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Holger Stark
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International union of basic and clinical pharmacology. XCVIII. Histamine receptors
P Panula, PL Chazot, M Cowart, R Gutzmer, R Leurs, WLS Liu, H Stark, ...
Pharmacological reviews 67 (3), 601-655, 2015
5902015
High constitutive activity of native H3 receptors regulates histamine neurons in brain
S Morisset, A Rouleau, X Ligneau, F Gbahou, J Tardivel-Lacombe, ...
Nature 408 (6814), 860-864, 2000
5882000
Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function
E Bézard, S Ferry, U Mach, H Stark, L Leriche, T Boraud, C Gross, ...
Nature medicine 9 (6), 762-767, 2003
4492003
Polypharmacology by design: a medicinal chemist’s perspective on multitargeting compounds
E Proschak, H Stark, D Merk
Journal of medicinal chemistry 62 (2), 420-444, 2018
3722018
Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonist
X Ligneau, JS Lin, G Vanni-Mercier, M Jouvet, JL Muir, CR Ganellin, ...
Journal of Pharmacology and Experimental Therapeutics 287 (2), 658-666, 1998
3181998
Identification of dopamine D1–D3 receptor heteromers: indications for a role of synergistic D1–D3 receptor interactions in the striatum
D Marcellino, S Ferré, V Casadó, A Cortés, B Le Foll, C Mazzola, F Drago, ...
Journal of Biological Chemistry 283 (38), 26016-26025, 2008
2802008
Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells
R Gutzmer, C Diestel, S Mommert, B Köther, H Stark, M Wittmann, ...
The Journal of Immunology 174 (9), 5224-5232, 2005
2772005
The histamine H4 receptor is functionally expressed on TH2 cells
R Gutzmer, S Mommert, M Gschwandtner, K Zwingmann, H Stark, ...
Journal of Allergy and Clinical Immunology 123 (3), 619-625, 2009
2522009
BF2. 649 [1-{3-[3-(4-Chlorophenyl) propoxy] propyl} piperidine, hydrochloride], a nonimidazole inverse agonist/antagonist at the human histamine H3 receptor: Preclinical …
X Ligneau, D Perrin, L Landais, JC Camelin, TPG Calmels, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 365-375, 2007
2452007
DOGS: Reaction-Driven de novo Design of Bioactive Compounds
M Hartenfeller, H Zettl, M Walter, M Rupp, F Reisen, E Proschak, ...
PLoS computational biology 8 (2), e1002380, 2012
2422012
Histamine H3 receptor antagonists go to clinics
K Sander, T Kottke, H Stark
Biological and Pharmaceutical Bulletin 31 (12), 2163-2181, 2008
2272008
Effects of intracerebroventricularly infused histamine and selective H1, H2 and H3 agonists on food and water intake and urine flow in Wistar rats
A Lecklin, P Etu-Seppälä, H Stark, L Tuomisto
Brain research 793 (1-2), 279-288, 1998
2021998
Histamine H3 and H4 receptors as novel drug targets
E Tiligada, E Zampeli, K Sander, H Stark
Expert opinion on investigational drugs 18 (10), 1519-1531, 2009
1842009
Protean agonism at histamine H3 receptors in vitro and in vivo
F Gbahou, A Rouleau, S Morisset, R Parmentier, S Crochet, JS Lin, ...
Proceedings of the National Academy of Sciences 100 (19), 11086-11091, 2003
1752003
Histamine H3 receptor as a potential target for cognitive symptoms in neuropsychiatric diseases
B Sadek, A Saad, A Sadeq, F Jalal, H Stark
Behavioural brain research 312, 415-430, 2016
1732016
[125I] iodoproxyfan, a new antagonist to label and visualize cerebral histamine H3 receptors.
X Ligneau, M Garbarg, ML Vizuete, J Diaz, K Purand, H Stark, ...
Journal of Pharmacology and Experimental Therapeutics 271 (1), 452-459, 1994
1721994
Distinct pharmacology of rat and human histamine H3 receptors: role of two amino acids in the third transmembrane domain
X Ligneau, S Morisset, J Tardivel‐Lacombe, F Gbahou, CR Ganellin, ...
British journal of pharmacology 131 (7), 1247-1250, 2000
1702000
Histamine H4 receptor antagonism reduces hapten‐induced scratching behaviour but not inflammation
K Roßbach, S Wendorff, K Sander, H Stark, R Gutzmer, T Werfel, ...
Experimental dermatology 18 (1), 57-63, 2009
1612009
Pharmacological analysis demonstrates dramatic alteration of D1 dopamine receptor neuronal distribution in the rat analog of L-DOPA-induced dyskinesia
A Berthet, G Porras, E Doudnikoff, H Stark, M Cador, E Bezard, B Bloch
Journal of Neuroscience 29 (15), 4829-4835, 2009
1592009
Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors
C Guigoni, I Aubert, Q Li, VV Gurevich, JL Benovic, S Ferry, U Mach, ...
Parkinsonism & related disorders 11, S25-S29, 2005
1582005
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