| A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance SE Ward, JM O’Sullivan, C Drakeford, S Aguila, CN Jondle, J Sharma, ... Blood, The Journal of the American Society of Hematology 131 (8), 911-916, 2018 | 72 | 2018 |
| A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria N O’regan, K Gegenbauer, JM O’Sullivan, S Maleki, TM Brophy, N Dalton, ... Blood, The Journal of the American Society of Hematology 127 (9), 1192-1201, 2016 | 56 | 2016 |
| RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin αIIbβ3 TM Brophy, M Raab, H Daxecker, KG Culligan, I Lehmann, AJ Chubb, ... Biochemical and biophysical research communications 369 (4), 1088-1093, 2008 | 52 | 2008 |
| Increased galactose expression and enhanced clearance in patients with low von Willebrand factor S Aguila, M Lavin, N Dalton, S Patmore, A Chion, GD Trahan, KL Jones, ... Blood, The Journal of the American Society of Hematology 133 (14), 1585-1596, 2019 | 45 | 2019 |
| N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance A Chion, JM O’Sullivan, C Drakeford, G Bergsson, N Dalton, S Aguila, ... Blood, The Journal of the American Society of Hematology 128 (15), 1959-1968, 2016 | 45 | 2016 |
| Galectin-1 and galectin-3 constitute novel-binding partners for Factor VIII JM O’Sullivan, PV Jenkins, O Rawley, K Gegenbauer, A Chion, M Lavin, ... Arteriosclerosis, Thrombosis, and Vascular Biology 36 (5), 855-863, 2016 | 43 | 2016 |
| Plasmin Cleaves Von Willebrand Factor at K1491-R1492 in the A1–A2 Linker Region in a Shear-and Glycan-Dependent Manner In Vitro TM Brophy, SE Ward, TR McGimsey, S Schneppenheim, C Drakeford, ... Arteriosclerosis, thrombosis, and vascular biology 37 (5), 845-855, 2017 | 42 | 2017 |
| N‐linked glycan truncation causes enhanced clearance of plasma‐derived von Willebrand factor JM O'sullivan, S Aguila, E McRae, SE Ward, O Rawley, PG Fallon, ... Journal of Thrombosis and Haemostasis 14 (12), 2446-2457, 2016 | 42 | 2016 |
| Redox properties of the tissue factor Cys186-Cys209 disulfide bond HPH Liang, TM Brophy, PJ Hogg Biochemical Journal 437 (3), 455-460, 2011 | 42 | 2011 |
| Lenalidomide as a novel treatment for refractory acquired von Willebrand syndrome associated with monoclonal gammopathy M Lavin, TM Brophy, O Rawley, JM O'Sullivan, PJ Hayden, PV Browne, ... Journal of Thrombosis and Haemostasis 14 (6), 1200-1205, 2016 | 35 | 2016 |
| von Willebrand factor arginine 1205 substitution results in accelerated macrophage‐dependent clearance in vivo O Rawley, JM O'sullivan, A Chion, S Keyes, M Lavin, N van Rooijen, ... Journal of Thrombosis and Haemostasis 13 (5), 821-826, 2015 | 35 | 2015 |
| Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor β1 (TGF-β1) activation TM Brophy, BS Coller, J Ahamed Journal of Biological Chemistry 288 (15), 10628-10639, 2013 | 31 | 2013 |
| Marked elevation in plasma osteoprotegerin constitutes an early and consistent feature of cerebral malaria N O’Regan, C Moxon, K Gegenbauer, JM O’Sullivan, A Chion, OP Smith, ... Thrombosis and haemostasis 115 (04), 773-780, 2016 | 16 | 2016 |
| Investigating the clearance of VWF A‐domains using site‐directed PEGylation and novel N‐linked glycosylation J Fazavana, TM Brophy, A Chion, N Cooke, V Terraube, J Cohen, ... Journal of Thrombosis and Haemostasis 18 (6), 1278-1290, 2020 | 12 | 2020 |
| Hemostatic and protein C pathway dysfunction in the pathogenesis of experimental cerebral malaria N O’Regan, K Gegenbauer, EM Gleeson, K Fukudome, JM O’Sullivan, ... Haematologica 107 (8), 1950, 2022 | 3 | 2022 |
| Identification Of Galectin-1 and Galectin-3 As Novel Binding Partners For Factor VIII J O'Sullivan, O Rawley, V Jenkins, A Chion, TM Brophy, JS O'Donnell Blood 122 (21), 28-28, 2013 | 1 | 2013 |
| Exposure of von Willebrand factor (VWF) to vortex shear significantly enhances its proteolysis by plasmin TM Brophy, JS O'Donnell JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13, 749-749, 2015 | | 2015 |
| N-Linked Glycans within the A1A2A3 Domains of VWF Play a Critical Role in Modulating Macrophage-Mediated Clearance A Chion, J O’Sullivan, G Bergsson, S Keyes, O Rawley, P Fallon, ... Blood 124 (21), 469, 2014 | | 2014 |
| Conformation and N-linked glycan determinants within the A1A2A3 domains play critical roles in modulating human von Willebrand factor interaction with macrophages CKA Chion, G Bergsson, J O'Sullivan, O Rawley, S Keyes, V Jenkins, ... JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11, 466-466, 2013 | | 2013 |
| Defining the molecular basis underlying the physiological interaction between Von Willebrand factor and galectins in normal plasma O Rawley, JM O'Sullivan, A Chion, N O'Regan, VP Jenkins, TM Brophy, ... JOURNAL OF THROMBOSIS AND HAEMOSTASIS 11, 816-817, 2013 | | 2013 |
Jamie Marie O'SullivanRoyal College of Surgeons in IrelandVerified email at rcsi.ie
