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Roopesh Anand
Roopesh Anand
The Francis Crick Institute
Verified email at imcr.uzh.ch
Title
Cited by
Cited by
Year
Restoration of replication fork stability in BRCA1-and BRCA2-deficient cells by inactivation of SNF2-family fork remodelers
A Taglialatela, S Alvarez, G Leuzzi, V Sannino, L Ranjha, JW Huang, ...
Molecular cell 68 (2), 414-430. e8, 2017
3432017
Phosphorylated CtIP functions as a co-factor of the MRE11-RAD50-NBS1 endonuclease in DNA end resection
R Anand, L Ranjha, E Cannavo, P Cejka
Molecular cell 64 (5), 940-950, 2016
3212016
SAMHD1 promotes DNA end resection to facilitate DNA repair by homologous recombination
W Daddacha, AE Koyen, AJ Bastien, PSE Head, VR Dhere, GN Nabeta, ...
Cell reports 20 (8), 1921-1935, 2017
1692017
The Saccharomyces cerevisiae Mlh1-Mlh3 heterodimer is an endonuclease that preferentially binds to Holliday junctions
L Ranjha, R Anand, P Cejka
Journal of Biological Chemistry 289 (9), 5674-5686, 2014
1432014
Regulation of the MLH1–MLH3 endonuclease in meiosis
E Cannavo, A Sanchez, R Anand, L Ranjha, J Hugener, C Adam, ...
Nature 586 (7830), 618-622, 2020
962020
RECQL4 promotes DNA end resection in repair of DNA double-strand breaks
H Lu, RA Shamanna, G Keijzers, R Anand, LJ Rasmussen, P Cejka, ...
Cell reports 16 (1), 161-173, 2016
962016
NBS1 promotes the endonuclease activity of the MRE11‐RAD50 complex by sensing CtIP phosphorylation
R Anand, A Jasrotia, D Bundschuh, SM Howard, L Ranjha, M Stucki, ...
The EMBO journal 38 (7), e101005, 2019
772019
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
O Belan, C Barroso, A Kaczmarczyk, R Anand, S Federico, N O’Reilly, ...
Molecular cell 81 (5), 1058-1073. e7, 2021
612021
CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection
I Ceppi, SM Howard, K Kasaciunaite, C Pinto, R Anand, R Seidel, P Cejka
Proceedings of the National Academy of Sciences 117 (16), 8859-8869, 2020
592020
The Mre11-Nbs1 interface is essential for viability and tumor suppression
JH Kim, M Grosbart, R Anand, C Wyman, P Cejka, JHJ Petrini
Cell reports 18 (2), 496-507, 2017
572017
MRE11-RAD50-NBS1 complex is sufficient to promote transcription by RNA polymerase II at double-strand breaks by melting DNA ends
S Sharma, R Anand, X Zhang, S Francia, F Michelini, A Galbiati, ...
Cell reports 34 (1), 2021
542021
POLQ seals post-replicative ssDNA gaps to maintain genome stability in BRCA-deficient cancer cells
O Belan, M Sebald, M Adamowicz, R Anand, A Vancevska, J Neves, ...
Molecular cell 82 (24), 4664-4680. e9, 2022
362022
HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51
R Anand, E Buechelmaier, O Belan, M Newton, A Vancevska, ...
Nature 601 (7892), 268-273, 2022
352022
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage
JW Huang, A Acharya, A Taglialatela, TS Nambiar, R Cuella-Martin, ...
Nature communications 11 (1), 2948, 2020
342020
Methods to study DNA end resection I: recombinant protein purification
R Anand, C Pinto, P Cejka
Methods in enzymology 600, 25-66, 2018
282018
Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2
S Halder, A Sanchez, L Ranjha, G Reginato, I Ceppi, A Acharya, R Anand, ...
Molecular Cell 82 (19), 3553-3565. e5, 2022
222022
Competing interaction partners modulate the activity of Sgs1 helicase during DNA end resection
K Kasaciunaite, F Fettes, M Levikova, P Daldrop, R Anand, P Cejka, ...
The EMBO journal 38 (13), e101516, 2019
222019
Development of insulin resistance preceded major changes in iron homeostasis in mice fed a high-fat diet
J Varghese, JV James, R Anand, M Narayanasamy, G Rebekah, ...
The Journal of nutritional biochemistry 84, 108441, 2020
192020
Methods to study DNA end resection II: biochemical reconstitution assays
C Pinto, R Anand, P Cejka
Methods in enzymology 600, 67-106, 2018
162018
The internal region of CtIP negatively regulates DNA end resection
SM Howard, I Ceppi, R Anand, R Geiger, P Cejka
Nucleic acids research 48 (10), 5485-5498, 2020
142020
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