| Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons JW Um, HB Nygaard, JK Heiss, MA Kostylev, M Stagi, A Vortmeyer, ... Nature neuroscience 15 (9), 1227-1235, 2012 | 754 | 2012 |
| Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein JW Um, AC Kaufman, M Kostylev, JK Heiss, M Stagi, H Takahashi, ... Neuron 79 (5), 887-902, 2013 | 644 | 2013 |
| Proteolytic cleavage of extracellular secreted α-synuclein via matrix metalloproteinases JY Sung, SM Park, CH Lee, JW Um, HJ Lee, J Kim, YJ Oh, ST Lee, ... Journal of Biological Chemistry 280 (26), 25216-25224, 2005 | 289 | 2005 |
| LAR-RPTPs: synaptic adhesion molecules that shape synapse development JW Um, J Ko Trends in cell biology 23 (10), 465-475, 2013 | 169 | 2013 |
| Amyloid-β induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease JW Um, SM Strittmatter Prion 7 (1), 37-41, 2013 | 149 | 2013 |
| Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer’s disease LT Haas, SV Salazar, MA Kostylev, JW Um, AC Kaufman, SM Strittmatter Brain 139 (2), 526-546, 2016 | 140 | 2016 |
| Functional modulation of parkin through physical interaction with SUMO‐1 JW Um, KC Chung Journal of neuroscience research 84 (7), 1543-1554, 2006 | 130 | 2006 |
| Parkin ubiquitinates and promotes the degradation of RanBP2 JW Um, H Rhim, J Kim, SR Paik, KC Chung Journal of biological chemistry 281 (6), 3595-3603, 2006 | 119 | 2006 |
| Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion JW Um, KH Kim, BS Park, Y Choi, D Kim, CY Kim, SJ Kim, M Kim, JS Ko, ... Nature Communications 5 (1), 5423, 2014 | 118 | 2014 |
| PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission JS Ko, G Pramanik, JW Um, JS Shim, D Lee, KH Kim, GY Chung, ... Proceedings of the National Academy of Sciences 112 (6), 1874-1879, 2015 | 113 | 2015 |
| Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures NH Tomioka, H Yasuda, H Miyamoto, M Hatayama, N Morimura, ... Nature communications 5 (1), 4501, 2014 | 106 | 2014 |
| Parkin cleaves intracellular α-synuclein inclusions via the activation of calpain SJ Kim, JY Sung, JW Um, N Hattori, Y Mizuno, K Tanaka, SR Paik, J Kim, ... Journal of Biological Chemistry 278 (43), 41890-41899, 2003 | 106 | 2003 |
| Parkin directly modulates 26S proteasome activity JW Um, E Im, HJ Lee, B Min, L Yoo, J Yoo, H Lübbert, C Stichel-Gunkel, ... Journal of Neuroscience 30 (35), 11805-11814, 2010 | 99 | 2010 |
| Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins JW Um, G Pramanik, JS Ko, MY Song, D Lee, H Kim, KS Park, TC Südhof, ... Cell reports 6 (6), 1096-1109, 2014 | 90 | 2014 |
| Molecular interaction between parkin and PINK1 in mammalian neuronal cells JW Um, C Stichel-Gunkel, H Lübbert, G Lee, KC Chung Molecular and Cellular Neuroscience 40 (4), 421-432, 2009 | 87 | 2009 |
| The balancing act of GABAergic synapse organizers J Ko, G Choii, JW Um Trends in molecular medicine 21 (4), 256-268, 2015 | 84 | 2015 |
| Synapse development organized by neuronal activity-regulated immediate-early genes S Kim, H Kim, JW Um Experimental & molecular medicine 50 (4), 1-7, 2018 | 82 | 2018 |
| SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development Y Choi, J Nam, DJ Whitcomb, YS Song, D Kim, S Jeon, JW Um, SG Lee, ... Scientific reports 6 (1), 26676, 2016 | 77 | 2016 |
| LRRTM3 regulates excitatory synapse development through alternative splicing and neurexin binding JW Um, TY Choi, H Kang, YS Cho, G Choii, P Uvarov, D Park, D Jeong, ... Cell reports 14 (4), 808-822, 2016 | 75 | 2016 |
| Neurotrophin-3 regulates synapse development by modulating TrkC-PTPσ synaptic adhesion and intracellular signaling pathways KA Han, D Woo, S Kim, G Choii, S Jeon, SY Won, HM Kim, W Do Heo, ... Journal of Neuroscience 36 (17), 4816-4831, 2016 | 73 | 2016 |
Jaewon KoDirector in the Center for Synapse Diversity and SpecificityVerified email at dgist.ac.kr
