Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death M Nyegaard, MT Overgaard, MT Søndergaard, M Vranas, ER Behr, ... The American Journal of Human Genetics 91 (4), 703-712, 2012 | 448 | 2012 |
A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice H Østergaard, J Lund, PJ Greisen, S Kjellev, A Henriksen, N Lorenzen, ... Blood, The Journal of the American Society of Hematology 138 (14), 1258-1268, 2021 | 42 | 2021 |
ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity J Lund, OH Olsen, ES Sørensen, HR Stennicke, HH Petersen, ... Journal of Biological Chemistry 288 (29), 21367-21375, 2013 | 33 | 2013 |
Heparin-binding mechanism of the IGF2/IGF-binding protein 2 complex J Lund, MT Søndergaard, CA Conover, MT Overgaard Journal of molecular endocrinology 52 (3), 345-355, 2014 | 25 | 2014 |
Mim8-A next-generation FVIII mimetic bi-specific antibody-potently restores the hemostatic capacity in hemophilia a settings in vitro and in vivo SL Kjellev, H Østergaard, MB Hermit, K Thorn, BG Hansen, R Zhou, ... Blood 134, 96, 2019 | 18 | 2019 |
Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors J Lund, L Troeberg, H Kjeldal, OH Olsen, H Nagase, ES Sørensen, ... Journal of Biological Chemistry 290 (10), 6620-6629, 2015 | 15 | 2015 |
Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma J Lund, AM Elimar Bitsch, M Grønbech Rasch, M Enoksson, L Troeberg, ... MAbs 10 (1), 118-128, 2018 | 6 | 2018 |
In vitro effects of combining Mim8 with factor VIII, FVIIa, and activated prothrombin complex concentrates in thrombin generation assays J Lund, K Jensen, L Burnier, M Ezban Journal of Thrombosis and Haemostasis 21 (6), 1493-1502, 2023 | 4 | 2023 |
Modulation of the activated protein C pathway in severe haemophilia A patients: The effects of thrombomodulin and a factor V‐stabilizing fab DF Brophy, EJ Martin, BM Mohammed, JC Barrett, JG Kuhn, ME Nolte, ... Haemophilia 23 (6), 941-947, 2017 | 4 | 2017 |
Site‐specific functional roles of the factor X activation peptide in the intrinsic tenase‐mediated factor X activation A Carnbring Bonde, S Rosenørn Hansen, E Johansson, J Rose Bjelke, ... FEBS letters 596 (12), 1567-1575, 2022 | 3 | 2022 |
The functional role of the autolysis loop in the regulation of factor X upon hemostatic response AC Bonde, J Lund, JJ Hansen, JR Winther, PF Nielsen, S Zahn, P Tiainen, ... Journal of Thrombosis and Haemostasis 20 (3), 589-599, 2022 | 2 | 2022 |
A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa AB Sorensen, PJ Greisen, JJ Madsen, J Lund, G Andersen, ... Scientific Reports 12 (1), 3747, 2022 | 1 | 2022 |
Factor x binders enhancing fx activation J Lund, K Thorn, MN Harndahl, MA Buyse, E De Tavernier, S Steffensen US Patent 11,787,874, 2023 | | 2023 |
05. Hémostase: endothélium, Willebrand et hémophilie M Ezban, K Jensen, J Lund, J Bovet Hématologie 28 (1), 35-41, 2022 | | 2022 |
Prolonging coagulant activity of factor Xa under hemophilic conditions by site-specific N-glycosylation of the surface-exposed autolysis loop AC Bonde, J Lund, JJ Hansen, JR Winther, S Zahn, P Tiainen, OH Olsen, ... bioRxiv, 2021.07. 01.450767, 2021 | | 2021 |
Liants de facteur x renforçant l'activation fx MA Buyse, MN Harndahl, J Lund, S Steffensen, E De Tavernier, K Thorn | | 2020 |
Mette Nyegaard,* Michael T. Overgaard, 2, 8 Mads T. Søndergaard, 2 Marta Vranas, Elijah R. Behr, 3 LL Hildebrandt, J Lund, PL Hedley, AJ Camm, G Wettrell, I Fosdal, ... The American Journal of Human Genetics 91, 703-712, 2012 | | 2012 |
Development of Real Time Proteolytic Assays using Fluorescent Protein Substrates SH Jensen, J Lund, MT Overgaard | | 2011 |
Heparin binding properties of the IGF-II/IGFBP-2 complex J Lund, MT Søndergaard, SH Jensen, F Aasted, EK Andresen, ... | | 2010 |
OR6, 35 Heparin binding properties of the IGF-II/IGFBP-2 complex J Lund, MT Søndergaard, SH Jensen, F Aasted, EK Andresen, ... Growth Hormone & IGF Research, S15-S16, 2010 | | 2010 |