Dawn F. Ionescu, M.D.
Dawn F. Ionescu, M.D.
Senior Director, Neuroscience Experimental Medicine, Janssen Pharmaceuticals
Verified email at
Cited by
Cited by
Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD)
M Fava, MP Freeman, M Flynn, H Judge, BB Hoeppner, C Cusin, ...
Molecular psychiatry 25 (7), 1592-1603, 2020
Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety
ED Ballard, DF Ionescu, JLV Voort, MJ Niciu, EM Richards, ...
Journal of psychiatric research 58, 161-166, 2014
Do the dissociative side effects of ketamine mediate its antidepressant effects?
DA Luckenbaugh, MJ Niciu, DF Ionescu, NM Nolan, EM Richards, ...
Journal of affective disorders 159, 56-61, 2014
Pharmacological approaches to the challenge of treatment-resistant depression
DF Ionescu, JF Rosenbaum, JE Alpert
Dialogues in clinical neuroscience 17 (2), 111-126, 2015
Esketamine nasal spray for rapid reduction of major depressive disorder symptoms in patients who have active suicidal ideation with intent: double-blind, randomized study …
DJ Fu, DF Ionescu, X Li, R Lane, P Lim, G Sanacora, D Hough, H Manji, ...
The Journal of clinical psychiatry 81 (3), 6605, 2020
Glutamate and its receptors in the pathophysiology and treatment of major depressive disorder
MJ Niciu, DF Ionescu, EM Richards, CA Zarate
Journal of neural transmission 121, 907-924, 2014
Esketamine nasal spray for rapid reduction of depressive symptoms in patients with major depressive disorder who have active suicide ideation with intent: results of a phase 3 …
DF Ionescu, DJ Fu, X Qiu, R Lane, P Lim, S Kasper, D Hough, ...
International Journal of Neuropsychopharmacology 24 (1), 22-31, 2021
Clinical predictors of ketamine response in treatment-resistant major depression
MJ Niciu, DALDF Ionescu, S Guevara, R Machado-Vieira, EM Richards, ...
The Journal of clinical psychiatry 75 (5), 2921, 2014
Repeat-dose ketamine augmentation for treatment-resistant depression with chronic suicidal ideation: a randomized, double blind, placebo controlled trial
DF Ionescu, KH Bentley, M Eikermann, N Taylor, O Akeju, MB Swee, ...
Journal of affective disorders 243, 516-524, 2019
Neurobiology of anxious depression: a review
DF Ionescu, MJ Niciu, DC Mathews, EM Richards, CA Zarate Jr
Depression and anxiety 30 (4), 374-385, 2013
Objective assessment of depressive symptoms with machine learning and wearable sensors data
A Ghandeharioun, S Fedor, L Sangermano, D Ionescu, J Alpert, C Dale, ...
2017 seventh international conference on affective computing and intelligent …, 2017
Classics in chemical neuroscience: ketamine
MW Tyler, HB Yourish, DF Ionescu, SJ Haggarty
ACS chemical neuroscience 8 (6), 1122-1134, 2017
Towards new mechanisms: an update on therapeutics for treatment-resistant major depressive disorder
GI Papakostas, DF Ionescu
Molecular psychiatry 20 (10), 1142-1150, 2015
Near‐infrared transcranial radiation for major depressive disorder: proof of concept study
P Cassano, C Cusin, D Mischoulon, MR Hamblin, L De Taboada, A Pisoni, ...
Psychiatry journal 2015 (1), 352979, 2015
Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine
DF Ionescu, DA Luckenbaugh, MJ Niciu, EM Richards, EE Slonena, ...
The Journal of clinical psychiatry 75 (9), 5470, 2014
Rapid and sustained reductions in current suicidal ideation following repeated doses of intravenous ketamine: secondary analysis of an open-label study
DF Ionescu, MB Swee, KJ Pavone, N Taylor, O Akeju, L Baer, M Nyer, ...
The Journal of clinical psychiatry 77 (6), 10114, 2016
A single infusion of ketamine improves depression scores in patients with anxious bipolar depression
DF Ionescu, DA Luckenbaugh, MJ Niciu, EM Richards, CA Zarate Jr
Bipolar disorders 17 (4), 438-443, 2015
Defining anxious depression: a review of the literature
DF Ionescu, MJ Niciu, ID Henter, CA Zarate
CNS spectrums 18 (5), 252-260, 2013
Ketamine augmentation for outpatients with treatment-resistant depression: preliminary evidence for two-step intravenous dose escalation
C Cusin, DF Ionescu, KJ Pavone, O Akeju, P Cassano, N Taylor, ...
Australian & New Zealand Journal of Psychiatry 51 (1), 55-64, 2017
Ketamine-associated brain changes: a review of the neuroimaging literature
DF Ionescu, JM Felicione, A Gosai, C Cusin, P Shin, BG Shapero, ...
Harvard review of psychiatry 26 (6), 320-339, 2018
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