Diagnostic value of cerebrospinal fluid neurofilament light protein in neurology: a systematic review and meta-analysis C Bridel, WN Van Wieringen, H Zetterberg, BM Tijms, CE Teunissen, ... JAMA neurology 76 (9), 1035-1048, 2019 | 551 | 2019 |
Neurofilament light chain: a prognostic biomarker in amyotrophic lateral sclerosis CH Lu, C Macdonald-Wallis, E Gray, N Pearce, A Petzold, N Norgren, ... Neurology 84 (22), 2247-2257, 2015 | 504 | 2015 |
Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome J Kuhle, J Gaiottino, D Leppert, A Petzold, JP Bestwick, A Malaspina, ... Journal of Neurology, Neurosurgery & Psychiatry 86 (3), 273-279, 2015 | 189 | 2015 |
Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis CH Lu, K Allen, F Oei, E Leoni, J Kuhle, T Tree, P Fratta, N Sharma, ... Neurology: Neuroimmunology & Neuroinflammation 3 (4), e244, 2016 | 159 | 2016 |
The role of heat shock proteins in Amyotrophic Lateral Sclerosis: The therapeutic potential of Arimoclomol B Kalmar, CH Lu, L Greensmith Pharmacology & therapeutics 141 (1), 40-54, 2014 | 153 | 2014 |
CSF neurofilament light chain reflects corticospinal tract degeneration in ALS RAL Menke, E Gray, CH Lu, J Kuhle, K Talbot, A Malaspina, MR Turner Annals of clinical and translational neurology 2 (7), 748-755, 2015 | 143 | 2015 |
Targeting protein homeostasis in sporadic inclusion body myositis M Ahmed, PM Machado, A Miller, C Spicer, L Herbelin, J He, J Noel, ... Science translational medicine 8 (331), 331ra41-331ra41, 2016 | 126 | 2016 |
Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study CH Lu, A Petzold, J Topping, K Allen, C Macdonald-Wallis, J Clarke, ... Journal of Neurology, Neurosurgery & Psychiatry 86 (5), 565-573, 2015 | 111 | 2015 |
A method to solubilise protein aggregates for immunoassay quantification which overcomes the neurofilament “hook” effect CH Lu, B Kalmar, A Malaspina, L Greensmith, A Petzold Journal of neuroscience methods 195 (2), 143-150, 2011 | 74 | 2011 |
Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis I Magen, NS Yacovzada, E Yanowski, A Coenen-Stass, J Grosskreutz, ... Nature neuroscience 24 (11), 1534-1541, 2021 | 72 | 2021 |
Screening a UK amyotrophic lateral sclerosis cohort provides evidence of multiple origins of the C9orf72 expansion P Fratta, JM Polke, J Newcombe, S Mizielinska, T Lashley, M Poulter, ... Neurobiology of aging 36 (1), 546. e1-546. e7, 2015 | 68 | 2015 |
Plasma Neurofilament Heavy Chain Levels Correlate to Markers of Late Stage Disease Progression and Treatment Response in SOD1G93A Mice that Model ALS CH Lu, A Petzold, B Kalmar, J Dick, A Malaspina, L Greensmith PLoS One 7 (7), e40998, 2012 | 66 | 2012 |
Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy V Lombardi, G Querin, OJ Ziff, L Zampedri, I Martinelli, C Heller, M Foiani, ... Neurology 92 (11), e1205-e1211, 2019 | 56 | 2019 |
Combined tissue-fluid proteomics to unravel phenotypic variability in amyotrophic lateral sclerosis E Leoni, M Bremang, V Mitra, I Zubiri, S Jung, CH Lu, R Adiutori, ... Scientific Reports 9 (1), 4478, 2019 | 39 | 2019 |
Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis I Zubiri, V Lombardi, M Bremang, V Mitra, G Nardo, R Adiutori, CH Lu, ... Molecular Neurodegeneration 13 (1), 1-17, 2018 | 38 | 2018 |
Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis P Fratta, J Charnock, T Collins, A Devoy, R Howard, A Malaspina, R Orrell, ... Journal of Neurology, Neurosurgery & Psychiatry 85 (5), 506-508, 2014 | 26 | 2014 |
A motor neuron strategy to save time and energy in neurodegeneration: adaptive protein stoichiometry E Zucchi, CH Lu, Y Cho, R Chang, R Adiutori, I Zubiri, M Ceroni, ... Journal of Neurochemistry 146 (5), 631-641, 2018 | 24 | 2018 |
LB0002 safety and tolerability of arimoclomol in patients with sporadic inclusion body myositis: a randomised, double-blind, placebo-controlled, phase IIa proof-of-concept trial P Machado, A Miller, L Herbelin, J He, J Noel, Y Wang, AL McVey, ... Annals of the Rheumatic Diseases 72 (Suppl 3), A164-A164, 2013 | 23 | 2013 |
The potential of neurofilaments analysis using dry-blood and plasma spots V Lombardi, D Carassiti, G Giovannoni, CH Lu, R Adiutori, A Malaspina Scientific reports 10 (1), 97, 2020 | 22 | 2020 |
Protein aggregate formation permits millennium-old brain preservation A Petzold, CH Lu, M Groves, J Gobom, H Zetterberg, G Shaw, S O’Connor Journal of the Royal Society Interface 17 (162), 20190775, 2020 | 17 | 2020 |