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Simon Haas
Simon Haas
Berlin Institute of Health (BIH), Charité, BIMSB-MDC, German Cancer Research Center (DKFZ), HI-STEM
Verificeret mail på dkfz-heidelberg.de
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Transcriptional heterogeneity and lineage commitment in myeloid progenitors
F Paul, Y Arkin, A Giladi, DA Jaitin, E Kenigsberg, H Keren-Shaul, ...
Cell 163 (7), 1663-1677, 2015
11192015
Braveheart, a long noncoding RNA required for cardiovascular lineage commitment
CA Klattenhoff, JC Scheuermann, LE Surface, RK Bradley, PA Fields, ...
Cell 152 (3), 570-583, 2013
10162013
Human haematopoietic stem cell lineage commitment is a continuous process
L Velten, SF Haas, S Raffel, S Blaszkiewicz, S Islam, BP Hennig, C Hirche, ...
Nature cell biology 19 (4), 271-281, 2017
9192017
Combined single-cell and spatial transcriptomics reveal the molecular, cellular and spatial bone marrow niche organization
C Baccin, J Al-Sabah, L Velten, PM Helbling, F Grünschläger, ...
Nature cell biology 22 (1), 38-48, 2020
5742020
Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
N Cabezas-Wallscheid, D Klimmeck, J Hansson, DB Lipka, A Reyes, ...
Cell stem cell 15 (4), 507-522, 2014
5552014
Inflammation-induced emergency megakaryopoiesis driven by hematopoietic stem cell-like megakaryocyte progenitors
S Haas, J Hansson, D Klimmeck, D Loeffler, L Velten, H Uckelmann, ...
Cell stem cell 17 (4), 422-434, 2015
4242015
Causes and consequences of hematopoietic stem cell heterogeneity
S Haas, A Trumpp, MD Milsom
Cell stem cell 22 (5), 627-638, 2018
3182018
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ...
Nature genetics 49 (7), 1052-1060, 2017
2712017
Myc depletion induces a pluripotent dormant state mimicking diapause
R Scognamiglio, N Cabezas-Wallscheid, MC Thier, S Altamura, A Reyes, ...
Cell 164 (4), 668-680, 2016
2492016
Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
K Young, E Eudy, R Bell, MA Loberg, T Stearns, D Sharma, L Velten, ...
Cell Stem Cell 28 (8), 1473-1482. e7, 2021
962021
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states
S Triana, D Vonficht, L Jopp-Saile, S Raffel, R Lutz, D Leonce, M Antes, ...
Nature immunology 22 (12), 1577-1589, 2021
892021
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics
L Velten, BA Story, P Hernández-Malmierca, S Raffel, DR Leonce, ...
Nature communications 12 (1), 1366, 2021
872021
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging
R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ...
Cell Stem Cell 29 (8), 1273-1284. e8, 2022
832022
Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses
P Ketzer, SF Haas, S Engelhardt, JS Hartig, DM Nettelbeck
Nucleic acids research 40 (21), e167-e167, 2012
772012
Systemic virus infections differentially modulate cell cycle state and functionality of long-term hematopoietic stem cells in vivo
C Hirche, T Frenz, SF Haas, M Döring, K Borst, PK Tegtmeyer, I Brizic, ...
Cell Reports 19 (11), 2345-2356, 2017
692017
The traditional Chinese medical compound Rocaglamide protects nonmalignant primary cells from DNA damage-induced toxicity by inhibition of p53 expression
MS Becker, P Schmezer, R Breuer, SF Haas, MA Essers, PH Krammer, ...
Cell death & disease 5 (1), e1000-e1000, 2014
462014
IFNα-mediated remodeling of endothelial cells in the bone marrow niche
ÁM Prendergast, A Kuck, M van Essen, S Haas, S Blaszkiewicz, ...
Haematologica 102 (3), 445, 2017
442017
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3. 3-G34W-mutant giant cell tumor of bone
P Lutsik, A Baude, D Mancarella, S Öz, A Kühn, R Toth, J Hey, UH Toprak, ...
Nature communications 11 (1), 5414, 2020
402020
Identification of DNA methylation changes at cis-regulatory elements during early steps of HSC differentiation using tagmentation-based whole genome bisulfite …
DB Lipka, Q Wang, N Cabezas-Wallscheid, D Klimmeck, D Weichenhan, ...
Cell Cycle 13 (22), 3476-3487, 2014
402014
Antigen presentation safeguards the integrity of the hematopoietic stem cell pool
P Hernández-Malmierca, D Vonficht, A Schnell, HJ Uckelmann, ...
Cell Stem Cell 29 (5), 760-775. e10, 2022
362022
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