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Humberto Mestre, MD, PhD
Humberto Mestre, MD, PhD
Verificeret mail på pennmedicine.upenn.edu
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Citeret af
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The glymphatic pathway in neurological disorders
MK Rasmussen, H Mestre, M Nedergaard
The Lancet Neurology 17 (11), 1016-1024, 2018
10192018
Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension
H Mestre, J Tithof, T Du, W Song, W Peng, AM Sweeney, G Olveda, ...
Nature communications 9 (1), 4878, 2018
6452018
Suppression of glymphatic fluid transport in a mouse model of Alzheimer's disease
W Peng, TM Achariyar, B Li, Y Liao, H Mestre, E Hitomi, S Regan, ...
Neurobiology of disease 93, 215-225, 2016
4692016
Perivascular spaces in the brain: anatomy, physiology and pathology
JM Wardlaw, H Benveniste, M Nedergaard, BV Zlokovic, H Mestre, H Lee, ...
Nature Reviews Neurology 16 (3), 137-153, 2020
4672020
Aquaporin-4-dependent glymphatic solute transport in the rodent brain
H Mestre, LM Hablitz, ALR Xavier, W Feng, W Zou, T Pu, H Monai, ...
Elife 7, e40070, 2018
4512018
The brain’s glymphatic system: current controversies
H Mestre, Y Mori, M Nedergaard
Trends in neurosciences 43 (7), 458-466, 2020
3852020
Cerebrospinal fluid influx drives acute ischemic tissue swelling
H Mestre, T Du, AM Sweeney, G Liu, AJ Samson, W Peng, KN Mortensen, ...
Science 367 (6483), eaax7171, 2020
3372020
Perivascular spaces, glymphatic dysfunction, and small vessel disease
H Mestre, S Kostrikov, RI Mehta, M Nedergaard
Clinical science 131 (17), 2257-2274, 2017
2922017
Glymphatic clearance controls state-dependent changes in brain lactate concentration
I Lundgaard, ML Lu, E Yang, W Peng, H Mestre, E Hitomi, R Deane, ...
Journal of Cerebral Blood Flow & Metabolism 37 (6), 2112-2124, 2017
2672017
Glymphatic system impairment in Alzheimer’s disease and idiopathic normal pressure hydrocephalus
BC Reeves, JK Karimy, AJ Kundishora, H Mestre, HM Cerci, C Matouk, ...
Trends in molecular medicine 26 (3), 285-295, 2020
2552020
Fluid transport in the brain
MK Rasmussen, H Mestre, M Nedergaard
Physiological reviews 102 (2), 1025-1151, 2022
2282022
Impaired glymphatic transport in spontaneously hypertensive rats
KN Mortensen, S Sanggaard, H Mestre, H Lee, S Kostrikov, ALR Xavier, ...
Journal of Neuroscience 39 (32), 6365-6377, 2019
1582019
Transcranial optical imaging reveals a pathway for optimizing the delivery of immunotherapeutics to the brain
BA Plog, H Mestre, GE Olveda, AM Sweeney, HM Kenney, A Cove, ...
JCI insight 3 (20), 2018
752018
Direct measurement of cerebrospinal fluid production in mice
G Liu, H Mestre, AM Sweeney, Q Sun, P Weikop, T Du, M Nedergaard
Cell reports 33 (12), 2020
722020
Hydraulic resistance of periarterial spaces in the brain
J Tithof, DH Kelley, H Mestre, M Nedergaard, JH Thomas
Fluids and Barriers of the CNS 16, 1-13, 2019
642019
Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection
A Raghunandan, A Ladron-de-Guevara, J Tithof, H Mestre, T Du, ...
Elife 10, e65958, 2021
552021
Immunization with A91 peptide or Copolymer‐1 reduces the production of nitric oxide and inducible nitric oxide synthase gene expression after spinal cord injury
E García, R Silva‐García, H Mestre, N Flores, S Martiñón, ...
Journal of Neuroscience Research 90 (3), 656-663, 2012
532012
Immunization with neural-derived antigens inhibits lipid peroxidation after spinal cord injury
A Ibarra, E García, N Flores, S Martiñón, R Reyes, MG Campos, M Maciel, ...
Neuroscience letters 476 (2), 62-65, 2010
522010
Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke
H Monai, X Wang, K Yahagi, N Lou, H Mestre, Q Xu, Y Abe, M Yasui, ...
Proceedings of the National Academy of Sciences 116 (22), 11010-11019, 2019
492019
Periarteriolar spaces modulate cerebrospinal fluid transport into brain and demonstrate altered morphology in aging and Alzheimer’s disease
H Mestre, N Verma, TD Greene, LJA Lin, A Ladron-de-Guevara, ...
Nature communications 13 (1), 3897, 2022
442022
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