| The efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 compared with rapamycin in renal cell carcinoma DC Cho, MB Cohen, DJ Panka, M Collins, M Ghebremichael, MB Atkins, ... Clinical Cancer Research 16 (14), 3628-3638, 2010 | 226 | 2010 |
| FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis B Gan, C Lim, G Chu, S Hua, Z Ding, M Collins, J Hu, S Jiang, ... Cancer cell 18 (5), 472-484, 2010 | 156 | 2010 |
| AZD5153: a novel bivalent BET bromodomain inhibitor highly active against hematologic malignancies GW Rhyasen, MM Hattersley, Y Yao, A Dulak, W Wang, P Petteruti, ... Molecular cancer therapeutics 15 (11), 2563-2574, 2016 | 145 | 2016 |
| Regulation and function of V-ATPases in physiology and disease MP Collins, M Forgac Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (12), 183341, 2020 | 91 | 2020 |
| Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression L Zhang, M Bhasin, R Schor-Bardach, X Wang, MP Collins, D Panka, ... PLoS One 6 (4), e19144, 2011 | 84 | 2011 |
| Synergistic induction of apoptosis by combination of BTK and dual mTORC1/2 inhibitors in diffuse large B cell lymphoma SA Ezell, M Mayo, T Bihani, S Tepsuporn, S Wang, M Passino, ... Oncotarget 5 (13), 4990, 2014 | 68 | 2014 |
| Renal cancer resistance to antiangiogenic therapy is delayed by restoration of angiostatic signaling RS Bhatt, X Wang, L Zhang, MP Collins, S Signoretti, DC Alsop, ... Molecular cancer therapeutics 9 (10), 2793-2802, 2010 | 68 | 2010 |
| Radiofrequency ablation combined with liposomal quercetin to increase tumour destruction by modulation of heat shock protein production in a small animal model W Yang, M Ahmed, B Tasawwar, T Levchenko, RR Sawant, M Collins, ... International Journal of Hyperthermia 27 (6), 527-538, 2011 | 61 | 2011 |
| Do liposomal apoptotic enhancers increase tumor coagulation and end-point survival in percutaneous radiofrequency ablation of tumors in a rat tumor model? W Yang, M Ahmed, M Elian, ESA Hady, TS Levchenko, RR Sawant, ... Radiology 257 (3), 685-696, 2010 | 57 | 2010 |
| Discovery of (+)-N-(3-Aminopropyl)-N-[1-(5-benzyl-3-methyl-4-oxo-[1,2]thiazolo[5,4-d]pyrimidin-6-yl)-2-methylpropyl]-4-methylbenzamide (AZD4877), a Kinesin … ME Theoclitou, B Aquila, MH Block, PJ Brassil, L Castriotta, E Code, ... Journal of medicinal chemistry 54 (19), 6734-6750, 2011 | 55 | 2011 |
| Regulation of V-ATPase assembly in nutrient sensing and function of V-ATPases in breast cancer metastasis MP Collins, M Forgac Frontiers in Physiology 9, 391760, 2018 | 54 | 2018 |
| GRK3 is essential for metastatic cells and promotes prostate tumor progression W Li, N Ai, S Wang, N Bhattacharya, V Vrbanac, M Collins, S Signoretti, ... Proceedings of the National Academy of Sciences 111 (4), 1521-1526, 2014 | 48 | 2014 |
| Orthotopic xenografts of RCC retain histological, immunophenotypic and genetic features of tumours in patients C Grisanzio, A Seeley, M Chang, M Collins, A Di Napoli, SC Cheng, ... The Journal of pathology 225 (2), 212-221, 2011 | 46 | 2011 |
| Comparisons of the efficacy of a Jak1/2 inhibitor (AZD1480) with a VEGF signaling inhibitor (cediranib) and sham treatments in mouse tumors using DCE-MRI, DW-MRI, and histology ME Loveless, D Lawson, M Collins, MVP Nadella, C Reimer, D Huszar, ... Neoplasia 14 (1), 54-64, 2012 | 41 | 2012 |
| STAT3 Antisense Oligonucleotide Remodels the Suppressive Tumor Microenvironment to Enhance Immune Activation in Combination with Anti–PD-L1 TA Proia, M Singh, R Woessner, L Carnevalli, G Bommakanti, L Magiera, ... Clinical Cancer Research 26 (23), 6335-6349, 2020 | 35 | 2020 |
| Isoform-specific gene disruptions reveal a role for the V-ATPase subunit a4 isoform in the invasiveness of 4T1-12B breast cancer cells CM McGuire, MP Collins, GH Sun-Wada, Y Wada, M Forgac Journal of Biological Chemistry 294 (29), 11248-11258, 2019 | 26 | 2019 |
| Effective combination therapies in preclinical endocrine resistant breast cancer models harboring ER mutations B Ladd, AM Mazzola, T Bihani, Z Lai, J Bradford, M Collins, E Barry, ... Oncotarget 7 (34), 54120, 2016 | 25 | 2016 |
| AKT Ser/Thr kinase increases V-ATPase–dependent lysosomal acidification in response to amino acid starvation in mammalian cells MP Collins, LA Stransky, M Forgac Journal of Biological Chemistry 295 (28), 9433-9444, 2020 | 18 | 2020 |
| Inhibition of platelet-derived growth factor receptor α by MEDI-575 reduces tumor growth and stromal fibroblast content in a model of non-small cell lung cancer N Laing, B McDermott, S Wen, D Yang, D Lawson, M Collins, C Reimer, ... Molecular pharmacology 83 (6), 1247-1256, 2013 | 16 | 2013 |
| Isoform a4 of the vacuolar ATPase a subunit promotes 4T1-12B breast cancer cell–dependent tumor growth and metastasis in vivo K Su, MP Collins, CM McGuire, MA Alshagawi, MK Alamoudi, Z Li, ... Journal of Biological Chemistry 298 (10), 2022 | 2 | 2022 |
