|Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons|
JW Um, HB Nygaard, JK Heiss, MA Kostylev, M Stagi, A Vortmeyer, ...
Nature neuroscience 15 (9), 1227-1235, 2012
|Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein|
JW Um, AC Kaufman, M Kostylev, JK Heiss, M Stagi, H Takahashi, ...
Neuron 79 (5), 887-902, 2013
|Proteolytic cleavage of extracellular secreted α-synuclein via matrix metalloproteinases|
JY Sung, SM Park, CH Lee, JW Um, HJ Lee, J Kim, YJ Oh, ST Lee, ...
Journal of Biological Chemistry 280 (26), 25216-25224, 2005
|LAR-RPTPs: synaptic adhesion molecules that shape synapse development|
JW Um, J Ko
Trends in cell biology 23 (10), 465-475, 2013
|Amyloid-β induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease|
JW Um, SM Strittmatter
Prion 7 (1), 37-41, 2013
|Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer’s disease|
LT Haas, SV Salazar, MA Kostylev, JW Um, AC Kaufman, SM Strittmatter
Brain 139 (2), 526-546, 2016
|Functional modulation of parkin through physical interaction with SUMO‐1|
JW Um, KC Chung
Journal of neuroscience research 84 (7), 1543-1554, 2006
|Parkin ubiquitinates and promotes the degradation of RanBP2|
JW Um, H Rhim, J Kim, SR Paik, KC Chung
Journal of biological chemistry 281 (6), 3595-3603, 2006
|Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion|
JW Um, KH Kim, BS Park, Y Choi, D Kim, CY Kim, SJ Kim, M Kim, JS Ko, ...
Nature Communications 5 (1), 5423, 2014
|Parkin cleaves intracellular α-synuclein inclusions via the activation of calpain|
SJ Kim, JY Sung, JW Um, N Hattori, Y Mizuno, K Tanaka, SR Paik, J Kim, ...
Journal of Biological Chemistry 278 (43), 41890-41899, 2003
|PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission|
JS Ko, G Pramanik, JW Um, JS Shim, D Lee, KH Kim, GY Chung, ...
Proceedings of the National Academy of Sciences 112 (6), 1874-1879, 2015
|Parkin directly modulates 26S proteasome activity|
JW Um, E Im, HJ Lee, B Min, L Yoo, J Yoo, H Lübbert, C Stichel-Gunkel, ...
Journal of Neuroscience 30 (35), 11805-11814, 2010
|Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures|
NH Tomioka, H Yasuda, H Miyamoto, M Hatayama, N Morimura, ...
Nature communications 5 (1), 4501, 2014
|Molecular interaction between parkin and PINK1 in mammalian neuronal cells|
JW Um, C Stichel-Gunkel, H Lübbert, G Lee, KC Chung
Molecular and Cellular Neuroscience 40 (4), 421-432, 2009
|Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins|
JW Um, G Pramanik, JS Ko, MY Song, D Lee, H Kim, KS Park, TC Südhof, ...
Cell reports 6 (6), 1096-1109, 2014
|The balancing act of GABAergic synapse organizers|
J Ko, G Choii, JW Um
Trends in molecular medicine 21 (4), 256-268, 2015
|LRRTM3 regulates excitatory synapse development through alternative splicing and neurexin binding|
JW Um, TY Choi, H Kang, YS Cho, G Choii, P Uvarov, D Park, D Jeong, ...
Cell reports 14 (4), 808-822, 2016
|SALM5 trans-synaptically interacts with LAR-RPTPs in a splicing-dependent manner to regulate synapse development|
Y Choi, J Nam, DJ Whitcomb, YS Song, D Kim, S Jeon, JW Um, SG Lee, ...
Scientific reports 6 (1), 26676, 2016
|Neurotrophin-3 regulates synapse development by modulating TrkC-PTPσ synaptic adhesion and intracellular signaling pathways|
KA Han, D Woo, S Kim, G Choii, S Jeon, SY Won, HM Kim, W Do Heo, ...
Journal of Neuroscience 36 (17), 4816-4831, 2016
|Synapse development organized by neuronal activity-regulated immediate-early genes|
S Kim, H Kim, JW Um
Experimental & molecular medicine 50 (4), 1-7, 2018