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Alexander D Douglas
Alexander D Douglas
Jenner Institute, University of Oxford
Verified email at ndm.ox.ac.uk
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Cited by
Cited by
Year
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet 397 (10269), 99-111, 2021
52732021
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
PM Folegatti, KJ Ewer, PK Aley, B Angus, S Becker, ...
The Lancet 396 (10249), 467-478, 2020
27532020
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
MN Ramasamy, AM Minassian, KJ Ewer, AL Flaxman, PM Folegatti, ...
The Lancet 396 (10267), 1979-1993, 2020
16492020
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four …
M Voysey, SAC Clemens, SA Madhi, LY Weckx, PM Folegatti, PK Aley, ...
The Lancet, 2021
13232021
Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 VOC 202012/01 (B. 1.1. 7)
KRW Emary, T Golubchik, PK Aley, CV Ariani, BJ Angus, S Bibi, B Blane, ...
734*2021
T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial
KJ Ewer, JR Barrett, S Belij-Rammerstorfer, H Sharpe, R Makinson, ...
Nature Medicine, 1-9, 2020
5822020
Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
JR Barrett, S Belij-Rammerstorfer, C Dold, KJ Ewer, PM Folegatti, ...
Nature medicine 27 (2), 279-288, 2021
3302021
The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody. Nat Commun 2: 601
AD Douglas, AR Williams, JJ Illingworth, G Kamuyu, S Biswas, ...
doi. org/10.1038/ncomms1615, 2011
300*2011
The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody
AD Douglas, AR Williams, JJ Illingworth, G Kamuyu, S Biswas, ...
Nature communications 2 (1), 1-9, 2011
2992011
Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002)
A Flaxman, NG Marchevsky, D Jenkin, J Aboagye, PK Aley, B Angus, ...
The Lancet 398 (10304), 981-990, 2021
2692021
ChAd63-MVA–vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans
SH Sheehy, CJA Duncan, SC Elias, P Choudhary, S Biswas, FD Halstead, ...
Molecular Therapy 20 (12), 2355-2368, 2012
2462012
A PfRH5-Based Vaccine Is Efficacious against Heterologous Strain Blood-Stage Plasmodium falciparum Infection in Aotus Monkeys
AD Douglas, GC Baldeviano, CM Lucas, LA Lugo-Roman, C Crosnier, ...
Cell Host & Microbe 17 (1), 130-139, 2015
2402015
Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial
J Frater, KJ Ewer, A Ogbe, M Pace, S Adele, E Adland, J Alagaratnam, ...
The Lancet HIV, 2021
2152021
Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies
KE Wright, KA Hjerrild, J Bartlett, AD Douglas, J Jin, RE Brown, ...
Nature 515 (7527), 427-430, 2014
2092014
Neutralization of Plasmodium falciparum Merozoites by Antibodies against PfRH5
AD Douglas, AR Williams, E Knuepfer, JJ Illingworth, JM Furze, ...
The Journal of Immunology 192 (1), 245-258, 2014
1642014
Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults
C Ogwang, D Kimani, NJ Edwards, R Roberts, J Mwacharo, G Bowyer, ...
Science translational medicine 7 (286), 286re5-286re5, 2015
1602015
Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals
SH Hodgson, KJ Ewer, CM Bliss, NJ Edwards, T Rampling, ...
The Journal of infectious diseases 211 (7), 1076-1086, 2014
1562014
Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions
RO Payne, SE Silk, SC Elias, K Miura, A Diouf, F Galaway, H de Graaf, ...
JCI insight 2 (21), 2017
1362017
Enhancing blockade of Plasmodium falciparum erythrocyte invasion: assessing combinations of antibodies against PfRH5 and other merozoite antigens
AR Williams, AD Douglas, K Miura, JJ Illingworth, P Choudhary, ...
PLoS Pathog 8 (11), e1002991, 2012
1342012
Human antibodies that slow erythrocyte invasion potentiate malaria-neutralizing antibodies
DGW Alanine, D Quinkert, R Kumarasingha, S Mehmood, FR Donnellan, ...
Cell 178 (1), 216-228. e21, 2019
1182019
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