| A global reference for human genetic variation 1000 Genomes Project Consortium Nature 526 (7571), 68, 2015 | 4795 | 2015 |
| Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk A Rivera, SA Fisher, LG Fritsche, CN Keilhauer, P Lichtner, T Meitinger, ... Human molecular genetics 14 (21), 3227-3236, 2005 | 811 | 2005 |
| Seven new loci associated with age-related macular degeneration. LG Fritsche, W Chen, M Schu, BL Yaspan, Y Yu, G Thorleifsson, DJ Zack, ... Nature genetics 45 (4), 433-9, 439e1-2, 2013 | 597 | 2013 |
| A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants LG Fritsche, W Igl, JNC Bailey, F Grassmann, S Sengupta, ... Nature genetics 48 (2), 134-143, 2016 | 478 | 2016 |
| Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA LG Fritsche, T Loenhardt, A Janssen, SA Fisher, A Rivera, CN Keilhauer, ... Nature genetics 40 (7), 892-896, 2008 | 383 | 2008 |
| Systemic complement activation in age-related macular degeneration HPN Scholl, PC Issa, M Walier, S Janzer, B Pollok-Kopp, F Börncke, ... PloS one 3 (7), e2593, 2008 | 322 | 2008 |
| Age-related macular degeneration: genetics and biology coming together LG Fritsche, RN Fariss, D Stambolian, GR Abecasis, CA Curcio, ... Annual review of genomics and human genetics 15, 151-171, 2014 | 261 | 2014 |
| Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degeneration C Skerka, N Lauer, AAWA Weinberger, CN Keilhauer, J Sühnel, R Smith, ... Molecular immunology 44 (13), 3398-3406, 2007 | 198 | 2007 |
| An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD) LG Fritsche, N Lauer, A Hartmann, S Stippa, CN Keilhauer, M Oppermann, ... Human molecular genetics 19 (23), 4694-4704, 2010 | 172 | 2010 |
| Exome-wide association study of plasma lipids in> 300,000 individuals DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ... Nature genetics 49 (12), 1758, 2017 | 153 | 2017 |
| CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors JC Corbo, KA Lawrence, M Karlstetter, CA Myers, M Abdelaziz, W Dirkes, ... Genome research 20 (11), 1512-1525, 2010 | 145 | 2010 |
| Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology MA Ferreira, JM Vonk, H Baurecht, I Marenholz, C Tian, JD Hoffman, ... Nature genetics 49 (12), 1752, 2017 | 118 | 2017 |
| Evidence of association of APOE with age‐related macular degeneration‐a pooled analysis of 15 studies GJ McKay, CC Patterson, U Chakravarthy, S Dasari, CC Klaver, ... Human mutation 32 (12), 1407-1416, 2011 | 100 | 2011 |
| CFH, C3 and ARMS2 are significant risk loci for susceptibility but not for disease progression of geographic atrophy due to AMD HPN Scholl, M Fleckenstein, LG Fritsche, S Schmitz-Valckenberg, ... PLoS One 4 (10), e7418, 2009 | 94 | 2009 |
| No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38 EY Chew, ML Klein, TE Clemons, E Agrón, R Ratnapriya, AO Edwards, ... Ophthalmology 121 (11), 2173-2180, 2014 | 85 | 2014 |
| Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen, G Datta, ... Nature genetics 51 (2), 237, 2019 | 81 | 2019 |
| Modelling the Genetic Risk in Age-Related Macular Degeneration F Grassmann, LG Fritsche, CN Keilhauer, IM Heid, BHF Weber PloS one 7 (5), e37979, 2012 | 78 | 2012 |
| Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies W Zhou, JB Nielsen, LG Fritsche, R Dey, ME Gabrielsen, BN Wolford, ... Nature genetics 50 (9), 1335, 2018 | 77 | 2018 |
| Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype R Sofat, JP Casas, AR Webster, AC Bird, SS Mann, JRW Yates, AT Moore, ... International journal of epidemiology 41 (1), 250-262, 2012 | 72 | 2012 |
| Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people GJ McKay, G Silvestri, U Chakravarthy, S Dasari, LG Fritsche, BH Weber, ... American journal of epidemiology 173 (12), 1357-1364, 2011 | 72 | 2011 |
Goncalo AbecasisUniversity of Michigan School of Public HealthVerified email at umich.edu
