|Cyclooxygenase‐1 haplotype modulates platelet response to aspirin|
AO Maree, RJ Curtin, A Chubb, C Dolan, D Cox, J O'brien, P Crean, ...
Journal of Thrombosis and Haemostasis 3 (10), 2340-2345, 2005
|Open source drug discovery with the malaria box compound collection for neglected diseases and beyond|
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
|Elucidating the role of Staphylococcus epidermidis serine–aspartate repeat protein G in platelet activation|
MP Brennan, A Loughman, M Devocelle, S Arasu, AJ Chubb, TJ Foster, ...
Journal of thrombosis and haemostasis 7 (8), 1364-1372, 2009
|Roles of the juxtamembrane and extracellular domains of angiotensin-converting enzyme in ectodomain shedding|
S PANG, AJ CHUBB, SLU SCHWAGER, MRW EHLERS, ED STURROCK, ...
Biochemical Journal 358 (1), 185-192, 2001
|RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin αIIbβ3|
TM Brophy, M Raab, H Daxecker, KG Culligan, I Lehmann, AJ Chubb, ...
Biochemical and biophysical research communications 369 (4), 1088-1093, 2008
|Modulation of juxtamembrane cleavage (“shedding”) of angiotensin-converting enzyme by stalk glycosylation: evidence for an alternative shedding protease|
SLU Schwager, AJ Chubb, RR Scholle, WF Brandt, R Mentele, ...
Biochemistry 38 (32), 10388-10397, 1999
|A novel platinum complex of the histone deacetylase inhibitor belinostat: rational design, development and in vitro cytotoxicity|
JP Parker, H Nimir, DM Griffith, B Duff, AJ Chubb, MP Brennan, ...
Journal of inorganic biochemistry 124, 70-77, 2013
|Monoclonal antibodies 1B3 and 5C8 as probes for monitoring the integrity of the C-terminal end of soluble angiotensin-converting enzyme|
IV Balyasnikova, ZL Sun, FE Franke, YV Berestetskaya, AJ Chubb, ...
Hybridoma 24 (1), 14-26, 2005
|CycloPs: generating virtual libraries of cyclized and constrained peptides including nonnatural amino acids|
FJ Duffy, M Verniere, M Devocelle, E Bernard, DC Shields, AJ Chubb
Journal of chemical information and modeling 51 (4), 829-836, 2011
|Homologous substitution of ACE C-domain regions with N-domain sequences: effect on processing, shedding, and catalytic properties|
ZL Woodman, SLU Schwager, P Redelinghuys, AJ Chubb, ...
Walter de Gruyter 387 (8), 1043-1051, 2006
|The productive conformation of prostaglandin G2 at the peroxidase site of prostaglandin endoperoxide H synthase: docking, molecular dynamics, and site-directed mutagenesis studies|
AJ Chubb, DJ Fitzgerald, KB Nolan, E Moman
Biochemistry 45 (3), 811-820, 2006
|Phorbol ester-induced juxtamembrane cleavage of angiotensin-converting enzyme is not inhibited by a stalk containing intrachain disulfides|
SLU Schwager, AJ Chubb, RR Scholle, WF Brandt, C Eckerskorn, ...
Biochemistry 37 (44), 15449-15456, 1998
|Identification of Mycobacterium tuberculosis signal sequences that direct the export of a leaderless β-lactamase gene product in Escherichia coli|
AJ Chubb, ZL Woodman, FMPR da Silva Tatley, HJ Hoffmann, ...
Microbiology 144 (6), 1619-1629, 1998
|Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain|
AJ Chubb, SLU Schwager, ZL Woodman, MRW Ehlers, ED Sturrock
Biochemical and biophysical research communications 297 (5), 1225-1230, 2002
|Parallel synthesis and in vitro activity of novel anthranilic hydroxamate-based inhibitors of the prostaglandin H 2 synthase peroxidase activity|
J Lee, AJ Chubb, E Moman, BM McLoughlin, CT Sharkey, JG Kelly, ...
Organic & biomolecular chemistry 3 (20), 3678-3685, 2005
|Cleavage of disulfide-bridged stalk domains during shedding of angiotensin-converting enzyme occurs at multiple juxtamembrane sites|
SLU Schwager, AJ Chubb, ZL Woodman, L Yan, R Mentele, MRW Ehlers, ...
Biochemistry 40 (51), 15624-15630, 2001
|Integrated computational prediction and experimental validation identifies promiscuous T cell epitopes in the proteome of Mycobacterium bovis|
D Farrell, G Jones, C Pirson, K Malone, K Rue-Albrecht, AJ Chubb, ...
Microbial genomics 2 (8), 2016
|Deletion of the cytoplasmic domain increases basal shedding of angiotensin-converting enzyme|
AJ Chubb, SLU Schwager, E van der Merwe, MRW Ehlers, ED Sturrock
Biochemical and biophysical research communications 314 (4), 971-975, 2004
|Proteolytic release of membrane proteins: studies on a membrane-protein-solubilizing activity in CHO cells|
MRW Ehlers, SLU Schwager, AJ Chubb, RR Scholle, WF Brandt, ...
Immunopharmacology 36 (2-3), 271-278, 1997
|Genomes2Drugs: identifies target proteins and lead drugs from proteome data|
D Toomey, HC Hoppe, MP Brennan, KB Nolan, AJ Chubb
PLoS One 4 (7), e6195, 2009