Filip Van Petegem
Citeret af
Citeret af
Structure of a complex between a voltage-gated calcium channel β-subunit and an α-subunit domain
F Van Petegem, KA Clark, FC Chatelain, DL Minor
Nature 429 (6992), 671-675, 2004
Ryanodine receptors: structure and function
F Van Petegem
Journal of Biological Chemistry 287 (38), 31624-31632, 2012
Insights into voltage-gated calcium channel regulation from the structure of the CaV1. 2 IQ domain–Ca2+/calmodulin complex
F Van Petegem, FC Chatelain, DL Minor
Nature structural & molecular biology 12 (12), 1108-1115, 2005
The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule
CC Tung, PA Lobo, L Kimlicka, F Van Petegem
Nature 468 (7323), 585-588, 2010
The structure of a cold-adapted family 8 xylanase at 1.3 Å resolution: structural adaptations to cold and investigation of the active site
F Van Petegem, T Collins, MA Meuwis, C Gerday, G Feller, ...
Journal of Biological Chemistry 278 (9), 7531-7539, 2003
Ryanodine receptors: allosteric ion channel giants
F Van Petegem
Journal of molecular biology 427 (1), 31-53, 2015
Crystal structures of a psychrophilic metalloprotease reveal new insights into catalysis by cold‐adapted proteases
N Aghajari, F Van Petegem, V Villeret, JP Chessa, C Gerday, R Haser, ...
Proteins: Structure, Function, and Bioinformatics 50 (4), 636-647, 2003
Crystallographic basis for calcium regulation of sodium channels
MF Sarhan, CC Tung, F Van Petegem, CA Ahern
Proceedings of the National Academy of Sciences 109 (9), 3558-3563, 2012
Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations
PA Lobo, F Van Petegem
Structure 17 (11), 1505-1514, 2009
Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain
Z Yuchi, K Lau, F Van Petegem
Structure 20 (7), 1201-1211, 2012
Defining the stoichiometry of inositol 1, 4, 5-trisphosphate binding required to initiate Ca2+ release
KJ Alzayady, L Wang, R Chandrasekhar, LE Wagner, F Van Petegem, ...
Science signaling 9 (422), ra35-ra35, 2016
Structures of CaV2 Ca2+/CaM-IQ domain complexes reveal binding modes that underlie calcium-dependent inactivation and facilitation
EY Kim, CH Rumpf, Y Fujiwara, ES Cooley, F Van Petegem, DL Minor Jr
Structure 16 (10), 1455-1467, 2008
Crystallographic insights into sodium-channel modulation by the β4 subunit
J Gilchrist, S Das, F Van Petegem, F Bosmans
Proceedings of the National Academy of Sciences 110 (51), E5016-E5024, 2013
A DNA ligase from the psychrophile Pseudoalteromonas haloplanktis gives insights into the adaptation of proteins to low temperatures
D Georlette, ZO Jonsson, F Van Petegem, JP Chessa, J Van Beeumen, ...
European journal of biochemistry 267 (12), 3502-3512, 2000
Disease mutations in the ryanodine receptor N-terminal region couple to a mobile intersubunit interface
L Kimlicka, K Lau, CC Tung, F Van Petegem
Nature communications 4 (1), 1-10, 2013
Alanine-scanning mutagenesis defines a conserved energetic hotspot in the CaVα1 AID-CaVβ interaction site that is critical for channel modulation
F Van Petegem, KE Duderstadt, KA Clark, M Wang, DL Minor Jr
Structure 16 (2), 280-294, 2008
Multiple C‐terminal tail Ca2+/CaMs regulate CaV1.2 function but do not mediate channel dimerization
EY Kim, CH Rumpf, F Van Petegem, RJ Arant, F Findeisen, ES Cooley, ...
The EMBO journal 29 (23), 3924-3938, 2010
The structural biology of voltage-gated calcium channel function and regulation
F Van Petegem, DL Minor Jr
Biochemical Society Transactions 34 (5), 887-893, 2006
The clinical and genetic spectrum of catecholaminergic polymorphic ventricular tachycardia: findings from an international multicentre registry
TM Roston, Z Yuchi, PJ Kannankeril, J Hathaway, JM Vinocur, ...
Ep Europace 20 (3), 541-547, 2018
Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological …
AE Trane, D Pavlov, A Sharma, U Saqib, K Lau, F Van Petegem, ...
Journal of biological chemistry 289 (19), 13273-13283, 2014
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