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Fazal Shirazi
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Synthesis and antimicrobial activity of β-lactam–bile acid conjugates linked via triazole
NS Vatmurge, BG Hazra, VS Pore, F Shirazi, PS Chavan, MV Deshpande
Bioorganic & medicinal chemistry letters 18 (6), 2043-2047, 2008
2292008
Synthesis and evaluation of antifungal properties of a series of the novel 2-amino-5-oxo-4-phenyl-5, 6, 7, 8-tetrahydroquinoline-3-carbonitrile and its analogues
AR Gholap, KS Toti, F Shirazi, R Kumari, MK Bhat, MV Deshpande, ...
Bioorganic & medicinal chemistry 15 (21), 6705-6715, 2007
1812007
Efficient synthesis of antifungal pyrimidines via palladium catalyzed Suzuki/Sonogashira cross-coupling reaction from Biginelli 3, 4-dihydropyrimidin-2 (1H)-ones
AR Gholap, KS Toti, F Shirazi, MV Deshpande, KV Srinivasan
Tetrahedron 64 (44), 10214-10223, 2008
1172008
Synthesis and biological evaluation of bile acid dimers linked with 1, 2, 3-triazole and bis-β-lactam
NS Vatmurge, BG Hazra, VS Pore, F Shirazi, MV Deshpande, S Kadreppa, ...
Organic & Biomolecular Chemistry 6 (20), 3823-3830, 2008
992008
Exploration of click reaction for the synthesis of modified nucleosides as chitin synthase inhibitors
PM Chaudhary, SR Chavan, F Shirazi, M Razdan, P Nimkar, ...
Bioorganic & medicinal chemistry 17 (6), 2433-2440, 2009
872009
Protein targeting chimeric molecules specific for bromodomain and extra-terminal motif family proteins are active against pre-clinical models of multiple myeloma
X Zhang, HC Lee, F Shirazi, V Baladandayuthapani, H Lin, I Kuiatse, ...
Leukemia, 2018
772018
Ubiquitin-activating enzyme inhibition induces an unfolded protein response and overcomes drug resistance in myeloma
J Zhuang, F Shirazi, RK Singh, I Kuiatse, H Wang, HC Lee, Z Berkova, ...
Blood, The Journal of the American Society of Hematology 133 (14), 1572-1584, 2019
662019
Activating KRAS, NRAS, and BRAF Mutants Enhance Proteasome Capacity and Reduce Endoplasmic Reticulum Stress in Multiple Myeloma
F Shirazi, RJ Jones, RK Singh, J Zou, I Kuiatse, Z Berkova, H Wang, ...
Proc Natl Acad Sci U S A, 1-11, 2020
522020
Biofilm Filtrates of Pseudomonas aeruginosa Strains Isolated from Cystic Fibrosis Patients Inhibit Preformed Aspergillus fumigatus Biofilms via Apoptosis
F Shirazi, JAG Ferreira, DA Stevens, KV Clemons, DP Kontoyiannis
PloS one 11 (3), e0150155, 2016
492016
Possible mechanism of antifungal phenazine‐1‐carboxamide from Pseudomonas sp. against dimorphic fungi Benjaminiella poitrasii and human pathogen Candida albicans
SG Tupe, RR Kulkarni, F Shirazi, DG Sant, SP Joshi, MV Deshpande
Journal of applied microbiology 118 (1), 39-48, 2015
472015
Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain
BB Shingate, BG Hazra, DB Salunke, VS Pore, F Shirazi, MV Deshpande
European journal of medicinal chemistry 46 (9), 3681-3689, 2011
442011
Statin concentrations below the minimum inhibitory concentration attenuate the virulence of Rhizopus oryzae
AP Bellanger, AM Tatara, F Shirazi, T Gebremariam, ND Albert, RE Lewis, ...
Journal of Infectious Diseases 1 (214(1)), 114-21, 2016
432016
The Calcineurin Pathway Inhibitor Tacrolimus Enhances the In Vitro Activity of Azoles against Mucorales via Apoptosis
F Shirazi, DP Kontoyiannis
Eukaryotic cell 12 (9), 1225-1234, 2013
412013
Iron starvation induces apoptosis in Rhizopus oryzae in vitro
F Shirazi, DP Kontoyiannis, AS Ibrahim
Virulence 6 (2), 121-126, 2015
402015
Mitochondrial respiratory pathways inhibition in Rhizopus oryzae potentiates activity of posaconazole and itraconazole via apoptosis
F Shirazi, DP Kontoyiannis
PLOS ONE 8 (5), e63393, 2013
392013
Diet Modification and Metformin Have a Beneficial Effect in a Fly Model of Obesity and Mucormycosis
F Shirazi, D Farmakiotis, Y Yang, N Albert, KA Do, DP Kontoyiannis
PLoS One 9 (9), e108635, 2014
382014
Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents
SN Bavikar, DB Salunke, BG Hazra, VS Pore, RH Dodd, J Thierry, ...
Bioorganic & medicinal chemistry letters 18 (20), 5512-5517, 2008
382008
Micafungin triggers caspase-dependent apoptosis in Candida albicans and Candida parapsilosis biofilms, including caspofungin non-susceptible isolates
F Shirazi, DP Kontoyiannis
Virulence 6 (4), 385-394, 2015
302015
An antimicrobial peptidomimetic induces Mucorales cell death through mitochondria-mediated apoptosis
EM Barbu, F Shirazi, DM McGrath, N Albert, RL Sidman, R Pasqualini, ...
PLoS One 8 (10), e76981, 2013
302013
Targeting phosphatidylinositol 3 kinase-β and-δ for Bruton tyrosine kinase resistance in diffuse large B-cell lymphoma
N Jain, S Singh, G Laliotis, A Hart, E Muhowski, K Kupcova, T Chrbolkova, ...
Blood Advances 4 (18), 4382-4392, 2020
242020
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