A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene J Luo, MJ Emanuele, D Li, CJ Creighton, MR Schlabach, TF Westbrook, ... Cell 137 (5), 835-848, 2009 | 1155 | 2009 |
A resource for large-scale RNA-interference-based screens in mammals PJ Paddison, JM Silva, DS Conklin, M Schlabach, M Li, S Aruleba, ... Nature 428 (6981), 427-431, 2004 | 924 | 2004 |
The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo KL Meerbrey, G Hu, JD Kessler, K Roarty, MZ Li, JE Fang, JI Herschkowitz, ... Proceedings of the National Academy of Sciences 108 (9), 3665-3670, 2011 | 699 | 2011 |
Energy-stress-mediated AMPK activation inhibits ferroptosis H Lee, F Zandkarimi, Y Zhang, JK Meena, J Kim, L Zhuang, S Tyagi, L Ma, ... Nature cell biology 22 (2), 225-234, 2020 | 656 | 2020 |
A genetic screen for candidate tumor suppressors identifies REST TF Westbrook, ES Martin, MR Schlabach, Y Leng, AC Liang, B Feng, ... Cell 121 (6), 837-848, 2005 | 593 | 2005 |
A pan-cancer proteogenomic atlas of PI3K/AKT/mTOR pathway alterations Y Zhang, PKS Ng, M Kucherlapati, F Chen, Y Liu, YH Tsang, ... Cancer cell 31 (6), 820-832. e3, 2017 | 516 | 2017 |
Integrated proteogenomic characterization of clear cell renal cell carcinoma DJ Clark, SM Dhanasekaran, F Petralia, J Pan, X Song, Y Hu, ... Cell 179 (4), 964-983. e31, 2019 | 491 | 2019 |
Cancer proliferation gene discovery through functional genomics MR Schlabach, J Luo, NL Solimini, G Hu, Q Xu, MZ Li, Z Zhao, ... Science 319 (5863), 620-624, 2008 | 462 | 2008 |
The spliceosome is a therapeutic vulnerability in MYC-driven cancer TYT Hsu, LM Simon, NJ Neill, R Marcotte, A Sayad, CS Bland, ... Nature 525 (7569), 384-388, 2015 | 458 | 2015 |
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis JD Kessler, KT Kahle, T Sun, KL Meerbrey, MR Schlabach, EM Schmitt, ... Science 335 (6066), 348-353, 2012 | 456 | 2012 |
Biology of human papillomaviruses HR McMurray, D Nguyen, TF Westbrook, DJ McAnce International journal of experimental pathology 82 (1), 15-33, 2001 | 418 | 2001 |
MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis A Terunuma, N Putluri, P Mishra, EA Mathé, TH Dorsey, M Yi, TA Wallace, ... The Journal of clinical investigation 124 (1), 398-412, 2014 | 416 | 2014 |
An animal model of MYC-driven medulloblastoma Y Pei, CE Moore, J Wang, AK Tewari, A Eroshkin, YJ Cho, H Witt, ... Cancer cell 21 (2), 155-167, 2012 | 377 | 2012 |
SCFβ-TRCP controls oncogenic transformation and neural differentiation through REST degradation TF Westbrook, G Hu, XL Ang, P Mulligan, NN Pavlova, A Liang, Y Leng, ... Nature 452 (7185), 370-374, 2008 | 362 | 2008 |
The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells H Wang, C Yu, X Gao, T Welte, AM Muscarella, L Tian, H Zhao, Z Zhao, ... Cancer cell 27 (2), 193-210, 2015 | 350 | 2015 |
Proteogenomic characterization of endometrial carcinoma Y Dou, EA Kawaler, DC Zhou, MA Gritsenko, C Huang, L Blumenberg, ... Cell 180 (4), 729-748. e26, 2020 | 325 | 2020 |
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphatase T Sun, N Aceto, KL Meerbrey, JD Kessler, C Zhou, I Migliaccio, ... Cell 144 (5), 703-718, 2011 | 314 | 2011 |
Proteogenomic landscape of breast cancer tumorigenesis and targeted therapy K Krug, EJ Jaehnig, S Satpathy, L Blumenberg, A Karpova, M Anurag, ... Cell 183 (5), 1436-1456. e31, 2020 | 312 | 2020 |
Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms IS Kim, Y Gao, T Welte, H Wang, J Liu, M Janghorban, K Sheng, Y Niu, ... Nature cell biology 21 (9), 1113-1126, 2019 | 235 | 2019 |
Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma C Huang, L Chen, SR Savage, RV Eguez, Y Dou, Y Li, ... Cancer cell 39 (3), 361-379. e16, 2021 | 220 | 2021 |