| Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response P Jiang*, S Gu*, D Pan*, J Fu, A Sahu, X Hu, Z Li, N Traugh, X Bu, B Li, ... Nature medicine 24 (10), 1550-1558, 2018 | 3066 | 2018 |
| Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism N Levaot, O Voytyuk, I Dimitriou, F Sircoulomb, A Chandrakumar, ... Cell 147 (6), 1324-1339, 2011 | 198 | 2011 |
| Landscape of B cell immunity and related immune evasion in human cancers X Hu, J Zhang, J Wang, J Fu, T Li, X Zheng, B Wang, S Gu, P Jiang, J Fan, ... Nature genetics 51 (3), 560-567, 2019 | 130 | 2019 |
| Therapeutically increasing MHC-I expression potentiates immune checkpoint blockade SS Gu*, W Zhang*, X Wang*, P Jiang*, N Traugh, Z Li, C Meyer, B Stewig, ... Cancer Discovery 11 (6), 1524-1541, 2021 | 108 | 2021 |
| Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells G Chan, LS Cheung, W Yang, M Milyavsky, AD Sanders, S Gu, WX Hong, ... Blood, The Journal of the American Society of Hematology 117 (16), 4253-4261, 2011 | 102 | 2011 |
| Enhanced efficacy of simultaneous PD-1 and PD-L1 immune checkpoint blockade in high-grade serous ovarian cancer C Wan, MP Keany, H Dong, LF Al-Alem, UM Pandya, S Lazo, K Boehnke, ... Cancer research 81 (1), 158-173, 2021 | 96 | 2021 |
| In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target X Wang*, C Tokheim*, SS Gu*, B Wang*, Q Tang, Y Li, N Traugh, Z Zeng, ... Cell, 2021 | 87 | 2021 |
| MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets X Qiu, N Boufaied, T Hallal, A Feit, A de Polo, AM Luoma, W Alahmadi, ... Nature communications 13 (1), 2559, 2022 | 70 | 2022 |
| Genetically defined, syngeneic organoid platform for developing combination therapies for ovarian cancer S Zhang, S Iyer, H Ran, I Dolgalev, S Gu, W Wei, CJR Foster, CA Loomis, ... Cancer discovery 11 (2), 362-383, 2021 | 56 | 2021 |
| Erk1 and Erk2 are required for maintenance of hematopoietic stem cells and adult hematopoiesis G Chan, S Gu, BG Neel Blood, The Journal of the American Society of Hematology 121 (18), 3594-3598, 2013 | 56 | 2013 |
| Increased BRAF heterodimerization is the common pathogenic mechanism for noonan syndrome-associated RAF1 mutants X Wu, J Yin, J Simpson, KH Kim, S Gu, JH Hong, P Bayliss, PH Backx, ... Molecular and cellular biology, 2012 | 53 | 2012 |
| TISMO: syngeneic mouse tumor database to model tumor immunity and immunotherapy response Z Zeng, CJ Wong, L Yang, N Ouardaoui, D Li, W Zhang, S Gu, Y Zhang, ... Nucleic acids research 50 (D1), D1391-D1397, 2022 | 51 | 2022 |
| Immune receptor repertoires in pediatric and adult acute myeloid leukemia J Zhang, X Hu, J Wang, AD Sahu, D Cohen, L Song, Z Ouyang, J Fan, ... Genome medicine 11, 1-11, 2019 | 45 | 2019 |
| SHP2 is required for BCR-ABL1-induced hematologic neoplasia S Gu, A Sayad, G Chan, W Yang, Z Lu, C Virtanen, RA Van Etten, ... Leukemia 32 (1), 203-213, 2018 | 41 | 2018 |
| Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1 S Gu*, WW Chan*, G Mohi*, J Rosenbaum, A Sayad, Z Lu, C Virtanen, ... Blood, The Journal of the American Society of Hematology 127 (14), 1803-1813, 2016 | 30 | 2016 |
| Inhibition of MAN2A1 Enhances the Immune Response to Anti–PD-L1 in Human Tumors S Shi*, S Gu*, T Han, W Zhang, L Huang, Z Li, D Pan, J Fu, J Ge, M Brown, ... Clinical Cancer Research 26 (22), 5990-6002, 2020 | 29 | 2020 |
| Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles MA Hatlen, K Arora, V Vacic, EA Grabowska, W Liao, B Riley-Gillis, ... Journal of Experimental Medicine 213 (1), 25-34, 2016 | 29 | 2016 |
| High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia W Du, J He, W Zhou, S Shu, J Li, W Liu, Y Deng, C Lu, S Lin, Y Ma, Y He, ... Journal of translational medicine 17, 1-14, 2019 | 25 | 2019 |
| CoBRA: containerized bioinformatics workflow for reproducible ChIP/ATAC-seq analysis X Qiu, AS Feit, A Feiglin, Y Xie, N Kesten, L Taing, J Perkins, S Gu, Y Li, ... Genomics, Proteomics and Bioinformatics 19 (4), 652-661, 2021 | 22 | 2021 |
| IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia BJ Aubrey, JA Cutler, W Bourgeois, KA Donovan, S Gu, C Hatton, ... Nature cancer 3 (5), 595-613, 2022 | 19 | 2022 |
