Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1680* | 2020 |
Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone S Behjati, PS Tarpey, N Presneau, S Scheipl, N Pillay, P Van Loo, ... Nature genetics 45 (12), 1479-1482, 2013 | 785 | 2013 |
Recurrent PTPRB and PLCG1 mutations in angiosarcoma S Behjati, PS Tarpey, H Sheldon, I Martincorena, P Van Loo, G Gundem, ... Nature genetics 46 (4), 376-379, 2014 | 298 | 2014 |
Mutational signatures of ionizing radiation in second malignancies S Behjati, G Gundem, DC Wedge, ND Roberts, PS Tarpey, SL Cooke, ... Nature communications 7 (1), 1-8, 2016 | 262 | 2016 |
First-in-human dose study of the novel transforming growth factor-β receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma J Rodon, MA Carducci, JM Sepulveda-Sánchez, A Azaro, E Calvo, ... Clinical Cancer Research 21 (3), 553-560, 2015 | 248 | 2015 |
Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV-tumors M Lechner, GM Frampton, T Fenton, A Feber, G Palmer, A Jay, N Pillay, ... Genome medicine 5, 1-12, 2013 | 242 | 2013 |
Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma PS Tarpey, S Behjati, SL Cooke, P Van Loo, DC Wedge, N Pillay, ... Nature genetics 45 (8), 923-926, 2013 | 216 | 2013 |
Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional‐based study N Presneau, A Shalaby, H Ye, N Pillay, D Halai, B Idowu, R Tirabosco, ... The Journal of pathology 223 (3), 327-335, 2011 | 215 | 2011 |
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma S Behjati, PS Tarpey, K Haase, H Ye, MD Young, LB Alexandrov, ... Nature communications 8 (1), 15936, 2017 | 214 | 2017 |
Signatures of copy number alterations in human cancer CD Steele, A Abbasi, SMA Islam, AL Bowes, A Khandekar, K Haase, ... Nature 606 (7916), 984-991, 2022 | 195 | 2022 |
Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast‐rich mimics N Presneau, D Baumhoer, S Behjati, N Pillay, P Tarpey, PJ Campbell, ... The Journal of Pathology: Clinical Research 1 (2), 113-123, 2015 | 158 | 2015 |
Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors ND Anderson, R de Borja, MD Young, F Fuligni, A Rosic, ND Roberts, ... Science 361 (6405), eaam8419, 2018 | 150 | 2018 |
Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor SMA Islam, M Díaz-Gay, Y Wu, M Barnes, R Vangara, EN Bergstrom, ... Cell genomics 2 (11), 2022 | 149 | 2022 |
The driver landscape of sporadic chordoma PS Tarpey, S Behjati, MD Young, I Martincorena, LB Alexandrov, ... Nature communications 8 (1), 890, 2017 | 130 | 2017 |
A common single-nucleotide variant in T is strongly associated with chordoma N Pillay, V Plagnol, PS Tarpey, SB Lobo, N Presneau, K Szuhai, D Halai, ... Nature genetics 44 (11), 1185-1187, 2012 | 130 | 2012 |
Recurrent rearrangements of FOS and FOSB define osteoblastoma MW Fittall, W Mifsud, N Pillay, H Ye, AC Strobl, A Verfaillie, ... Nature communications 9 (1), 2150, 2018 | 117 | 2018 |
Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced … J Rodón, M Carducci, JM Sepulveda-Sánchez, A Azaro, E Calvo, ... Investigational new drugs 33, 357-370, 2015 | 114 | 2015 |
An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma AC Nelson, N Pillay, S Henderson, N Presneau, R Tirabosco, D Halai, ... The Journal of pathology 228 (3), 274-285, 2012 | 106 | 2012 |
DNA replication vulnerabilities render ovarian cancer cells sensitive to poly (ADP-ribose) glycohydrolase inhibitors N Pillay, A Tighe, L Nelson, S Littler, C Coulson-Gilmer, N Bah, A Golder, ... Cancer Cell 35 (3), 519-533. e8, 2019 | 97 | 2019 |
Undifferentiated sarcomas develop through distinct evolutionary pathways CD Steele, M Tarabichi, D Oukrif, AP Webster, H Ye, M Fittall, P Lombard, ... Cancer Cell 35 (3), 441-456. e8, 2019 | 93 | 2019 |