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Vikram Khipple Mulligan
Vikram Khipple Mulligan
Systems Biology, Center for Computational Biology, Flatiron Institute
Verified email at flatironinstitute.org
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Cited by
Cited by
Year
The Rosetta all-atom energy function for macromolecular modeling and design
RF Alford, A Leaver-Fay, JR Jeliazkov, MJ O’Meara, FP DiMaio, H Park, ...
Journal of chemical theory and computation 13 (6), 3031-3048, 2017
12382017
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
5602020
Global analysis of protein folding using massively parallel design, synthesis, and testing
GJ Rocklin, TM Chidyausiku, I Goreshnik, A Ford, S Houliston, A Lemak, ...
Science 357 (6347), 168-175, 2017
4862017
Simultaneous optimization of biomolecular energy functions on features from small molecules and macromolecules
H Park, P Bradley, P Greisen Jr, Y Liu, VK Mulligan, DE Kim, D Baker, ...
Journal of chemical theory and computation 12 (12), 6201-6212, 2016
4092016
Accurate de novo design of hyperstable constrained peptides
G Bhardwaj, VK Mulligan, CD Bahl, JM Gilmore, PJ Harvey, O Cheneval, ...
Nature 538 (7625), 329-335, 2016
3842016
De novo design of bioactive protein switches
RA Langan, SE Boyken, AH Ng, JA Samson, G Dods, AM Westbrook, ...
Nature 572 (7768), 205-210, 2019
2492019
Programmable design of orthogonal protein heterodimers
Z Chen, SE Boyken, M Jia, F Busch, D Flores-Solis, MJ Bick, P Lu, ...
Nature 565 (7737), 106-111, 2019
1792019
Accurate computational design of multipass transmembrane proteins
P Lu, D Min, F DiMaio, KY Wei, MD Vahey, SE Boyken, Z Chen, JA Fallas, ...
Science 359 (6379), 1042-1046, 2018
1692018
Comprehensive computational design of ordered peptide macrocycles
P Hosseinzadeh, G Bhardwaj, VK Mulligan, MD Shortridge, TW Craven, ...
Science 358 (6369), 1461-1466, 2017
1642017
Prion disease susceptibility is affected by β-structure folding propensity and local side-chain interactions in PrP
MQ Khan, B Sweeting, VK Mulligan, PE Arslan, NR Cashman, EF Pai, ...
Proceedings of the National Academy of Sciences 107 (46), 19808-19813, 2010
1462010
Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy
JH Mills, SD Khare, JM Bolduc, F Forouhar, VK Mulligan, S Lew, ...
Journal of the American Chemical Society 135 (36), 13393-13399, 2013
1292013
Protein misfolding in the late‐onset neurodegenerative diseases: Common themes and the unique case of amyotrophic lateral sclerosis
VK Mulligan, A Chakrabartty
Proteins: Structure, Function, and Bioinformatics 81 (8), 1285-1303, 2013
1002013
Drosophila melanogaster Cad99C, the orthologue of human Usher cadherin PCDH15, regulates the length of microvilli
C D'Alterio, DDD Tran, MWYA Yeung, MSH Hwang, MA Li, CJ Arana, ...
The Journal of cell biology 171 (3), 549-558, 2005
812005
CCM3/PDCD10 Heterodimerizes with Germinal Center Kinase III (GCKIII) Proteins Using a Mechanism Analogous to CCM3 Homodimerization*♦
DF Ceccarelli, RC Laister, VK Mulligan, MJ Kean, M Goudreault, IC Scott, ...
Journal of Biological Chemistry 286 (28), 25056-25064, 2011
792011
Denaturational stress induces formation of zinc-deficient monomers of Cu, Zn superoxide dismutase: implications for pathogenesis in amyotrophic lateral sclerosis
VK Mulligan, A Kerman, S Ho, A Chakrabartty
Journal of molecular biology 383 (2), 424-436, 2008
672008
Early steps in oxidation-induced SOD1 misfolding: implications for non-amyloid protein aggregation in familial ALS
VK Mulligan, A Kerman, RC Laister, PR Sharda, PE Arslan, ...
Journal of molecular biology 421 (4-5), 631-652, 2012
652012
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
B Dang, H Wu, VK Mulligan, M Mravic, Y Wu, T Lemmin, A Ford, DA Silva, ...
Proceedings of the National Academy of Sciences 114 (41), 10852-10857, 2017
592017
ALS-causing SOD1 mutations promote production of copper-deficient misfolded species
P Ip, VK Mulligan, A Chakrabartty
Journal of molecular biology 409 (5), 839-852, 2011
572011
Accurate de novo design of membrane-traversing macrocycles
G Bhardwaj, J O’Connor, S Rettie, YH Huang, TA Ramelot, VK Mulligan, ...
Cell 185 (19), 3520-3532. e26, 2022
552022
Designing peptides on a quantum computer
VK Mulligan, H Melo, HI Merritt, S Slocum, BD Weitzner, AM Watkins, ...
BioRxiv, 752485, 2019
522019
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