| The genetics of ivermectin resistance in Caenorhabditis elegans JA Dent, MHM Smith, DK Vassilatis, L Avery Proceedings of the National Academy of Sciences 97 (6), 2674-2679, 2000 | 546 | 2000 |
| Primary sequence and immunological characterization of beta-subunit of high conductance Ca (2+)-activated K+ channel from smooth muscle. HG Knaus, K Folander, M Garcia-Calvo, ML Garcia, GJ Kaczorowski, ... Journal of Biological Chemistry 269 (25), 17274-17278, 1994 | 416 | 1994 |
| Two tarantula peptides inhibit activation of multiple sodium channels RE Middleton, VA Warren, RL Kraus, JC Hwang, CJ Liu, G Dai, ... Biochemistry 41 (50), 14734-14747, 2002 | 282 | 2002 |
| Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin NS Kane, B Hirschberg, S Qian, D Hunt, B Thomas, R Brochu, ... Proceedings of the National Academy of Sciences 97 (25), 13949-13954, 2000 | 239 | 2000 |
| Differential modification of the interaction of cardiac muscarinic cholinergic and beta-adrenergic receptors with a guanine nucleotide binding component (s). TK Harden, AG Scheer, MM Smith Molecular pharmacology 21 (3), 570-580, 1982 | 176 | 1982 |
| Blockers of the delayed-rectifier potassium current in pancreatic β-cells enhance glucose-dependent insulin secretion J Herrington, YP Zhou, RM Bugianesi, PM Dulski, Y Feng, VA Warren, ... Diabetes 55 (4), 1034-1042, 2006 | 170 | 2006 |
| Formation of the alpha-bungarotoxin binding site and assembly of the nicotinic acetylcholine receptor subunits occur in the endoplasmic reticulum. MM Smith, J Lindstrom, JP Merlie Journal of Biological Chemistry 262 (9), 4367-4376, 1987 | 144 | 1987 |
| Ivermectin and nodulisporic acid receptors in Drosophila melanogaster contain both γ-aminobutyric acid-gated Rdl and glutamate-gated GluClα chloride channel subunits SW Ludmerer, VA Warren, BS Williams, Y Zheng, DC Hunt, MB Ayer, ... Biochemistry 41 (20), 6548-6560, 2002 | 129 | 2002 |
| Assembly intermediates of the mouse muscle nicotinic acetylcholine receptor in stably transfected fibroblasts. P Blount, MM Smith, JP Merlie The Journal of cell biology 111 (6), 2601-2611, 1990 | 128 | 1990 |
| Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker C Abbadie, OB McManus, SY Sun, RM Bugianesi, G Dai, RJ Haedo, ... Journal of Pharmacology and Experimental Therapeutics 334 (2), 545-555, 2010 | 116 | 2010 |
| Muscarinic cholinergic receptors of two cell lines that regulate cyclic AMP metabolism by different molecular mechanisms. T Evans, MM Smith, LI Tanner, TK Harden Molecular pharmacology 26 (3), 395-404, 1984 | 115 | 1984 |
| Discovery of a novel class of benzazepinone Na v 1.7 blockers: potential treatments for neuropathic pain SB Hoyt, C London, D Gorin, MJ Wyvratt, MH Fisher, C Abbadie, JP Felix, ... Bioorganic & medicinal chemistry letters 17 (16), 4630-4634, 2007 | 111 | 2007 |
| Functional assay of voltage-gated sodium channels using membrane potential-sensitive dyes JP Felix, BS Williams, BT Priest, RM Brochu, IE Dick, VA Warren, L Yan, ... Assay and drug development technologies 2 (3), 260-268, 2004 | 100 | 2004 |
| A high-throughput assay for evaluating state dependence and subtype selectivity of Cav2 calcium channel inhibitors G Dai, RJ Haedo, VA Warren, KS Ratliff, RM Bugianesi, A Rush, ... Assay and drug development technologies 6 (2), 195-212, 2008 | 97 | 2008 |
| Nodulisporic acid opens insect glutamate-gated chloride channels: identification of a new high affinity modulator MHM Smith, VA Warren, BS Thomas, RM Brochu, EA Ertel, S Rohrer, ... Biochemistry 39 (18), 5543-5554, 2000 | 89 | 2000 |
| ProTx-I and ProTx-II: gating modifiers of voltage-gated sodium channels BT Priest, KM Blumenthal, JJ Smith, VA Warren, MHM Smith Toxicon 49 (2), 194-201, 2007 | 81 | 2007 |
| Synthesis and assembly of acetylcholine receptor, a multisubunit membrane glycoprotein JP Merlie, MM Smith Journal of Membrane Biology 91 (1), 1-10, 1986 | 80 | 1986 |
| Properties of three baculovirus-expressing genes that encode insect-selective toxins: μ-Aga-IV, As II, and Sh I GG Prikhod'ko, M Robson, JW Warmke, CJ Cohen, MHM Smith, P Wang, ... Biological Control 7 (2), 236-244, 1996 | 75 | 1996 |
| Characterization of the substituted N-triazole oxindole TROX-1, a small-molecule, state-dependent inhibitor of Cav2 calcium channels AM Swensen, J Herrington, RM Bugianesi, G Dai, RJ Haedo, KS Ratliff, ... Molecular pharmacology 81 (3), 488-497, 2012 | 72 | 2012 |
| Nodulisporic acids DF: structure, biological activities, and biogenetic relationships SB Singh, JG Ondeyka, H Jayasuriya, DL Zink, SN Ha, A Dahl-Roshak, ... Journal of natural products 67 (9), 1496-1506, 2004 | 70 | 2004 |
Richard BrochuCardiovascular and Metabolism, NovartisVerified email at novartis.com
