Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation G Ahlberg, L Refsgaard, PR Lundegaard, L Andreasen, MF Ranthe, ... Nature communications 9 (1), 4316, 2018 | 116 | 2018 |
Deletion of the Pluripotency-Associated Tex19.1 Gene Causes Activation of Endogenous Retroviruses and Defective Spermatogenesis in Mice R Öllinger, AJ Childs, HM Burgess, RM Speed, PR Lundegaard, ... PLoS genetics 4 (9), e1000199, 2008 | 89 | 2008 |
Fundamental role for the KCNE4 ancillary subunit in Kv7. 4 regulation of arterial tone TA Jepps, G Carr, PR Lundegaard, SP Olesen, IA Greenwood The Journal of physiology 593 (24), 5325-5340, 2015 | 80 | 2015 |
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs JG Diness, L Skibsbye, R Simó-Vicens, JL Santos, P Lundegaard, ... Circulation: Arrhythmia and Electrophysiology 10 (10), e005125, 2017 | 72 | 2017 |
Small molecule screening identifies targetable zebrafish pigmentation pathways S Colanesi, KL Taylor, ND Temperley, PR Lundegaard, D Liu, TE North, ... Pigment cell & melanoma research 25 (2), 131-143, 2012 | 70 | 2012 |
mc1r Pathway regulation of zebrafish melanosome dispersion J Richardson, PR Lundegaard, NL Reynolds, JR Dorin, DJ Porteous, ... Zebrafish 5 (4), 289-295, 2008 | 67 | 2008 |
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease JB Nielsen, O Rom, I Surakka, SE Graham, W Zhou, T Roychowdhury, ... Nature communications 11 (1), 6417, 2020 | 49 | 2020 |
High expression of markers of apoptosis in Langerhans cell histiocytosis BL Petersen, P Rengtved, MI Bank, H Carstensen Histopathology 42 (2), 186-193, 2003 | 44 | 2003 |
Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model MM Collins, G Ahlberg, CV Hansen, S Guenther, R Marín-Juez, AM Sokol, ... Proceedings of the National Academy of Sciences 116 (48), 24115-24121, 2019 | 43 | 2019 |
MEK inhibitors reverse cAMP-mediated anxiety in zebrafish PR Lundegaard, C Anastasaki, NJ Grant, RR Sillito, J Zich, Z Zeng, ... Chemistry & Biology 22 (10), 1335-1346, 2015 | 42 | 2015 |
Langerhans cell histiocytosis: An evaluation of histopathological parameters, demonstration of proliferation by Ki‐67 and mitotic bodies MI Bank, P Rengtved, H Carstensen, BL Petersen Apmis 111 (2), 300-308, 2003 | 41 | 2003 |
Quantitative proteome comparison of human hearts with those of model organisms N Linscheid, A Santos, PC Poulsen, RW Mills, K Calloe, U Leurs, JZ Ye, ... PLoS biology 19 (4), e3001144, 2021 | 36 | 2021 |
p53 expression in biopsies from children with Langerhans cell histiocytosis MI Bank, P Rengtved, H Carstensen, BL Petersen Journal of pediatric hematology/oncology 24 (9), 733-736, 2002 | 33 | 2002 |
Microtubule regulation of Kv7 channels orchestrates cAMP-mediated vasorelaxations in rat arterial smooth muscle J Lindman, MM Khammy, PR Lundegaard, C Aalkjær, TA Jepps Hypertension 71 (2), 336-345, 2018 | 30 | 2018 |
Combining etoposide and dexrazoxane synergizes with radiotherapy and improves survival in mice with central nervous system tumors KF Hofland, AV Thougaard, M Dejligbjerg, LH Jensen, PEG Kristjansen, ... Clinical cancer research 11 (18), 6722-6729, 2005 | 27 | 2005 |
Immunohistochemical detection of the apoptosis-related proteins FADD, FLICE, and FLIP in Langerhans cell histiocytosis MI Bank, C Gudbrand, P Rengtved, H Carstensen, B Fadeel, JI Henter, ... Journal of Pediatric Hematology/Oncology 27 (6), 301-306, 2005 | 21 | 2005 |
Early-onset atrial fibrillation patients show reduced left ventricular ejection fraction and increased atrial fibrosis L Andreasen, L Bertelsen, J Ghouse, PR Lundegaard, G Ahlberg, ... Scientific reports 10 (1), 10039, 2020 | 15 | 2020 |
Atrium‐specific ion channels in the zebrafish—A role of IKACh in atrial repolarization MA Skarsfeldt, SH Bomholtz, PR Lundegaard, A Lopez‐Izquierdo, ... Acta Physiologica 223 (3), e13049, 2018 | 15 | 2018 |
Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis J Ghouse, G Sveinbjörnsson, M Vujkovic, AS Seidelin, ... Nature Genetics, 1-11, 2024 | 13 | 2024 |
Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish AM Sokol, B Uszczynska-Ratajczak, MM Collins, M Bazala, U Topf, ... PLoS Genetics 14 (11), e1007743, 2018 | 12 | 2018 |