50 years of oral lipid-based formulations: provenance, progress and future perspectives OM Feeney, MF Crum, CL McEvoy, NL Trevaskis, HD Williams, ... Advanced drug delivery reviews 101, 167-194, 2016 | 391 | 2016 |
Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs P Matsson, JM Pedersen, U Norinder, CAS Bergström, P Artursson Pharmaceutical research 26, 1816-1831, 2009 | 360 | 2009 |
Absorption classification of oral drugs based on molecular surface properties CAS Bergström, M Strafford, L Lazorova, A Avdeef, K Luthman, ... Journal of medicinal chemistry 46 (4), 558-570, 2003 | 358 | 2003 |
Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems BJ Boyd, CAS Bergström, Z Vinarov, M Kuentz, J Brouwers, P Augustijns, ... European Journal of Pharmaceutical Sciences 137, 104967, 2019 | 319 | 2019 |
Prediction of ADMET properties U Norinder, CAS Bergström ChemMedChem: Chemistry Enabling Drug Discovery 1 (9), 920-937, 2006 | 308 | 2006 |
Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs CAS Bergström, R Holm, SA Jørgensen, SBE Andersson, P Artursson, ... European Journal of Pharmaceutical Sciences 57, 173-199, 2014 | 287 | 2014 |
Accuracy of calculated pH-dependent aqueous drug solubility CAS Bergström, K Luthman, P Artursson European journal of pharmaceutical sciences 22 (5), 387-398, 2004 | 242 | 2004 |
Experimental and computational screening models for prediction of aqueous drug solubility CAS Bergström, U Norinder, K Luthman, P Artursson Pharmaceutical research 19, 182-188, 2002 | 233 | 2002 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1 G Ahlin, J Karlsson, JM Pedersen, L Gustavsson, R Larsson, P Matsson, ... Journal of medicinal chemistry 51 (19), 5932-5942, 2008 | 222 | 2008 |
Computational prediction of drug solubility in water-based systems: Qualitative and quantitative approaches used in the current drug discovery and development setting CAS Bergström, P Larsson International journal of pharmaceutics 540 (1-2), 185-193, 2018 | 215 | 2018 |
Poorly soluble marketed drugs display solvation limited solubility CAS Bergström, CM Wassvik, K Johansson, I Hubatsch Journal of medicinal chemistry 50 (23), 5858-5862, 2007 | 207 | 2007 |
Dissolution rate and apparent solubility of poorly soluble drugs in biorelevant dissolution media JH Fagerberg, O Tsinman, N Sun, K Tsinman, A Avdeef, CAS Bergstrom Molecular pharmaceutics 7 (5), 1419-1430, 2010 | 203 | 2010 |
Computational prediction of formulation strategies for beyond-rule-of-5 compounds CAS Bergström, WN Charman, CJH Porter Advanced drug delivery reviews 101, 6-21, 2016 | 178 | 2016 |
Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11) JM Pedersen, P Matsson, CAS Bergström, J Hoogstraate, A Norén, ... toxicological sciences 136 (2), 328-343, 2013 | 174 | 2013 |
The biopharmaceutics classification system (BCS) and the biopharmaceutics drug disposition classification system (BDDCS): beyond guidelines A Charalabidis, M Sfouni, C Bergström, P Macheras International journal of pharmaceutics 566, 264-281, 2019 | 169 | 2019 |
Contribution of solid-state properties to the aqueous solubility of drugs CM Wassvik, AG Holmén, CAS Bergström, I Zamora, P Artursson European journal of pharmaceutical sciences 29 (3-4), 294-305, 2006 | 163 | 2006 |
Exploring the role of different drug transport routes in permeability screening P Matsson, CAS Bergström, N Nagahara, S Tavelin, U Norinder, ... Journal of medicinal chemistry 48 (2), 604-613, 2005 | 160 | 2005 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2) JM Pedersen, P Matsson, CAS Bergström, U Norinder, J Hoogstraate, ... Journal of medicinal chemistry 51 (11), 3275-3287, 2008 | 150 | 2008 |
A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2) P Matsson, G Englund, G Ahlin, CAS Bergström, U Norinder, P Artursson Journal of Pharmacology and Experimental Therapeutics 323 (1), 19-30, 2007 | 150 | 2007 |
Physical stability of drugs after storage above and below the glass transition temperature: Relationship to glass-forming ability A Alhalaweh, A Alzghoul, D Mahlin, CAS Bergström International journal of pharmaceutics 495 (1), 312-317, 2015 | 140 | 2015 |