Functional expression of human mitochondrial CYP11B2 in fission yeast and identification of a new internal electron transfer protein, etp1 M Bureik, B Schiffler, Y Hiraoka, F Vogel, R Bernhardt Biochemistry 41 (7), 2311-2321, 2002 | 123 | 2002 |
The human steroid hydroxylases CYP11B1 and CYP11B2 M Bureik, M Lisurek, R Bernhardt Walter de Gruyter 383 (10), 1537-1551, 2002 | 108 | 2002 |
Development of a test system for inhibitors of human aldosterone synthase (CYP11B2): screening in fission yeast and evaluation of selectivity in V79 cells PB Ehmer, M Bureik, R Bernhardt, U Müller, RW Hartmann The Journal of Steroid Biochemistry and Molecular Biology 81 (2), 173-179, 2002 | 105 | 2002 |
Vitamin D3 Metabolism in Human Glioblastoma Multiforme: Functionality of CYP27B1 Splice Variants, Metabolism of Calcidiol, and Effect of Calcitriol B Diesel, J Radermacher, M Bureik, R Bernhardt, M Seifert, J Reichrath, ... Clinical Cancer Research 11 (15), 5370-5380, 2005 | 99 | 2005 |
Efficient conversion of 11-deoxycortisol to cortisol (hydrocortisone) by recombinant fission yeast Schizosaccharomyces pombe CA Drăgan, S Zearo, F Hannemann, R Bernhardt, M Bureik FEMS yeast research 5 (6-7), 621-625, 2005 | 80 | 2005 |
Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase S Ulmschneider, U Müller-Vieira, M Mitrenga, RW Hartmann, ... Journal of medicinal chemistry 48 (6), 1796-1805, 2005 | 76 | 2005 |
Convenient gram-scale metabolite synthesis by engineered fission yeast strains expressing functional human P450 systems CA Drăgan, FT Peters, P Bour, AE Schwaninger, SM Schaan, I Neunzig, ... Applied biochemistry and biotechnology 163, 965-980, 2011 | 71 | 2011 |
A fluorimetric assay for cortisol D Appel, RD Schmid, CA Dragan, M Bureik, VB Urlacher Analytical and bioanalytical chemistry 383, 182-186, 2005 | 68 | 2005 |
Production of human phase 1 and 2 metabolites by whole-cell biotransformation with recombinant microbes A Zöllner, D Buchheit, MR Meyer, HH Maurer, FT Peters, M Bureik Bioanalysis 2 (7), 1277-1290, 2010 | 61 | 2010 |
Challenges of steroid biotransformation with human cytochrome P450 monooxygenase CYP21 using resting cells of recombinant Schizosaccharomyces pombe D Zehentgruber, CA Drǎgan, M Bureik, S Lütz Journal of biotechnology 146 (4), 179-185, 2010 | 61 | 2010 |
Human CYP4Z1 catalyzes the in-chain hydroxylation of lauric acid and myristic acid A Zoellner, CA Dragan, D Pistorius, R Müller, HB Bode, FT Peters, ... Walter de Gruyter 390 (4), 313-317, 2009 | 61 | 2009 |
Development of test systems for the discovery of selective human aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1) inhibitors.: Discovery of a new lead compound for … M Bureik, K Hübel, CA Dragan, J Scher, H Becker, N Lenz, R Bernhardt Molecular and cellular endocrinology 217 (1-2), 249-254, 2004 | 61 | 2004 |
The adrenodoxin-like ferredoxin of Schizosaccharomyces pombe mitochondria B Schiffler, M Bureik, W Reinle, EC Müller, F Hannemann, R Bernhardt Journal of inorganic biochemistry 98 (7), 1229-1237, 2004 | 59 | 2004 |
Coexpression of redox partners increases the hydrocortisone (cortisol) production efficiency in CYP11B1 expressing fission yeast Schizosaccharomyces pombe T Hakki, S Zearo, CA Drăgan, M Bureik, R Bernhardt Journal of biotechnology 133 (3), 351-359, 2008 | 58 | 2008 |
Biotechnological synthesis of drug metabolites using human cytochrome P450 2D6 heterologously expressed in fission yeast exemplified for the designer drug metabolite 4 … FT Peters, CA Dragan, DR Wilde, MR Meyer, J Zapp, M Bureik, ... Biochemical pharmacology 74 (3), 511-520, 2007 | 54 | 2007 |
Steroid hydroxylation: microbial steroid biotransformations using cytochrome P450 enzymes M Bureik, R Bernhardt Modern biooxidation: enzymes, reactions and applications, 155-176, 2007 | 53 | 2007 |
Production of ibuprofen acyl glucosides by human UGT2B7 D Buchheit, CA Drăgan, EI Schmitt, M Bureik Drug metabolism and disposition 39 (12), 2174-2181, 2011 | 49 | 2011 |
CYP21-catalyzed production of the long-term urinary metandienone metabolite 17β-hydroxymethyl-17α-methyl-18-norandrosta-1, 4, 13-trien-3-one: a contribution to the fight … A Zöllner, MK Parr, CA Drăgan, S Dräs, N Schlörer, FT Peters, HH Maurer, ... Walter de Gruyter 391 (1), 119-127, 2010 | 48 | 2010 |
Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized recombinant fission yeast Q Yan, D Machalz, A Zoellner, EJ Sorensen, G Wolber, M Bureik Biochemical pharmacology 146, 174-187, 2017 | 47 | 2017 |
Glucuronide production by whole-cell biotransformation using genetically engineered fission yeast Schizosaccharomyces pombe CA Drăgan, D Buchheit, D Bischoff, T Ebner, M Bureik Drug metabolism and disposition 38 (3), 509-515, 2010 | 47 | 2010 |