| Trends in GPCR drug discovery: new agents, targets and indications AS Hauser, MM Attwood, M Rask-Andersen, HB Schiöth, DE Gloriam Nature reviews Drug discovery 16 (12), 829-842, 2017 | 2488 | 2017 |
| Pharmacogenomics of GPCR drug targets AS Hauser, S Chavali, I Masuho, LJ Jahn, KA Martemyanov, DE Gloriam, ... Cell 172 (1), 41-54. e19, 2018 | 651 | 2018 |
| GPCRdb in 2018: adding GPCR structure models and ligands G Pándy-Szekeres, C Munk, TM Tsonkov, S Mordalski, K Harpsøe, ... Nucleic acids research 46 (D1), D440-D446, 2018 | 563 | 2018 |
| GPCRDB: an information system for G protein-coupled receptors V Isberg, B Vroling, R van der Kant, K Li, G Vriend, D Gloriam Nucleic acids research 42 (D1), D422-D425, 2013 | 505* | 2013 |
| Selectivity determinants of GPCR–G-protein binding T Flock, AS Hauser, N Lund, DE Gloriam, S Balaji, MM Babu Nature 545 (7654), 317-322, 2017 | 399 | 2017 |
| GPCRdb: the G protein‐coupled receptor database–an introduction C Munk, V Isberg, S Mordalski, K Harpsøe, K Rataj, AS Hauser, P Kolb, ... British Journal of Pharmacology 173 (14), 2195-2207, 2016 | 240 | 2016 |
| Discovery of human signaling systems: pairing peptides to G protein-coupled receptors SR Foster, AS Hauser, L Vedel, RT Strachan, XP Huang, AC Gavin, ... Cell 179 (4), 895-908. e21, 2019 | 209 | 2019 |
| GPCR activation mechanisms across classes and macro/microscales AS Hauser, AJ Kooistra, C Munk, FM Heydenreich, DB Veprintsev, ... Nature structural & molecular biology 28 (11), 879-888, 2021 | 170 | 2021 |
| Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs C Avet, A Mancini, B Breton, C Le Gouill, AS Hauser, C Normand, ... Elife 11, e74101, 2022 | 151 | 2022 |
| Common coupling map advances GPCR-G protein selectivity AS Hauser, C Avet, C Normand, A Mancini, A Inoue, M Bouvier, ... Elife 11, e74107, 2022 | 99 | 2022 |
| LEADS-PEP: a benchmark data set for assessment of peptide docking performance AS Hauser, B Windshügel Journal of Chemical Information and Modeling 56 (1), 188-200, 2016 | 96 | 2016 |
| The G protein database, GproteinDb G Pándy-Szekeres, M Esguerra, AS Hauser, J Caroli, C Munk, S Pilger, ... Nucleic Acids Research 50 (D1), D518-D525, 2022 | 65 | 2022 |
| Integrating structural and mutagenesis data to elucidate GPCR ligand binding C Munk, K Harpsøe, AS Hauser, V Isberg, DE Gloriam Current opinion in pharmacology 30, 51-58, 2016 | 57 | 2016 |
| Glaucoma clinical research: Trends in treatment strategies and drug development L Storgaard, TL Tran, JC Freiberg, AS Hauser, M Kolko Frontiers in Medicine 8, 733080, 2021 | 56 | 2021 |
| The orphan G protein-coupled receptor GPR139 is activated by the peptides: adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and … AC Nøhr, MA Shehata, AS Hauser, V Isberg, J Mokrosinski, KB Andersen, ... Neurochemistry international 102, 105-113, 2017 | 43 | 2017 |
| Selectivity landscape of 100 therapeutically relevant GPCR profiled by an effector translocation-based BRET platform C Avet, A Mancini, B Breton, C Le Gouill, A Hauser, C Normand, ... | 42 | 2020 |
| Novel approaches leading towards peptide GPCR de‐orphanisation AS Hauser, DE Gloriam, H Bräuner‐Osborne, SR Foster British Journal of Pharmacology 177 (5), 961-968, 2020 | 37 | 2020 |
| Receptor selectivity between the G proteins Gα12 and Gα13 is defined by a single leucine-to-isoleucine variation AE Mackenzie, T Quon, LC Lin, AS Hauser, L Jenkins, A Inoue, AB Tobin, ... The FASEB Journal 33 (4), 5005, 2019 | 32 | 2019 |
| Ligand-directed bias of G protein signaling at the dopamine D2 receptor E Von Moo, K Harpsøe, AS Hauser, I Masuho, H Bräuner-Osborne, ... Cell chemical biology 29 (2), 226-238. e4, 2022 | 28 | 2022 |
| A new crystal structure fragment-based pharmacophore method for G protein-coupled receptors K Fidom, V Isberg, AS Hauser, S Mordalski, T Lehto, AJ Bojarski, ... Methods 71, 104-112, 2015 | 27 | 2015 |
David E. GloriamDepartment of Drug Design and Pharmacology, University of CopenhagenVerified email at sund.ku.dk
