Follow
Edward J Sayers
Edward J Sayers
Welsh Blood Service
Verified email at wales.nhs.uk
Title
Cited by
Cited by
Year
Cell entry of cell penetrating peptides: tales of tails wagging dogs
AT Jones, EJ Sayers
Journal of Controlled Release 161 (2), 582-591, 2012
2912012
Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines
SG Patel, EJ Sayers, L He, R Narayan, TL Williams, EM Mills, ...
Scientific Reports 9 (1), 6298, 2019
2072019
Receptor crosslinking: a general method to trigger internalization and lysosomal targeting of therapeutic receptor: ligand complexes
PR Moody, EJ Sayers, JP Magnusson, C Alexander, P Borri, P Watson, ...
Molecular Therapy 23 (12), 1888-1898, 2015
1082015
Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic
HD Roberts-Dalton, A Cocks, JM Falcon-Perez, EJ Sayers, JP Webber, ...
Nanoscale 9 (36), 13693-13706, 2017
1012017
Endocytic profiling of cancer cell models reveals critical factors influencing LNP-mediated mRNA delivery and protein expression
EJ Sayers, SE Peel, A Schantz, RM England, M Beano, SM Bates, ...
Molecular Therapy 27 (11), 1950-1962, 2019
712019
Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes
AR Nödling, EM Mills, X Li, D Cardella, EJ Sayers, SH Wu, AT Jones, ...
Chemical Communications 56 (34), 4672-4675, 2020
432020
Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides
EJ Sayers, K Cleal, NG Eissa, P Watson, AT Jones
Journal of Controlled Release 195, 55-62, 2014
402014
Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates
L He, EJ Sayers, P Watson, AT Jones
Scientific reports 8 (1), 7318, 2018
372018
Cell-penetrating antimicrobial peptides-prospectives for targeting intracellular infections
JS Bahnsen, H Franzyk, EJ Sayers, AT Jones, HM Nielsen
Pharmaceutical Research 32 (5), 1546-1556, 2015
312015
Co-operative Membrane Disruption Between Cell-penetrating Peptide and Cargo: Implications for the Therapeutic Use of the Bcl-2 Converter Peptide D-NuBCP-9-r8
CL Watkins, EJ Sayers, C Allender, D Barrow, C Fegan, P Brennan, ...
Molecular Therapy 19 (12), 2124-2132, 2011
302011
siRNA Inhibition of Endocytic Pathways to Characterize the Cellular Uptake Mechanisms of Folate-Functionalized Glycol Chitosan Nanogels
P Pereira, SS Pedrosa, JM Wymant, E Sayers, A Correia, M Vilanova, ...
Molecular pharmaceutics 12 (6), 1970-1979, 2015
252015
Highly luminescent metallacages featuring bispyridyl ligands functionalised with BODIPY for imaging in cancer cells
B Woods, D Döllerer, B Aikman, MN Wenzel, EJ Sayers, FE Kühn, ...
Journal of inorganic biochemistry 199, 110781, 2019
202019
Strategic Trastuzumab Mediated Crosslinking Driving Concomitant HER2 and HER3 Endocytosis and Degradation in Breast Cancer
JM Wymant, EJ Sayers, D Muir, AT Jones
Journal of Cancer 11 (11), 3288, 2020
162020
Switching of Macromolecular Ligand Display by Thermoresponsive Polymers Mediates Endocytosis of Multiconjugate Nanoparticles
EJ Sayers, JP Magnusson, PR Moody, F Mastrotto, C Conte, C Brazzale, ...
Bioconjugate chemistry 29 (4), 1030-1046, 2018
162018
Targeted delivery and endosomal cellular uptake of DARPin-siRNA bioconjugates: Influence of linker stability on gene silencing
C Lorenzer, S Streußnig, E Tot, AM Winkler, H Merten, F Brandl, ...
European Journal of Pharmaceutics and Biopharmaceutics 141, 37-50, 2019
152019
Four-wave-mixing microscopy reveals non-colocalisation between gold nanoparticles and fluorophore conjugates inside cells
N Giannakopoulou, JB Williams, PR Moody, EJ Sayers, JP Magnusson, ...
Nanoscale 12 (7), 4622-4635, 2020
122020
Highly-fluorescent BODIPY-functionalised metallacages as drug delivery systems: synthesis, characterisation and cellular accumulation studies
B Aikman, R Bonsignore, B Woods, D Doellerer, R Scotti, C Schmidt, ...
Dalton Transactions 51 (19), 7476-7490, 2022
102022
Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation
G Padalino, N El-Sakkary, LJ Liu, C Liu, DSG Harte, RE Barnes, E Sayers, ...
European Journal of Medicinal Chemistry 226, 113823, 2021
102021
EJP18 peptide derived from the juxtamembrane domain of epidermal growth factor receptor represents a novel membrane-active cell-penetrating peptide
NG Eissa, EJ Sayers, D Birch, SG Patel, YH Tsai, HM Nielsen, AT Jones
Biochemical Journal 477 (1), 45-60, 2020
72020
Influence of folate-targeted gold nanoparticles on subcellular localization and distribution into lysosomes
R Daniele, C Brazzale, B Arpac, F Tognetti, C Pesce, A Malfanti, E Sayers, ...
Pharmaceutics 15 (3), 864, 2023
52023
The system can't perform the operation now. Try again later.
Articles 1–20