| An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia B Knoechel, JE Roderick, KE Williamson, J Zhu, JG Lohr, MJ Cotton, ... Nature genetics 46 (4), 364-370, 2014 | 383 | 2014 |
| NOTCH1–RBPJ complexes drive target gene expression through dynamic interactions with superenhancers H Wang, C Zang, L Taing, KL Arnett, YJ Wong, WS Pear, SC Blacklow, ... Proceedings of the National Academy of Sciences 111 (2), 705-710, 2014 | 256 | 2014 |
| Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells H Wang, J Zou, B Zhao, E Johannsen, T Ashworth, H Wong, WS Pear, ... Proceedings of the National Academy of Sciences 108 (36), 14908-14913, 2011 | 255 | 2011 |
| T-cell factor 1 is a gatekeeper for T-cell specification in response to Notch signaling K Germar, M Dose, T Konstantinou, J Zhang, H Wang, C Lobry, KL Arnett, ... Proceedings of the National Academy of Sciences 108 (50), 20060-20065, 2011 | 235 | 2011 |
| Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors M Aste-Amézaga, N Zhang, JE Lineberger, BA Arnold, TJ Toner, M Gu, ... PLoS One 5 (2), e9094, 2010 | 214 | 2010 |
| Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth B Zhao, J Zou, H Wang, E Johannsen, C Peng, J Quackenbush, JC Mar, ... Proceedings of the National Academy of Sciences 108 (36), 14902-14907, 2011 | 212 | 2011 |
| High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling H Medyouf, S Gusscott, H Wang, JC Tseng, C Wai, O Nemirovsky, ... The Journal of experimental medicine 208 (9), 1809-1822, 2011 | 191 | 2011 |
| MYC, a downstream target of BRD-NUT, is necessary and sufficient for the blockade of differentiation in NUT midline carcinoma AR Grayson, EM Walsh, MJ Cameron, J Godec, T Ashworth, JM Ambrose, ... Oncogene 33 (13), 1736-1742, 2014 | 185 | 2014 |
| Vitamin C Promotes Maturation of T-Cells J Manning, B Mitchell, DA Appadurai, A Shakya, LJ Pierce, H Wang, ... Antioxidants & redox signaling 19 (17), 2054-2067, 2013 | 180 | 2013 |
| Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. YOY Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis ... Proc Natl Acad Sci U S A. 111 (46), 111(46):E4946-E4953, 2014 | 174* | 2014 |
| Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma Cancer discovery, 2014 | 154 | 2014 |
| The role of Notch receptors in transcriptional regulation H Wang, C Zang, XS Liu, JC Aster Journal of cellular physiology 230 (5), 982-988, 2015 | 136 | 2015 |
| L-selectin defines a bone marrow analog to the thymic early T-lineage progenitor SS Perry, H Wang, LJ Pierce, AM Yang, S Tsai, GJ Spangrude Blood 103 (8), 2990-2996, 2004 | 118 | 2004 |
| Gauging NOTCH1 activation in cancer using immunohistochemistry MJ Kluk, T Ashworth, H Wang, B Knoechel, EF Mason, EA Morgan, ... PloS one 8 (6), e67306, 2013 | 106 | 2013 |
| NOTCH1 promotes T cell leukemia-initiating activity by RUNX-mediated regulation of PKC-[theta] and reactive oxygen species V Giambra, CR Jenkins, H Wang, SH Lam, OO Shevchuk, O Nemirovsky, ... Nature medicine 18 (11), 1693-1698, 2012 | 101 | 2012 |
| Notch dimerization is required for leukemogenesis and T-cell development H Liu, AWS Chi, KL Arnett, MY Chiang, L Xu, O Shestova, H Wang, YM Li, ... Genes & development 24 (21), 2395-2407, 2010 | 89 | 2010 |
| Distinct roles of IL-7 and stem cell factor in the OP9-DL1 T-cell differentiation culture system H Wang, LJ Pierce, GJ Spangrude Experimental hematology 34 (12), 1730-1740, 2006 | 84 | 2006 |
| Network analysis of gene essentiality in functional genomics experiments P Jiang, H Wang, W Li, C Zang, B Li, YJ Wong, C Meyer, JS Liu, JC Aster, ... Genome biology 16 (1), 1-10, 2015 | 63 | 2015 |
| Lymphoid potential of primitive bone marrow progenitors evaluated in vitro H Wang, LJ Pierce, GJ Spangrude Annals of the New York Academy of Sciences 1044 (1), 210-219, 2005 | 13 | 2005 |
| Aspects of early lymphoid commitment H Wang, GJ Spangrude Current opinion in hematology 10 (3), 203-207, 2003 | 12 | 2003 |
