RAD51-and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks Y Hashimoto, F Puddu, V Costanzo Nature structural & molecular biology 19 (1), 17-24, 2012 | 187 | 2012 |
Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint F Puddu, M Granata, L Di Nola, A Balestrini, G Piergiovanni, F Lazzaro, ... Molecular and cellular biology 28 (15), 4782-4793, 2008 | 147 | 2008 |
Checkpoint mechanisms at the intersection between DNA damage and repair F Lazzaro, M Giannattasio, F Puddu, M Granata, A Pellicioli, P Plevani, ... DNA repair 8 (9), 1055-1067, 2009 | 130 | 2009 |
Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation M Giannattasio, C Follonier, H Tourrière, F Puddu, F Lazzaro, P Pasero, ... Molecular cell 40 (1), 50-62, 2010 | 127 | 2010 |
Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle–regulated by CDK1 activity M Granata, F Lazzaro, D Novarina, D Panigada, F Puddu, CM Abreu, ... PLoS genetics 6 (8), e1001047, 2010 | 85 | 2010 |
Genome architecture and stability in the Saccharomyces cerevisiae knockout collection F Puddu, M Herzog, A Selivanova, S Wang, J Zhu, S Klein-Lavi, M Gordon, ... Nature 573 (7774), 416-420, 2019 | 78 | 2019 |
Sensing of replication stress and Mec1 activation act through two independent pathways involving the 9-1-1 complex and DNA polymerase ε F Puddu, G Piergiovanni, P Plevani, M Muzi-Falconi PLoS genetics 7 (3), e1002022, 2011 | 63 | 2011 |
Synthetic viability genomic screening defines Sae2 function in DNA repair F Puddu, T Oelschlaegel, I Guerini, NJ Geisler, H Niu, M Herzog, ... The EMBO journal 34 (11), 1509-1522, 2015 | 50 | 2015 |
Trajectory and uniqueness of mutational signatures in yeast mutators S Loeillet, M Herzog, F Puddu, P Legoix, S Baulande, SP Jackson, ... Proceedings of the National Academy of Sciences 117 (40), 24947-24956, 2020 | 30 | 2020 |
Phosphorylation of histone H4T80 triggers DNA damage checkpoint recovery G Millan-Zambrano, H Santos-Rosa, F Puddu, SC Robson, SP Jackson, ... Molecular cell 72 (4), 625-635. e4, 2018 | 29 | 2018 |
Chromatin determinants impart camptothecin sensitivity F Puddu, I Salguero, M Herzog, NJ Geisler, V Costanzo, SP Jackson EMBO reports 18 (6), 1000-1012, 2017 | 19 | 2017 |
Detection of functional protein domains by unbiased genome-wide forward genetic screening M Herzog, F Puddu, J Coates, N Geisler, JV Forment, SP Jackson Scientific reports 8 (1), 6161, 2018 | 14 | 2018 |
Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles M Herzog, E Alonso-Perez, I Salguero, J Warringer, DJ Adams, ... Nucleic acids research 49 (7), 3919-3931, 2021 | 13 | 2021 |
Large-scale exome sequence analysis identifies sex-and age-specific determinants of obesity LR Kaisinger, KA Kentistou, S Stankovic, EJ Gardner, FR Day, Y Zhao, ... Cell Genomics 3 (8), 2023 | 7 | 2023 |
More information from limited DNA: simultaneous measurement of genetics, 5hmC and 5mC in cell-free DNA TJ Charlesworth, F Puddu, R Crawford, A Johansson, E Lleshi, A Modat, ... Cancer Research 84 (6_Supplement), 2299-2299, 2024 | | 2024 |
Leveraging targeted epigenetic and genetic detection for cost-effective cancer classification R Crawford, B Krajacich, E Lleshi, A Negrea, L Andreasen, J Fullgrabe, ... Cancer Research 84 (6_Supplement), 6085-6085, 2024 | | 2024 |
Genetic and Epigenetic study of Formalin-damaged DNA R Crawford, J Scotcher, F Puddu, D Brudzewsky, J Hayward, A Tomoni, ... EUROPEAN JOURNAL OF HUMAN GENETICS 32, 620-620, 2024 | | 2024 |
Simultaneous measurement of genetics and epigenetics enables new biological insight N Harding, P Creed, D Currie, S Jamal, D Morley, F Puddu, C Lumby, ... EUROPEAN JOURNAL OF HUMAN GENETICS 32, 618-618, 2024 | | 2024 |
OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide H Sepulveda, X Li, X Yue, JC Angel, LJ Arteaga-Vazquez, C Brown, ... bioRxiv, 2024.01. 31.578097, 2024 | | 2024 |
Refining liquid biopsy: generating more information from cell free DNA F Puddu, CK Lumby, N Harding, DJ Morley, J Scotcher, R Crawford, ... Cancer Research 83 (7_Supplement), 6602-6602, 2023 | | 2023 |