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Alexander Harms
Alexander Harms
ETH Zürich / Laboratory of Molecular Phage Biology
Verificeret mail på hest.ethz.ch - Startside
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Definitions and guidelines for research on antibiotic persistence
NQ Balaban, S Helaine, K Lewis, M Ackermann, B Aldridge, DI Andersson, ...
Nature Reviews Microbiology 17 (7), 441-448, 2019
9322019
Mechanisms of bacterial persistence during stress and antibiotic exposure
A Harms, E Maisonneuve, K Gerdes
Science 354 (6318), aaf4268, 2016
7922016
Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology
A Harms, DE Brodersen, N Mitarai, K Gerdes
Molecular Cell, 2018
5622018
Intruders below the radar: molecular pathogenesis of Bartonella spp.
A Harms, C Dehio
Clinical microbiology reviews 25 (1), 42-78, 2012
2732012
Prophages and growth dynamics confound experimental results with antibiotic-tolerant persister cells
A Harms, C Fino, MA Sørensen, S Semsey, K Gerdes
MBio 8 (6), 10.1128/mbio. 01964-17, 2017
2042017
Adenylylation control by intra-or intermolecular active-site obstruction in Fic proteins
P Engel, A Goepfert, FV Stanger, A Harms, A Schmidt, T Schirmer, ...
Nature 482 (7383), 107-110, 2012
1752012
Adenylylation of gyrase and topo IV by FicT toxins disrupts bacterial DNA topology
A Harms, FV Stanger, PD Scheu, IG de Jong, A Goepfert, T Glatter, ...
Cell reports 12 (9), 1497-1507, 2015
1032015
Systematic exploration of Escherichia coli phage–host interactions with the BASEL phage collection
E Maffei, A Shaidullina, M Burkolter, Y Heyer, F Estermann, V Druelle, ...
PLoS biology 19 (11), e3001424, 2021
982021
Birth and resuscitation of (p) ppGpp induced antibiotic tolerant persister cells
MS Svenningsen, A Veress, A Harms, N Mitarai, S Semsey
Scientific reports 9 (1), 6056, 2019
692019
A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella
A Harms, M Liesch, J Körner, M Québatte, P Engel, C Dehio
PLoS genetics 13 (10), e1007077, 2017
622017
Biological diversity and molecular plasticity of FIC domain proteins
A Harms, FV Stanger, C Dehio
Annual review of microbiology 70, 341-360, 2016
452016
Evolutionary Dynamics of Pathoadaptation Revealed by Three Independent Acquisitions of the VirB/D4 Type IV Secretion System in Bartonella
A Harms, FHID Segers, M Quebatte, C Mistl, P Manfredi, J Körner, ...
Genome biology and evolution 9 (3), 761-776, 2017
422017
Gene transfer agent promotes evolvability within the fittest subpopulation of a bacterial pathogen
M Québatte, M Christen, A Harms, J Körner, B Christen, C Dehio
Cell systems 4 (6), 611-621. e6, 2017
412017
An experimental strategy for the identification of AMPylation targets from complex protein samples
K Pieles, T Glatter, A Harms, A Schmidt, C Dehio
Proteomics 14 (9), 1048-1052, 2014
342014
Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacterial membrane
S Manioglu, SM Modaresi, N Ritzmann, J Thoma, SA Overall, A Harms, ...
Nature Communications 13 (1), 6195, 2022
332022
Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification
FV Stanger, BM Burmann, A Harms, H Aragão, A Mazur, T Sharpe, ...
Proceedings of the National Academy of Sciences 113 (5), E529-E537, 2016
332016
SLING: a tool to search for linked genes in bacterial datasets
G Horesh, A Harms, C Fino, L Parts, K Gerdes, E Heinz, NR Thomson
Nucleic Acids Research, 2018
262018
A Bartonella effector acts as signaling hub for intrinsic STAT3 activation to trigger anti-inflammatory responses
I Sorg, C Schmutz, YY Lu, K Fromm, LK Siewert, A Bögli, K Strack, ...
Cell host & microbe 27 (3), 476-485. e7, 2020
232020
Type II and type IV toxin–antitoxin systems show different evolutionary patterns in the global Klebsiella pneumoniae population
G Horesh, C Fino, A Harms, MJ Dorman, L Parts, K Gerdes, E Heinz, ...
Nucleic Acids Research, 2020
182020
Crystal Structure of the Escherichia coli Fic Toxin-Like Protein in Complex with Its Cognate Antitoxin
FV Stanger, A Harms, C Dehio, T Schirmer
PloS one 11 (9), e0163654, 2016
172016
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Artikler 1–20