| The role of interleukin-6 signaling in nervous tissue M Rothaug, C Becker-Pauly, S Rose-John Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (6), 1218-1227, 2016 | 450 | 2016 |
| Proteomic identification of protease cleavage sites characterizes prime and non-prime specificity of cysteine cathepsins B, L, and S ML Biniossek, DK Nägler, C Becker-Pauly, O Schilling Journal of proteome research 10 (12), 5363-5373, 2011 | 211 | 2011 |
| Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors MN Kruse, C Becker, D Lottaz, D Köhler, I Yiallouros, HW Krell, EE Sterchi, ... Biochemical Journal 378 (2), 383-389, 2004 | 202 | 2004 |
| Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus A Schütte, A Ermund, C Becker-Pauly, MEV Johansson, ... Proceedings of the National Academy of Sciences 111 (34), 12396-12401, 2014 | 187 | 2014 |
| The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis C Broder, C Becker-Pauly Biochemical Journal 450 (2), 253-264, 2013 | 156 | 2013 |
| The metalloprotease meprin β generates amino terminal-truncated amyloid β peptide species J Bien, T Jefferson, M Čaušević, T Jumpertz, L Munter, G Multhaup, ... Journal of Biological Chemistry 287 (40), 33304-33313, 2012 | 156 | 2012 |
| Metalloproteases meprin α and meprin β are C-and N-procollagen proteinases important for collagen assembly and tensile strength C Broder, P Arnold, S Vadon-Le Goff, MA Konerding, K Bahr, S Müller, ... Proceedings of the National Academy of Sciences 110 (35), 14219-14224, 2013 | 145 | 2013 |
| Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates C Becker-Pauly, O Barré, O Schilling, U auf dem Keller, A Ohler, C Broder, ... Molecular & Cellular Proteomics 10 (9), 2011 | 138 | 2011 |
| The α and β subunits of the metalloprotease meprin are expressed in separate layers of human epidermis, revealing different functions in keratinocyte proliferation and … C Becker-Pauly, M Höwel, T Walker, A Vlad, K Aufenvenne, V Oji, ... Journal of Investigative Dermatology 127 (5), 1115-1125, 2007 | 130 | 2007 |
| Differences in the activation mechanism between the α and β subunits of human meprin C Becker, MN Kruse, KA Slotty, D Köhler, JR Harris, S Rösmann, ... Walter de Gruyter 384 (5), 825-831, 2003 | 122 | 2003 |
| Proteolytic origin of the soluble human IL-6R in vivo and a decisive role of N-glycosylation S Riethmueller, P Somasundaram, JC Ehlers, CW Hung, CM Flynn, ... PLoS biology 15 (1), e2000080, 2017 | 121 | 2017 |
| Metalloprotease meprin β generates nontoxic N-terminal amyloid precursor protein fragments in vivo T Jefferson, M Čaušević, U auf dem Keller, O Schilling, S Isbert, R Geyer, ... Journal of Biological Chemistry 286 (31), 27741-27750, 2011 | 119 | 2011 |
| LC–MS based cleavage site profiling of the proteases ADAM10 and ADAM17 using proteome-derived peptide libraries J Tucher, D Linke, T Koudelka, L Cassidy, C Tredup, R Wichert, C Pietrzik, ... Journal of proteome research 13 (4), 2205-2214, 2014 | 118 | 2014 |
| The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10 T Jefferson, U auf dem Keller, C Bellac, VV Metz, C Broder, J Hedrich, ... Cellular and Molecular Life Sciences, 1-25, 2013 | 117 | 2013 |
| Processing of Procollagen III by Meprins: New Players in Extracellular Matrix Assembly D Kronenberg, BC Bruns, C Moali, S Vadon-Le Goff, EE Sterchi, H Traupe, ... Journal of Investigative Dermatology 130 (12), 2727-2735, 2010 | 98 | 2010 |
| Analyzing the protease web in skin: meprin metalloproteases are activated specifically by KLK4, 5 and 8 vice versa leading to processing of proKLK7 thereby … A Ohler, M Debela, S Wagner, V Magdolen, C Becker-Pauly Walter de Gruyter 391 (4), 455-460, 2010 | 92 | 2010 |
| Fetuin-A and cystatin C are endogenous inhibitors of human meprin metalloproteases J Hedrich, D Lottaz, K Meyer, I Yiallouros, W Jahnen-Dechent, ... Biochemistry 49 (39), 8599-8607, 2010 | 90 | 2010 |
| Meprin α and meprin β: Procollagen proteinases in health and disease J Prox, P Arnold, C Becker-Pauly Matrix Biology 44, 7-13, 2015 | 87 | 2015 |
| Structural basis for the sheddase function of human meprin β metalloproteinase at the plasma membrane JL Arolas, C Broder, T Jefferson, T Guevara, EE Sterchi, W Bode, ... Proceedings of the National Academy of Sciences 109 (40), 16131-16136, 2012 | 87 | 2012 |
| Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site C Schönherr, J Bien, S Isbert, R Wichert, J Prox, H Altmeppen, S Kumar, ... Molecular neurodegeneration 11, 1-16, 2016 | 82 | 2016 |
Stefan Rose-JohnUniversity of KielVerified email at biochem.uni-kiel.de
