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Chou-Zen Giam
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Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction
LJ Zhao, CZ Giam
Proceedings of the National Academy of Sciences 89 (15), 7070-7074, 1992
3981992
Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in …
LJ Zhao, CZ Giam
Proceedings of the National Academy of Sciences 88 (24), 11445-11449, 1991
2351991
An exposed KID-like domain in human T-cell lymphotropic virus type 1 Tax is responsible for the recruitment of coactivators CBP/p300
R Harrod, Y Tang, C Nicot, HS Lu, A Vassilev, Y Nakatani, CZ Giam
Molecular and Cellular Biology 18 (9), 5052-5061, 1998
2201998
Human T-cell lymphotropic/leukemia virus type 1 Tax abrogates p53-induced cell cycle arrest and apoptosis through its CREB/ATF functional domain
JC Mulloy, T Kislyakova, A Cereseto, L Casareto, A LoMonico, J Fullen, ...
Journal of virology 72 (11), 8852-8860, 1998
2071998
Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation
KT Jeang, C Giam, F Majone, M Aboud
Journal of Biological Chemistry 279 (31), 31991-31994, 2004
2002004
Distinct regions in human T-cell lymphotropic virus type I tax mediate interactions with activator protein CREB and basal transcription factors
N Adya, CZ Giam
Journal of Virology 69 (3), 1834-1841, 1995
1591995
HTLV-I tax gene product activates transcription via pre-existing cellular factors and cAMP responsive element
CZ Giam, YL Xu
Journal of Biological Chemistry 264 (26), 15236-15241, 1989
1571989
p300 and p300/cAMP-responsive element-binding protein associated factor interact with human T-cell lymphotropic virus type-1 Tax in a multi-histone acetyltransferase/activator …
R Harrod, YL Kuo, Y Tang, Y Yao, A Vassilev, Y Nakatani, CZ Giam
Journal of Biological Chemistry 275 (16), 11852-11857, 2000
1482000
Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB
N Adya, LJ Zhao, W Huang, I Boros, CZ Giam
Proceedings of the National Academy of Sciences 91 (12), 5642-5646, 1994
1481994
Mycobacterium tuberculosis and its purified protein derivative activate expression of the human immunodeficiency virus.
MM Lederman, DL Georges, DJ Kusner, P Mudido, CZ Giam, Z Toossi
Journal of acquired immune deficiency syndromes 7 (7), 727-733, 1994
1421994
In vitro selection of DNA elements highly responsive to the human T-cell lymphotropic virus type I transcriptional activator, Tax
S Paca-Uccaralertkun, LJ Zhao, N Adya, JV Cross, BR Cullen, IM Boros, ...
Molecular and Cellular Biology 14 (1), 456-462, 1994
1391994
HTLV-I Tax directly binds the Cdc20-associated anaphase-promoting complex and activates it ahead of schedule
B Liu, S Hong, Z Tang, H Yu, CZ Giam
Proceedings of the National Academy of Sciences 102 (1), 63-68, 2005
1352005
Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat
F Tie, N Adya, WC Greene, CZ Giam
Journal of Virology 70 (12), 8368-8374, 1996
1351996
A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor α
DY Jin, H Teramoto, CZ Giam, RF Chun, JS Gutkind, KT Jeang
Journal of Biological Chemistry 272 (41), 25816-25823, 1997
1321997
Human T-lymphotropic virus type I tax activates I-κB kinase by inhibiting I-κB kinase-associated serine/threonine protein phosphatase 2A
DX Fu, YL Kuo, BY Liu, KT Jeang, CZ Giam
Journal of Biological Chemistry 278 (3), 1487-1493, 2003
1262003
NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ
H Zhi, L Yang, YL Kuo, YK Ho, HM Shih, CZ Giam
PLoS pathogens 7 (4), e1002025, 2011
1212011
HTLV-1 infection and adult T-cell leukemia/lymphoma—a tale of two proteins: tax and HBZ
CZ Giam, OJ Semmes
Viruses 8 (6), 161, 2016
1152016
Activation of the anaphase promoting complex by HTLV‐1 tax leads to senescence
YL Kuo, CZ Giam
The EMBO journal 25 (8), 1741-1752, 2006
1092006
Human T-cell leukemia virus type I oncoprotein Tax represses Smad-dependent transforming growth factor β signaling through interaction with CREB-binding protein/p300
N Mori, M Morishita, T Tsukazaki, CZ Giam, A Kumatori, Y Tanaka, ...
Blood, The Journal of the American Society of Hematology 97 (7), 2137-2144, 2001
1082001
HTLV-1 Tax and adult T-cell leukemia
CZ Giam, KT Jeang
Front Biosci 12 (4), 1, 2007
1002007
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