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Dong Gao
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Organoid cultures derived from patients with advanced prostate cancer
D Gao, I Vela, A Sboner, PJ Iaquinta, WR Karthaus, A Gopalan, ...
Cell 159 (1), 176-187, 2014
14552014
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ...
Nature 547 (7664), 453-457, 2017
13662017
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53-and RB1-deficient prostate cancer
P Mu, Z Zhang, M Benelli, WR Karthaus, E Hoover, CC Chen, ...
Science 355 (6320), 84-88, 2017
8852017
Identification of multipotent luminal progenitor cells in human prostate organoid cultures
WR Karthaus, PJ Iaquinta, J Drost, A Gracanin, R Van Boxtel, J Wongvipat, ...
Cell 159 (1), 163-175, 2014
7122014
Organoid culture systems for prostate epithelial and cancer tissue
J Drost, WR Karthaus, D Gao, E Driehuis, CL Sawyers, Y Chen, H Clevers
Nature protocols 11 (2), 347-358, 2016
5702016
N-Myc induces an EZH2-mediated transcriptional program driving neuroendocrine prostate cancer
E Dardenne, H Beltran, M Benelli, K Gayvert, A Berger, L Puca, J Cyrta, ...
Cancer cell 30 (4), 563-577, 2016
5032016
ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss
Y Chen, P Chi, S Rockowitz, PJ Iaquinta, T Shamu, S Shukla, D Gao, ...
Nature medicine 19 (8), 1023-1029, 2013
3172013
Patient derived organoids to model rare prostate cancer phenotypes
L Puca, R Bareja, D Prandi, R Shaw, M Benelli, WR Karthaus, J Hess, ...
Nature communications 9 (1), 2404, 2018
2962018
Alternative transcription initiation leads to expression of a novel ALK isoform in cancer
T Wiesner, W Lee, AC Obenauf, L Ran, R Murali, QF Zhang, EWP Wong, ...
Nature 526 (7573), 453-457, 2015
2372015
SPOP mutation drives prostate tumorigenesis in vivo through coordinate regulation of PI3K/mTOR and AR signaling
M Blattner, D Liu, BD Robinson, D Huang, A Poliakov, D Gao, S Nataraj, ...
Cancer cell 31 (3), 436-451, 2017
2012017
In vitro expansion of primary human hepatocytes with efficient liver repopulation capacity
K Zhang, L Zhang, W Liu, X Ma, J Cen, Z Sun, C Wang, S Feng, Z Zhang, ...
Cell stem cell 23 (6), 806-819. e4, 2018
1852018
An embryonic diapause-like adaptation with suppressed Myc activity enables tumor treatment persistence
E Dhimolea, R de Matos Simoes, D Kansara, A Al’Khafaji, J Bouyssou, ...
Cancer cell 39 (2), 240-256. e11, 2021
1642021
PTEN deficiency and AMPK activation promote nutrient scavenging and anabolism in prostate cancer cells
SM Kim, TT Nguyen, A Ravi, P Kubiniok, BT Finicle, V Jayashankar, ...
Cancer discovery 8 (7), 866-883, 2018
1622018
REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I
D Gao, YK Yang, RP Wang, X Zhou, FC Diao, MD Li, ZH Zhai, ZF Jiang, ...
PloS one 4 (6), e5760, 2009
1492009
Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3
M Zhang, Y Tian, RP Wang, D Gao, Y Zhang, FC Diao, DY Chen, ZH Zhai, ...
Cell research 18 (11), 1096-1104, 2008
1452008
Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth
L Ran, I Sirota, Z Cao, D Murphy, Y Chen, S Shukla, Y Xie, MC Kaufmann, ...
Cancer discovery 5 (3), 304-315, 2015
1282015
Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2
Y Gu, J Cao, X Zhang, H Gao, Y Wang, J Wang, J He, X Jiang, J Zhang, ...
Cell research 32 (1), 24-37, 2022
1272022
Arterial Sca1+ vascular stem cells generate de novo smooth muscle for artery repair and regeneration
J Tang, H Wang, X Huang, F Li, H Zhu, Y Li, L He, H Zhang, W Pu, K Liu, ...
Cell stem cell 26 (1), 81-96. e4, 2020
1172020
Organoid development in cancer genome discovery
D Gao, Y Chen
Current opinion in genetics & development 30, 42-48, 2015
942015
Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips
W Guo, L Li, J He, Z Liu, M Han, F Li, X Xia, X Zhang, Y Zhu, YU Wei, Y Li, ...
Nature genetics 52 (9), 908-918, 2020
922020
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