Ian McDowell
Ian McDowell
Element Genomics, Inc. (UCB)
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Cited by
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Genetic effects on gene expression across human tissues
GTEx Consortium Lead analysts: Aguet Franšois 1 Brown Andrew A. 2 3 4 Castel ...
Nature 550 (7675), 204-213, 2017
Dynamic landscape and regulation of RNA editing in mammals
MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ...
Nature 550 (7675), 249-254, 2017
Direct GR binding sites potentiate clusters of TF binding across the human genome
CM Vockley, AM D’Ippolito, IC McDowell, WH Majoros, A Safi, L Song, ...
Cell 166 (5), 1269-1281. e19, 2016
Co-expression networks reveal the tissue-specific regulation of transcription and splicing
A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ...
Genome research 27 (11), 1843-1858, 2017
Clustering gene expression time series data using an infinite Gaussian process mixture model
IC McDowell, D Manandhar, CM Vockley, AK Schmid, TE Reddy, ...
PLoS computational biology 14 (1), e1005896, 2018
Transversions have larger regulatory effects than transitions
C Guo, IC McDowell, M Nodzenski, DM Scholtens, AS Allen, WL Lowe, ...
Bmc Genomics 18, 1-9, 2017
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding
IC McDowell, A Barrera, AM D'Ippolito, CM Vockley, LK Hong, ...
Genome research 28 (9), 1272-1284, 2018
Pre-established chromatin interactions mediate the genomic response to glucocorticoids
AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, ...
Cell systems 7 (2), 146-160. e7, 2018
Transcriptome of American oysters, Crassostrea virginica, in response to bacterial challenge: insights into potential mechanisms of disease resistance
IC McDowell, C Nikapitiya, D Aguiar, CE Lane, S Istrail, M Gomez-Chiarri
PLoS One 9 (8), e105097, 2014
Context specific and differential gene co-expression networks via Bayesian biclustering
C Gao, IC McDowell, S Zhao, CD Brown, BE Engelhardt
PLoS computational biology 12 (7), e1004791, 2016
Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis
F Yang, J Wang, BL Pierce, LS Chen, F Aguet, KG Ardlie, BB Cummings, ...
Genome research 27 (11), 1859-1871, 2017
Local genetic effects on gene expression across 44 human tissues
F Aguet, AA Brown, SE Castel, JR Davis, P Mohammadi, AV Segre, ...
BioRxiv, 074450, 2016
Multi-species protein similarity clustering reveals novel expanded immune gene families in the eastern oyster Crassostrea virginica
IC McDowell, TH Modak, CE Lane, M Gomez-Chiarri
Fish & shellfish immunology 53, 13-23, 2016
Human genome-wide measurement of drug-responsive regulatory activity
GD Johnson, A Barrera, IC McDowell, AM D’Ippolito, WH Majoros, ...
Nature communications 9 (1), 5317, 2018
Identification of potential general markers of disease resistance in American oysters, Crassostrea virginica through gene expression studies
C Nikapitiya, IC McDowell, L Villamil, P Mu˝oz, SB Sohn, ...
Fish & shellfish immunology 41 (1), 27-36, 2014
Causal network inference from gene transcriptional time-series response to glucocorticoids
J Lu, B Dumitrascu, IC McDowell, B Jo, A Barrera, LK Hong, SM Leichter, ...
PLoS computational biology 17 (1), e1008223, 2021
Genetic effects on gene expression across human tissues
DA Laboratory, NIHC Fund, BCS Site—NDRI, BCS Site—RPCI, ...
Nature 550 (7675), 204-213, 2017
A long-range flexible billboard model of gene activation
CM Vockley, IC McDowell, AM D'Ippolito, TE Reddy
Transcription 8 (4), 261-267, 2017
Distant regulatory effects of genetic variation in multiple human tissues
B Jo, Y He, BJ Strober, P Parsana, F Aguet, AA Brown, SE Castel, ...
BioRxiv, 074419, 2016
Many long intergenic non-coding RNAs distally regulate mRNA gene expression levels
IC McDowell, AA Pai, C Guo, CM Vockley, CD Brown, TE Reddy, ...
bioRxiv, 044719, 2016
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