| bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation TJ McDonnell, N Deane, FM Platt, G Nunez, U Jaeger, JP McKearn, ... Cell 57 (1), 79-88, 1989 | 1605 | 1989 |
| Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease B Boland, A Kumar, S Lee, FM Platt, J Wegiel, WH Yu, RA Nixon Journal of Neuroscience 28 (27), 6926-6937, 2008 | 1226 | 2008 |
| Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis T Cox, R Lachmann, C Hollak, J Aerts, S Van Weely, M Hrebícek, F Platt, ... The Lancet 355 (9214), 1481-1485, 2000 | 946 | 2000 |
| Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium E Lloyd-Evans, AJ Morgan, X He, DA Smith, E Elliot-Smith, DJ Sillence, ... Nature medicine 14 (11), 1247-1255, 2008 | 909 | 2008 |
| Lysosomal storage disorders: The cellular impact of lysosomal dysfunction FM Platt, B Boland, AC van der Spoel Journal of Cell Biology 199 (5), 723-734, 2012 | 809 | 2012 |
| Lysosomal storage diseases FM Platt, A d’Azzo, BL Davidson, EF Neufeld, CJ Tifft Nature reviews Disease primers 4 (1), 27, 2018 | 765 | 2018 |
| N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis. FM Platt, GR Neises, RA Dwek, TD Butters Journal of Biological Chemistry 269 (11), 8362-8365, 1994 | 589 | 1994 |
| Targeting glycosylation as a therapeutic approach RA Dwek, TD Butters, FM Platt, N Zitzmann Nature reviews Drug discovery 1 (1), 65-75, 2002 | 541 | 2002 |
| Prevention of lysosomal storage in Tay-Sachs mice treated with N-butyldeoxynojirimycin FM Platt, GR Neises, G Reinkensmeier, MJ Townsend, VH Perry, ... Science 276 (5311), 428-431, 1997 | 458 | 1997 |
| Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase MA Simpson, H Cross, C Proukakis, DA Priestman, DCA Neville, ... Nature genetics 36 (11), 1225-1229, 2004 | 456 | 2004 |
| Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide G D’Angelo, E Polishchuk, GD Tullio, M Santoro, AD Campli, A Godi, ... Nature 449 (7158), 62-67, 2007 | 442 | 2007 |
| Common and uncommon pathogenic cascades in lysosomal storage diseases EB Vitner, FM Platt, AH Futerman Journal of Biological Chemistry 285 (27), 20423-20427, 2010 | 436 | 2010 |
| Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease AJ Morgan, FM Platt, E Lloyd-Evans, A Galione Biochemical Journal 439 (3), 349-378, 2011 | 434 | 2011 |
| Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans C De Santo, M Salio, SH Masri, LYH Lee, T Dong, AO Speak, S Porubsky, ... The Journal of clinical investigation 118 (12), 4036-4048, 2008 | 404 | 2008 |
| Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis M Jeyakumar, R Thomas, E Elliot‐Smith, DA Smith, AC Van Der Spoel, ... Brain 126 (4), 974-987, 2003 | 403 | 2003 |
| Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: implications for the development of broad spectrum … N Zitzmann, AS Mehta, S Carrouée, TD Butters, FM Platt, J McCauley, ... Proceedings of the National Academy of Sciences 96 (21), 11878-11882, 1999 | 384 | 1999 |
| Inhibition of glycosphingolipid biosynthesis: application to lysosomal storage disorders TD Butters, RA Dwek, FM Platt Chemical reviews 100 (12), 4683-4696, 2000 | 371 | 2000 |
| Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease JP Lee, M Jeyakumar, R Gonzalez, H Takahashi, PJ Lee, RC Baek, ... Nature medicine 13 (4), 439-447, 2007 | 358 | 2007 |
| Sphingolipid lysosomal storage disorders FM Platt Nature 510 (7503), 68-75, 2014 | 334 | 2014 |
| Delayed symptom onset and increased life expectancy in Sandhoff disease mice treated with N-butyldeoxynojirimycin M Jeyakumar, TD Butters, M Cortina-Borja, V Hunnam, RL Proia, ... Proceedings of the National Academy of Sciences 96 (11), 6388-6393, 1999 | 326 | 1999 |
Barry BolandUniversity College CorkVerificeret mail på ucc.ie
