Reber, F Laferrière, SS MK, ... Cell reports 24 (4), 987-1000. e7, 2018 | 54 | 2018 |
| Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification M Moudjou, P Sibille, G Fichet, F Reine, J Chapuis, L Herzog, E Jaumain, ... MBio 5 (1), 10.1128/mbio. 00829-13, 2014 | 54 | 2014 |
| Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons F De Giorgi, F Laferrière, F Zinghirino, E Faggiani, A Lends, M Bertoni, ... Science Advances 6 (40), eabc4364, 2020 | 50 | 2020 |
| Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates M Bourdenx, A Nioche, S Dovero, ML Arotcarena, S Camus, G Porras, ... Science advances 6 (20), eaaz9165, 2020 | 38 | 2020 |
| Memory decline and its reversal in aging and neurodegeneration involve miR-183/96/182 biogenesis A Jawaid, BT Woldemichael, EA Kremer, F Laferriere, N Gaur, T Afroz, ... Molecular neurobiology 56, 3451-3462, 2019 | 35 | 2019 |
| Similar neuronal imprint and no cross-seeded fibrils in α-synuclein aggregates from MSA and Parkinson’s disease F Laferrière, S Claverol, E Bezard, F De Giorgi, F Ichas npj Parkinson's Disease 8 (1), 10, 2022 | 16 | 2022 |
| Early stage prion assembly involves two subpopulations with different quaternary structures and a secondary templating pathway A Igel-Egalon, F Laferrière, M Moudjou, J Bohl, M Mezache, T Knäpple, ... Communications biology 2 (1), 363, 2019 | 16 | 2019 |
| Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy F Laferrière, X He, F Zinghirino, E Doudnikoff, E Faggiani, WG Meissner, ... Cells 9 (11), 2371, 2020 | 15 | 2020 |
| Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD M Hruska-Plochan, KM Betz, S Ronchi, VI Wiersma, Z Maniecka, EM Hock, ... bioRxiv, 2021.12. 08.471089, 2021 | 12 | 2021 |
| Crossing species barriers relies on structurally distinct prion assemblies and their complementation A Igel-Egalon, F Laferrière, P Tixador, M Moudjou, L Herzog, F Reine, ... Molecular Neurobiology 57, 2572-2587, 2020 | 12 | 2020 |
| Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation. Nat Commun 8: 45 T Afroz, EM Hock, P Ernst, C Foglieni, M Jambeau, L Gilhespy, ... | 10 | 2017 |
| SarkoSpin: a technique for biochemical isolation and characterization of pathological TDP-43 aggregates M Pérez-Berlanga, F Laferrière, M Polymenidou Bio-protocol 9 (22), e3424-e3424, 2019 | 8 | 2019 |
| Neurons with Cat’s Eyes: A Synthetic Strain of α-Synuclein Fibrils Seeding Neuronal Intranuclear Inclusions F De Giorgi, MB Abdul-Shukkoor, M Kashyrina, LA Largitte, F De Nuccio, ... Biomolecules 12 (3), 436, 2022 | 7 | 2022 |
| Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein H Leske, S Hornemann, US Herrmann, C Zhu, P Dametto, B Li, ... Plos one 12 (2), e0170503, 2017 | 7 | 2017 |
| Oligodendrocytes Prune Axons Containing α-Synuclein Aggregates In Vivo: Lewy Neurites as Precursors of Glial Cytoplasmic Inclusions in Multiple System Atrophy? F De Nuccio, M Kashyrina, F Serinelli, F Laferrière, DD Lofrumento, ... Biomolecules 13 (2), 269, 2023 | 5 | 2023 |
